Ageing affects heart health by causing mitochondrial dysfunction
Live Forever Club - 28-Oct-2024Chronic inflammation and fibrosis further damage the heart health
Mitochondria News Archive
Nanotechnology revives cellular energy: A breakthrough in mitochondrial regeneration
Nanowerk - 20-Sep-2024New research from Texas A&M develops nanoflowers to restore cellular energy
Orsobio secures $67m to revolutionize metabolic disease treatment
Longevity Technology - 09-Sep-2024Boosting fat loss and preserving muscle with cutting-edge mitochondrial therapy
Vandria secures $30.7m to advance groundbreaking mitochondrial therapy for neurodegenerative diseases
Hevolution Foundation - 21-Aug-2024New funding propels innovative mitophagy-inducing lead compound into clinical trials targeting Alzheimer’s and Parkinson’s
Lucy Therapeutics raises $12.5M to develop mitochondrial therapies
Longevity Technology - 31-May-2024Company is developing therapies for Alzheimer's, Parkinson's, and Rett syndrome
Timeline's Mitopure demonstrates potential to reverse immune system ageing
Business Wire - 06-May-2024Research underscores potential to revolutionise approach to healthy ageing
Silicon Valley startup aims to extend human lifespan with mitochondrial transplants
Live Forever Club - 12-Apr-2024Research aims to extend lifespan and unlock new levels of human health
Cell malfunctions can cause information leakage and trigger inflammation
University of Virginia School of Medicine - 05-Mar-2024The discovery may improve inflammation treatment and anti-ageing interventions
Red light exposure may lower blood sugar levels after meals
Independent - 21-Feb-2024It reduced blood sugar spikes and overall levels in healthy individuals
Daily choices like exercise, diet, and even how you breathe affect your mitochondria
Live Forever Club - 09-Feb-2024Making small changes to your lifestyle can have a significant impact on health
A cellular protein called HKDC1 tidies up mitochondria and lysosomes
Interesting Engineering - 01-Jan-2024This discovery paves the way for potential anti-ageing therapies
MitoRx's $5M funding sets the stage for treating muscle and lung diseases
Longevity Technology - 14-Dec-2023Company's drug targets the root cause of diseases like Duchenne and COPD
$20.6 million fuels Vandria's mission to conquer ageing and chronic diseases
Longevity Technology - 14-Dec-2023Mitophagy-boosting drug candidate VNA-318 preps for clinical trials
ARCUS gene editing technology effectively eliminates mutant mitochondrial DNA
Biospace - 04-Dec-2023Potential therapeutic approach for mitochondrial and other genetic diseases
New peptide-based technology selectively erases ageing cells
Ulsan National Institute of Science and Technology (UNIST) - 14-Sep-2023Mitochondria targeting could lead to new treatments for age-related diseases
New blood test may help in early detection of Parkinson’s disease
Independent - 30-Aug-2023The test could identify drugs that reverse or slow down DNA damage and disease
Mitochondria-targeted compound prevents and treats metabolic syndrome in mice
Buck Institute - 07-Jul-2023Selectively inhibits problematic free radicals - potential breakthrough in treatment of chronic diseases & ageing
Summary of Chris Rinsch presentation at Longevity Med Summit
Live Forever Club - 16-May-2023Explained the production and mechanisms of Urolithin A, and trial results of Timeline's Mitopure
cellvie closes $5.5 million of financing to develop its allogeneic mitochondria therapies
KIZOO Technology Ventures - 06-Feb-2023Mitochondria dysfunction is linked to several ageing-related diseases, including neurodegeneration, so a big potential market
Mutated mtDNA acts as a molecular target for therapeutic treatments of age related diseases
University of Cologne - 16-Dec-2022Targeting and eliminating mutated mtDNA by subjecting it to autophagy with rapamycin been successful
Mitochondria boosting therapy rejuvenates immune system of mice
Longevity Technology - 11-Oct-2022If successful in humans it would improve the outcome of many age-related diseases
Longevity Technology interviews cellvie CEO, Alex Schueller, about therapeutic mitochondria
Longevity Technology - 14-Sep-2022Initially targeting ischemia-reperfusion injury, TMT has potential to treat multiple age-related diseases
$72m funding launching Pretzel Therapeutics pioneering mitochondrial therapies
Biospace - 12-Sep-2022Pretzel targets genome correction, genome expression modulation and mitochondrial quality control
