Precision genetics: unlocking the secrets of mutation
Harvard University - 13-Nov-2024A revolutionary tool targets specific genes, advancing our understanding of evolution and disease
Gene Therapy News Archive
Dyno partners with Roche to enhance gene therapy for brain diseases
Longevity Technology - 25-Oct-2024They aim to use AI-driven capsid design for delivery for complex treatments
Nanoparticles deliver tools to fix gene mistakes in lung cells
The Scientist - 15-Oct-2024Tests in mice and human cells show long-lasting gene correction
Nanopillars unlock the nucleus without harming cells
Science Daily - 02-Oct-2024A new breakthrough in nanotechnology offers a non-invasive way to access the cell's genetic material
Rejuvenate Bio secures $4M to advance gene therapy for a devastating heart disease
BioProcess International - 27-Aug-2024A promising one-time treatment approach for arrhythmogenic cardiomyopathy
Gene-editing offers NHS patients potential cure for beta thalassemia
BBC - 08-Aug-2024This revolutionary treatment could eliminate the need for lifelong blood transfusions
Beacon Therapeutics secures $170M to develop gene therapies for retinal diseases
Longevity Technology - 05-Jul-2024Company is particularly focusing on less invasive treatments for dry AMD and XLRP
NHS offers novel gene therapy for haemophilia B, potentially curing patients
BBC - 27-Jun-2024The therapy is initially available at eight centers across the UK
New gene-editing tool, 'bridge editing,' surpasses CRISPR in precise DNA alterations
New Scientist - 26-Jun-2024Potential for advancements in medicine, agriculture, and other fields
Scientists discover key protein that could prevent age-related vision loss
Independent - 05-Jun-2024Boosting IRAK-M protein protects retina in the eyes and paves way for potential AMD treatment
ExpressionEdits secures $13M for developing AI-powered gene therapy
Longevity Technology - 03-Jun-2024Company aims to improve protein production in genetic medicine
Toddler born with hearing loss can now hear thanks to new gene therapy trial
The Guardian - 09-May-2024Therapy offers hope for a potential cure for certain types of hearing loss
Gene therapy triggers natural blood vessel growth in angina patients
EurekAlert! - 02-May-2024Treatment shows improved blood flow, exercise tolerance and reduced symptoms
Gordian Biotechnology raises $60M to accelerate gene therapy discovery
Longevity Technology - 26-Apr-2024AI-powered platform predicts drugs for age-related diseases with 80% accuracy
AI designs a more precise CRISPR gene editor for use in human cells
Singularity Hub - 25-Apr-2024This could lead to safer and more effective treatments for genetic diseases
Scientists overcome hurdles to design human artificial chromosomes
Singularity Hub - 26-Mar-2024New technique delivers more genetic material, paving way for safer & effective gene therapies
Nanoscope's gene therapy offers hope for patients blinded by inherited retinal disease
FierceBiotech - 26-Mar-2024Phase 2 trial results show significant vision improvement, plans for FDA approval
Columbia scientists use CRISPR gene editing to boost energy production in eye cells
Medical Xpress - 21-Mar-2024This experimental therapy targets a common metabolic issue in Retinitis Pigmentosa
Gene therapy for rare brain disease sets a new pricing record at $4.25 million
FiercePharma - 20-Mar-2024Its record-breaking price raises questions about affordability and access
Novel approach effectively silences cholesterol genes in mice for a year
News Medical - 01-Mar-2024This could lead to long-lasting cholesterol treatments without genetic damages
Invisible stem cells treat disease without triggering immune response
Nature - 28-Feb-2024Genetically-modified stem cells avoid immune rejection, paving way for universal therapies for everyone
Diabetic monkeys regain insulin independence after transplant of unique insulin cells
Live Forever Club - 23-Feb-2024This could lead to a safer and better treatment for type 1 diabetes.
RNA editing therapies for genetic diseases signify medical research progress
Nature - 16-Feb-2024Unlike editing DNA itself, this new approach makes temporary changes to RNA
Rejuvenate Bio partners with animal company to develop gene therapy for canine osteoarthritis
Biospace - 14-Feb-2024Single dose injection targets root causes, offering long-term relief & improved quality of life
Fractyl raised $110 million to develop treatments for obesity and diabetes
Longevity Technology - 05-Feb-2024They picked RJVA-001, a gene therapy, as their first clinical candidate
Dresden merges recombinases & DNA-binding domains for tailored gene editing
Medical Xpress - 31-Jan-2024The research offers safer and more precise ways to treat genetic disorders
A CRISPR gene editing technique has cured hereditary angioedema in a single-dose
New Scientist - 31-Jan-2024It demonstrated a remarkable cure rate, rather than merely offering a treatment
Regenxbio-AbbVie gene therapy reduces eye injections for AMD patients
FierceBiotech - 17-Jan-2024Patients’ vision and retinal health remained stable after six months
MeiraGTx at the forefront of gene therapy for cancer, obesity, and vision loss
Evening Standard - 21-Dec-2023London biotech promises revolutionary therapies by replacing faulty genes & flipping gene switches
Revolutionizing gene editing: Tome Biosciences unveils groundbreaking DNA integration technology
Genetic Engineering & Biotechnology News (GEN) - 19-Dec-2023Tome Biosciences secures $213m to advance next-gen gene editing
ARCUS gene editing technology effectively eliminates mutant mitochondrial DNA
Biospace - 04-Dec-2023Potential therapeutic approach for mitochondrial and other genetic diseases
UK's approval of casgevy paves the way for gene-edited treatment of blood disorders
BBC - 16-Nov-2023Casgevy offers hope for patients with sickle cell disease and beta thalassemia
Single-dose gene-editing therapy offers permanent solution to high cholesterol levels
New Scientist - 14-Nov-2023Early results show promise in eliminating the need for lifelong statins
A new gene therapy treatment has helped deaf children hear for the first time
MIT Technology Review - 27-Oct-2023Treatment delivers a working copy of a missing gene to the inner ear
Beyond CRISPR: Fanzors, a new era of programmable DNA editing tools
Massachusetts Institute of Technology (MIT) - 13-Oct-2023Scientists discover a vast array of RNA-guided enzymes in diverse organisms
Broken string secures $15m to make cell and gene therapy safer, more accessible
Longevity Technology - 19-Sep-2023Company's INDUCE-seq platform could revolutionise cell & gene therapy efficiency
Amber Bio secures $26M funding to advance new gene editing technologies
Longevity Technology - 07-Aug-2023By editing RNA instead of DNA, the company aims to treat multiple undruggable genetic diseases safely
Voyager's new gene therapy targets amyloid plaques in Alzheimer's disease
FierceBiotech - 04-Aug-2023New treatment approach could be more effective in lowering the risk of serious side effects
Novel method facilitates single-cell expansion of gene edited stem cells
Lifespan.io (LEAF) - 17-Jul-2023Its polymer-supplemented culture system enables cell expansion without harmful mutations
Gene therapy restores partial red colour vision in total colour blindness patients
New Scientist - 10-Jul-2023Despite the limited improvement, gene therapy offers hope for future breakthroughs in restoring vision
Game-changing bacteriophage could revolutionize gene therapy
New Scientist - 30-May-2023Ability to carry vast amounts of DNA and other molecules promises substantial advancements in gene and cell therapies
Therapeutic applications of base editing clears girl's leukemia
BBC - 11-Dec-2022Base editing can soon be a part in taking control of our genomes to fight genetic diseases
CRISPR based PASTE (Programmable Addition via Site-specific Targeting Elements) tool designed
MIT Media Lab - 24-Nov-2022The new PASTE tool replaces faulty genes in a safer and more efficient way
Jeune Aesthetics moves to the Phase 2 trial for fine lines and wrinkles
Biospace - 17-Nov-2022Targeted gene-delivery hold potential in replenishing the skins key protein, to treat fine lines
Breakthrough gene therapy offers cure for a rare bleeding disorder heamophilia
BBC - 21-Jul-2022Trial results were positive but cautioned the use until proven safe and effective
HTR in Drosophila somatic cells using nikase and CRISPR genetic editing tools
Genetic Engineering & Biotechnology News (GEN) - 05-Jul-2022CRISPR genetic editing tools may be helpful in genetic repair
Lifespan of middle-aged mice increased by a third with telomerase gene therapy
CISION PR Newswire - 19-May-2022Treatment used proprietary CMV vector which is able to deliver multiple genes into the nucleus