Restructured mitochondrial metabolism linked to survival of human eggs
STAT - 20-Jul-2022Complex I production temporarily halted in quiescent oocytes, promoting fertility
MitoRx Therapeutics' CEO shares insights on fundraising and pitching to investors
UK Innovation & Science Seed Fund - 20-Jul-2022Effectively communicating to investors will translate an ideology into a social benefit
Mitochondrial transplants show efficacy in achieving longevity in humans
Lifespan.io (LEAF) - 19-Jul-2022Mitochondrial transplant raise energetics of the body, so it can withstand longevity treatments
Urolithin A can increase mitochondrial health in living joint tissue and improved mobility
Business Wire - 07-Jul-2022Mitopure can improve mitochondrial health and counteract age-related muscle function decline
Buck researchers discover mitochondrial protein that can increase lifespan
Buck Institute - 18-May-2022In yeast, increasing Tom70 delays ageing related mitochondrial dysfunction
Amazentis’ proprietary Urolithin A-clinically proven to improve muscle function
EurekAlert! - 17-May-2022Mitopure will be offered inside Nestlé Health Science products
New longevity startup MitoRx Therapeutics is developing mitochondria protective drugs
Longevity Technology - 25-Apr-2022Targeting age-related diseases, the company's pre-clinical compounds to progress to the clinic
Senior UCLA scientists public states aim to fight aging to impact numerous diseases
University of California, Los Angeles (UCLA) - 24-Mar-2022Great to see the concept of reversing aging becoming a mainstream ambition - it hasn't always been that way!
New study unveils the role of tau in neurodegenerative disease
Buck Institute - 20-Jan-2022Interactions with mitochondrial & synaptic proteins highlight targets against Tau-mediated disease
Improving mitochondrial function enhances colour vision in old age
New Atlas - 24-Nov-2021Long wavelength exposure partially restores ATP and improves eye function
Three minute exposure to deep red light can improve your eyesight
University College London (UCL) - 24-Nov-2021Morning exposure to long wave deep red light showed 17%-20% improvement in colour vision
Mitlets improve immunity and treat many age-related diseases
Longevity Technology - 22-Oct-2021Experimental therapy to transfuse healthy mitochondria from multiple donors
A new nanoreactor repaired the damaged region in cells by supplying ATP
Singularity Hub - 21-Sep-2021Energy generation in living cells by programmed exosome fusion
Complicated connection between protein shape and mitochondrial health, causing aging
Buck Institute - 07-Sep-2021The “bad” process of pore opening and the “good” process of UPRmt - connection revealed
Penetrable sunscreen agents could reverse skin damage and ageing
SciTechDaily - 12-Aug-2021Two novel compounds fuel mitochondria to maintain energy balance and lower UV damage in the skin
Liver-fat content and bodyweight reduction with effective use of CB4211
GlobeNewswire - 10-Aug-2021Mitochondrial genome used to potentially treat fatty liver and prevent obesity
Elamipretide: a drug to protect your eyes from AMD
Ophthalmology Times - 07-Jul-2021Elamipritide protects your retinal cells from undergoing degeneration
Injecting new mitochondria to replace old, damaged mitochondrial DNA in humans
Lifespan.io (LEAF) - 02-Jun-2021Potential treatment for mitochondrial diseases & dysfunction, and extends lifespan
Recharge your mitochondrial batteries to live longer
Longevity Technology - 27-May-2021Breakthrough in longevity research - cellular energetics may stop or even reverse the ageing process
NR supplementation restored youthfulness to blood in older mice
Lifespan.io (LEAF) - 18-May-2021Lowers age-related defects of blood stem cells & make stem cell transplants more effective
Folds in mitochondria membrane are lost as we age - reducing production of ATP
I Spy Physiology - 12-May-2021Antioxidant treatment reversed mitochondrial ageing via cardiolipin in mice
A natural compound reverses skin wrinkles and hair loss in mice
Longevity Technology - 08-Apr-2021Targets mitochondrial dysfunction - cosmeceuticals on its way to reverse ageing signs in humans
You can have too much of a good thing - including exercise
The Scientist - 23-Mar-20212.5 hours of HIIT in a week reduces mitochondrial respiration, meaning less energy for the body
Highest exercise load lead to reduction in intrinsic mitochondrial function
The Scientist - 23-Mar-2021Substantial mitochondrial respiratory impairment is included with excessive exercise
CohBar's lead candidate may initiate clinical trials in 2022
Longevity Technology - 16-Mar-2021Mitochondrial-based therapy enters IND to tackle IPF and other fibrotic diseases
NAD+ reduces age-related amyloidosis and mitochondrial dysfunction
Lifespan.io (LEAF) - 05-Feb-2021Boosting NAD+ levels improves health span and can treat age-related diseases
Mitrix gains funding to transfuse young mitochondria
Longevity Technology - 28-Jan-2021Trials on mitochondrial transfusion might help tackle many ageing diseases
Inhibition of mitochondrial DNA might suppress tumour growth
Nature - 04-Jan-2021IMTs degraded 1 in 3 cancer cell lines in vitro, and early promise in mice
Antihypertesive drug found a new purpose in ageing
EurekAlert! - 18-Dec-2020Big gains in c. elegans life expectancy rarely translates to humans, but another avenue to research
Red light therapy could be the clue to restore your eyesight
China Global Television Network (CGTN) - 13-Dec-2020Red light improved health and lifespan of fruit flies; might work on humans too
Decoded - why travelling through space can make you older
iNews - 25-Nov-2020Mitochondrial damage accelerates ageing on exposure to space radiation and microgravity
Regulatory role of GDF 15 related to ageing and metabolism in humans and mice
Longevity Technology - 06-Aug-2020Discovery of this homeostatic function just may be the first step but it looks promising
Scientists go where no gene-editing tool has gone before
Lifespan.io (LEAF) - 14-Jul-2020DddA able to target mitochondrial DNA (mtDNA) by splitting in half and hitching a ride
A gene editing tool to treat mitochondrial mutations
The Scientist - 09-Jul-2020Derived from bacterial toxin - can make single base pair changes
Humanin is a regulator peptide of healthspan and lifespan
Science Daily - 24-Jun-2020Longer life results in less offspring - sounds like the ideal compromise to me!
Increasing ovarian NAD+ improved mitochondrial function in mice egg cells
Lifespan.io (LEAF) - 11-Jun-2020Supplementation also shown to reverse ovarian ageing
Drug that can safely reverse obesity and insulin resistance developed
Medical Xpress - 08-Jun-2020Proven in mice study to be non-toxic, nor affects brain hunger cues
Experts develop new novel detection method for mitophagy
Lifespan.io (LEAF) - 28-May-2020A discovery proven to be of help in therapeutic studies of neurodegeneration
Vitamin B3 is a good option to correct the NAD+ deficit in humans
Phys.org - 14-May-2020NAD+ deficiency is for real and it happens in humans too
Possible culprits in genetic diseases, cancer, and ageing found
National Institute on Aging - 14-May-2020Research shows it could be caused by mitochondrial DNA mutations
Mitochondrial transplants are successful but benefits are short lived
Lifespan.io (LEAF) - 25-Mar-2020May be a solution to ageing related mitochondrial dysfunction which leads to diseases
Metastudy reviews impact of mitochondrial aging on cardiovascular disease
Lifespan.io (LEAF) - 18-Mar-2020Still lots to discover, but SENS already looking at ways to stop it in its tracks
Cognitive and motor function improve with mitotherapy in aged mice
Fight Aging! - 06-Mar-2020These are among other benefits revealing new insights into anti-aging research
How mitochondria drives senescence, affecting healthy ageing
EurekAlert! - 20-Feb-2020Potential target for drug-based interventions to delay cellular ageing identified
NMN restores neurovascular health, improves cerebral blood flow in ageing
Lifespan.io (LEAF) - 17-Feb-2020Mitochondria-targeted interventions in old mice could be key to age-related diseases.
Repletion of NAD+ has some degree of improvement on ageing in mice
Fight Aging! - 07-Feb-2020Needs to study more on NAD+ interventions in order to achieve significant benefits
Hyperbaric oxygen therapy's impact on cardiac function
Jerusalem Post - 04-Feb-2020Protocols were evaluated on the patients with “normal” aging heart
New discovery showed mitochondria found living in the blood
Lifespan.io (LEAF) - 27-Jan-2020Mitochondria living in the blood definitely has some functions, further research needed to discover
How SENS is tackling mitochondrial DNA damage
Lifespan.io (LEAF) - 17-Jan-2020Amutha Boominathan presented her work on MitoSENS project at Ending Age-Related Diseases 2019
An enzyme that prolongs lifespan in roundworms discovered
INVERSE - 07-Jan-2020Results have been replicated in cultured human cells - a new hope for life extension?