Viral-vector gene therapies could unlock healthy life extension in humans
Lifespan.io (LEAF) - 12-May-2022Lifespan of mice greatly extended even when treatment only started at the equivalent of 56 years old
Verve Therapeutics' gene editing therapy may cure heart attacks once and for all
Bloomberg - 06-May-2022Trials underway to test the safety, but affordability and acceptance of gene therapy are major concerns
Gene therapy gel heals wounds in people with rare genetic skin condition
New Scientist - 28-Mar-2022Positive results in clinical trials provide hope for conditions that currently have no specific treatments
Long-term partial reprogramming reversed ageing process in mice
The Guardian - 07-Mar-2022Yamanaka factors restored youthfullness in aged cells, raised hope for new anti-ageing therapies
NHS offers the world's most expensive drug for children with a rare disease
BBC - 04-Feb-2022Libmeldy is life-saving gene therapy now available for use in England
Gene-editing technology, CRISPR, selectively kills drug-resistant superbugs
Deutsche Welle (DW) - 10-Nov-2021A single dose of CRISPR Cas system cleared 99.9% of harmful bacterial in mice
Turning off abnormal genes may cure crippling genetic disease
BBC - 21-Oct-2021Potential gene silencing approach in porphyria and possibly for many other diseases in the future
FDA puts clinical hold on Allogenic CAR T therapy due to safety concerns
FierceBiotech - 08-Oct-2021Chromosome abnormality reported in a clinical trial raises doubts on patient safety
OMEGA, a new powerful gene-editing system similar to CRISPR or so much better
New Atlas - 16-Sep-2021Potential RNA-guiding enzymes that are capable of editing and modifying DNA in human cells
Centaura's human artificial chromosome to treat complex diseases, including ageing
Medium - 10-Sep-2021A breakthrough technology focusing on effective gene therapies for healthy longevity
Lifespan.io interviews George Church about gene therapy and longevity
Lifespan.io (LEAF) - 28-Jul-2021Discusses animal trials, potential human trials, reeducating the FDA and improvements in technology
New CRISPR gene-editing drug for a rare protein-misfolding disorder
pharmaphorum - 28-Jun-2021Phase 1 trial reports, single dose of the drug cuts protein levels by 87% in ATTR amyloidosis
Brain can learn to see again using algae proteins
BBC - 24-May-2021Optogenetics bring back vision partially with light sensing proteins - new hope for the blind
New gene therapy technique, CopyCatcher, more accurate in fruit flies
SciTechDaily - 11-May-2021Targets precise location of mutated gene rather than tagging on anywhere
Gene therapy preserved memory and learning in mice with Alzheimer's
Lifespan.io (LEAF) - 11-May-2021Boosting a vital protein, Caveolin-1, this new technique offers hope against neurodegenerative diseases
Inherited blindness can now be cured with gene therapy
BBC - 29-Apr-2021A breakthrough gene therapy restores eyesight in patients with rare eye disease
Latest CRISPR editing method can turn on/off gene expression
Phys.org - 09-Apr-2021Allows to silence bad genes without modifying the DNA sequence and it is fully reversible
Gene therapy for Alzheimer's disease enters human clinical trial
Forbes - 12-Mar-2021Virus carries gene encoding protein into the brain -possible breakthrough treatment for neurodegenerative diseases
Single gene therapy injection halts spinal muscular atrophy
BBC - 08-Mar-2021Becomes most expensive drug ever approved for the NHS - but no lifetime costs
CRISPR cuts cholesterol by 57% with just one shot
Phys.org - 01-Mar-2021Tiny lipid particles with gene editing machinery selectively targets liver and reduces cholesterol in mice
A look at the government consultation on genetic technologies in agriculture
Nuffield Council on Bioethics - 04-Feb-2021Two kinds of question that people ask about developments in life sciences and biotechnology:
Deactivating ageing gene KAT7 to slow down ageing
Reuters - 20-Jan-2021A potential therapeutic target for ageing, but still a long way to human trials
A gene editing tool used to treat progeria in mice
Science Magazine - 06-Jan-2021Hope to launch a clinical trial in kids soon using this approach
Gene therapy prevented deafness in mice with genetic defects
ISRAEL21c - 04-Jan-2021Scientists to use this approach & treat deafness due to other mutations also
CRISPR's gene editing therapy finds cure for blood cancer
STAT - 05-Dec-2020Early data from Vertex & CRISPR showed promising results to cure blood disorders
MIT professor Richard Young explains how Omega regulates gene expression
Cell and gene - 01-Dec-2020Using Epigenomic Controllers to alter DNA transcription rather than the genes themselves
A novel gene editing tool to fight aggressive cancers
Medical Xpress - 18-Nov-2020Uses CRISPR technology to target and destroy cancer cells