Metabolism and mitochondria gene function impacted by spaceflight
New Scientist - 07-Nov-2019Most changes reversed when back on Earth - but what about Mars microgravity?
Experimental drug reversed the fat build up in the liver
New Scientist - 02-Oct-2019Tests done on animals suggest that CRMP reduces heart disease risk and animals didn't lose weight
From cryonic baths to ozone saunas, to the search of magic pill
Wired - 10-Sep-2019In 2018 consumers spent $43 billion on anti-ageing products according to Orbis analysis
It's time for considering drug-exercise interactions
New York Times - 19-Jun-2019Interesting - metformin plus exercise did not have an additive effect
Metabolite found in pomegranates has anti-ageing effects
Medical Xpress - 17-Jun-2019Urolithin A could help slow certain aging processes, improve the functioning of mitochondria
Environmental pollutants in household items can affect ageing
INVERSE - 02-May-2019Reduces length of telomeres and alters mitochondrial DNA levels in cells
Cellular aging halted by hydrogen sulfide gas
Medical News Today - 07-Aug-20183 compounds designed to deliver minute amounts of hydrogen to mitochondria inhibit cellular aging
Doctors Repair Infants’ Damaged Hearts With Mitochondria
Futurism - 10-Jul-2018Procedure transplants mitochondria into infant’s muscle cells to prevent heart disease
Human Trial of Mitochondrially Targeted Antioxidant MitoQ
Fight Aging! - 20-Apr-2018Aortic stiffness was lower in participants with elevated baseline levels.
Inhibition of ageing maybe the solution for Alzheimer's
The San Diego Union-Tribune - 19-Jan-2018Will be successful than drugs targeting specific aspects of Alzheimer's
Mitochondrial Contribution to Aging and Age-Related Disease
Fight Aging! - 21-Dec-2017Mitochondria are primarily responsible for generating chemical energy stores.
Boosting Mitochondrial Quality Control to Combat Alzheimer's
Lifespan.io (LEAF) - 08-Dec-2017Diseases like Alzheimer’s are the result of the loss of proteostasis.
Key to Diseases in Mitochondrial DNA Mutations
Longevity Facts - 06-Dec-2017DNA sequences between mitochondria inside a single cell are vastly different.
SRF has made progress in the fight against ageing
Lifespan.io (LEAF) - 05-Dec-2017R&D phase in SENS repair approach has shown promising results
High-intensity interval training (HIIT) Can Slow Aging
Care2 - 11-Sep-2017Recent research has shown that high-intensity interval training (HIIT) may actually reduce and reverse longterm damage done to mitochondria—the powerhouse of the cell.
Biologists slow ageing process in fruit flies
IB Times - 07-Sep-2017As people age, their mitochondria often become damaged - damaging the cells where any build-up occurs.
British billionaire gambles on an anti-aging upstart
Endpoints News - 26-Jul-2017We are at an inflection point for the treatment of aging.
Removing mutated DNA from mitochondria to turn back the aging clock
Caltech - 18-Nov-2016Hundreds to thousands of mitochondria per cell each carrying its own mtDNA.
Heavy Isotopes and Slowed Aging
Fight Aging! - 01-Sep-2016Raising short-lived species on a low dosage of heavy water appears to modestly slow aging.
Nicotinamide riboside (NR) stops the aging process in organs
Kurzweil Network - 06-May-2016EPFL researchers restore ability of mice organs to regenerate – also extending life.
Mitochondria trigger cell aging
Medical Xpress - 04-Feb-2016Probably only 1 of many aging factors at cellular level – but every little helps as reducing aging a little buys a few more years for science to reduce it even more.
/calorie-restriction-cr-thumbnail.jpg "Click to read article")
Review of Mechanisms that Slow Aging from Calorie Restriction
Fight Aging! - 06-Jan-2015CR changes near everything in the operation of metabolism and slows near every measure of aging making it difficult to figure out chains of cause and effect.