A potential therapy for blinding retinal diseases
National Institutes of Health (NIH) - 03-Nov-2020Researchers engineer novel protein that restores vision in blind mice via gene therapy
Tiny lipid bubbles could deliver gene editing kit to your tissues
Phys.org - 08-Oct-2020Will make it easier to target treatment to specific locations in the body
Old mice show improved muscle function with gene therapy
Lifespan.io (LEAF) - 27-Aug-2020A single injection could treat motor diseases of the aged but needs more human studies
90 % of herpes simplex virus 1 eliminated in infected cells
Lifespan.io (LEAF) - 19-Aug-2020Successful in mice, new approach may ease immune burden of herpes in humans in the future
$95M raised by Taysha for clinical trials of four new gene therapies
FierceBiotech - 05-Aug-2020Company has gathered support from investors to quickly lead therapies to clinic then market
Scientists go where no gene-editing tool has gone before
Lifespan.io (LEAF) - 14-Jul-2020DddA able to target mitochondrial DNA (mtDNA) by splitting in half and hitching a ride
A gene editing tool to treat mitochondrial mutations
The Scientist - 09-Jul-2020Derived from bacterial toxin - can make single base pair changes
Company introduces 'gene writing', to surpass CRISPR's limitations
Wired - 07-Jul-2020New class of gene editors set to remove hurdles of traditional gene therapy
Gene editing lowered blood level cholesterol and triglycerides in monkeys
New York Times - 27-Jun-2020Could prevent not only the complications but the heart disease per se in the future
CRISPR gene editing to cure beta thalassaemia and sickle cell disease
New Scientist - 12-Jun-2020Didn't change the inherited faulty gene, but gene to switch on fetal haemoglobin production
Phase 1 clinical trial for type 1 diabetes cell therapy comes closer
Medical Xpress - 03-Jun-2020A world-first novel technology to treat the disease is now within reach
Automated manufacturing of custom-engineered cell lines
News Medical - 20-May-2020This technology is very promising and has an enormous potential
Follistatin gene therapy to combat osteoarthritis and obesity
Next Big Future - 16-May-2020This new approach doubled muscle mass in mice, reduced its fat
Mapping gene expression regulation in yeast to understand ageing
Google AI Blog - 29-Apr-2020Made possible by Calico's research expertise and Google AI's machine learning tech
CRISPR-Cas9 variants, key to overcoming major limitation in gene editing system
Lifespan.io (LEAF) - 31-Mar-2020Entire genome now targetable, open to interventions for use in combating diseases
A global commission laid out roadmap for gene-editing trials on human embryo
Wired - 09-Mar-2020Strict ethical guidelines to avoid undesirable outcomes in gene-edited babies
Fixing the genes to cure inherited blindness
Guardian - 04-Mar-2020Crispr gene editing is a great but a dangerous tool
First gene therapy for a rare eye disease, now NHS-approved
BBC - 17-Feb-2020This life-changing new gene therapy will halt sight loss and improve vision
CRISPR gene editing to help immune cells target and kill cancer
New Scientist - 06-Feb-2020First CRISPR cancer trial in the world publish its promising findings
Chinese scientist tried genome editing on embryos
Guardian - 31-Dec-2019Research of He Jiankui was a violation of medical regulations
Scientists identify multiple genes responsible for keeping cancer cells alive
Independent - 20-Dec-2019If combined they can form the largest database of genetic information on cancer
NIH and Gates Foundation to invest $100 million each to develop gene therapies
Time Magazine - 24-Nov-2019New hope for the 37.9 million people worldwide living with HIV/AIDS
CRISPR technology edited plant cells after being sprayed on their leaves
New Scientist - 01-Nov-2019Can get into animal cells, so I wonder if this could be used with humans in future?
Prime editing as a way of "editing" genes
BBC - 21-Oct-2019There are around 75,000 mutations caused by DNA errors and prime editing can correct 89% of them
Direct cell to cell transformation without a stem cell stage
TechCrunch - 14-Oct-2019Analyses a huge amount of data without the help of an artificial intelligence
Drug invented for a girl with Batten disease
BBC - 12-Oct-2019Doctors from Boston sequenced in detail whole genome of Mila and found the disease-causing mutation
New gene therapy to treat AMD will last a lifetime
ScienceDaily - 11-Oct-2019A better option than having injections in to the eye once a month
Cervical cancer successfully cured with gene editing in mice
Medical Xpress - 10-Oct-2019If the right genes to tackle are identified, this could be the cure for all cancers
Nonviral gene therapy: the safer option and full of potential
Phys.org - 24-Sep-2019Could it be used to increase the crop yield to fight against world hunger?
New treatment for inherited retinal dystrophies
BBC - 04-Sep-2019Gene therapy presents injecting the healthy gene directly in the eye to produce working protein
Treatment with immune system caused remission in incurable leukaemia
Independent - 02-Sep-2019CAR-T therapy gives hope for the children for whom the standard therapies don't work
Pirating a $7000 version of a million-dollar gene therapy
MIT Technology Review - 30-Aug-2019This could be beneficial if things go well, but dangerous otherwise
Salk scientists developed a new genome-editing tool tested on mice
Salk Institute - 23-Aug-2019New powerful tool is developed for targeting the non-coding areas of DNA
Human trials using CRISPR to cure genetically inherited blindness
Futurism - 30-Jul-2019There are at least 13 types of LCA - this trial is aimed at treating LCA 10
First attempt to use CRISPR tool to treat a genetic disorder
NPR - 29-Jul-2019Cells are being taken from patients' bone marrow and genetically modified with CRISPR
NHS gives the green-light to a “gene-silencing” drug for the first time
BBC - 09-Jul-2019It took thirteen years for RNA interference technology to come to this stage
Crispr injection could reduce chance of heart attack
Guardian - 10-May-2019Verve Therapeutics treatment targets PCSK9 gene
Interfering with enzyme production reduces crippling pain
BBC - 13-Apr-2019Gene silencing rather than gene therapy
Gene therapy makes non-vision cells light sensitive
University of California, Berkeley - 15-Mar-2019This would be a stunning result if repeated in humans
Human tissue regeneration possible with complete axolotl genome map
Gizmodo - 24-Jan-2019Understanding regeneration in axolotls will be a paradigm shift for medicine
New gene therapies having big impact
Guardian - 19-Jan-2019Successful treatment of retinitis pigmentosa and spinal muscular atrophy
What Happens When CRISPR Backfires?
Seeker - 25-Sep-2018Recent research revealed novel problems with the CRISPR technique, delaying human trials
Drug approved as alternative method to CRISPR
Singularity Hub - 21-Aug-2018Patisiran is a new drug capable of silencing genes based on RNA interference technology
Caution Regarding CRISPR Gene Therapies
Singularity Hub - 23-Jul-2018Newly found lack of precision of CRISPR delays plans for human trials
Gene therapy reverses rat's paralysis
BBC - 14-Jun-2018Study used virus to deliver genetic information that reduced scar tissue in the spinal cord
Gene Therapies to Greatly Reduce the Incidence of Cardiovascular Disease
Fight Aging! - 09-Mar-2018Gene therapy could disable genes that sustain levels of lipids in the bloodstream.
CRISPR Toolkit Expands With Trio of New Tricks
Singularity Hub - 27-Feb-2018New CRISPR technologies are CAMERA, DETECTR, and SHERLOCK.
Haemophilia A gene therapy results 'mind-blowing'
BBC - 14-Dec-2017Haemophilia prevents production of a protein needed to stop bleeding.
Gene Therapies as a Basis to Control Aging
Fight Aging! - 04-Dec-2017In principle, a gene therapy can do everything a drug can.
FDA Target Rogue Gene Therapy Clinics
New York Times - 16-Nov-2017FDA issued new guidelines for expedited review of stem cell and gene therapies.
First ever attempt at gene editing inside the body
Guardian - 15-Nov-2017Patient lacks a gene that makes an enzyme that breaks down certain carbohydrates.
Genetically modified skin in life-saving treatment
BBC - 08-Nov-2017Junctional epidermolysis bullosa DNA lacks the instructions to stick epidermis to the dermis.
17 new genes linked to longer lifespan identified
Times Now News - 08-Nov-2017A team of researchers have discovered 17 new genes linked to longer lifespan, which they say could one day be targeted to help prolong human life.
Scientists Discover a Key to a Longer Life in Male DNA
New York Times - 16-Jun-2017Growth hormone receptors is linked to an increase in life span of about 10 years among men.
Ageing is a Disease. Gene Therapy Could be the Cure
WIRED - 20-Apr-2017Most age related diseases are a symptom of cellular malfunction.
Gene therapy cures boy of sickle cell disease
New Scientist - 01-Mar-2017People with sickle cell disease make abnormal versions of haemoglobin – distorting red blood cells into a sickle-shape that can get stuck in blood vessels.
Qatar leading ‘ambitious’ genome project in Gulf
Gulf Times - 06-Jan-2017Qatar Genome Programme (QGP) focuses on mapping the population as well as treating common and rare diseases.
Possible way to stop activation of proteins known to cause age-related diseases
News Medical - 15-Dec-2016Scientists have discovered that it is possible to stop the activation of a group of proteins – NADPH Oxidase.
CRISPR Gene Editing Cures Mice of Sickle Cell Disease
Futurism - 12-Oct-2016CRISPR used to correct mutated hematopoietic stem cells.
Target Genes for Slowing Aging
Fight Aging! - 06-Jun-201675 potential targets for gene therapy in the near future.
Could mRNA Overtake all other Biologicals in Medicine?
Labiotech - 05-Jan-2016What if we could send the body an instruction to produce its own drug?
Genes that help you live to 100
New Scientist - 30-Dec-2015Searching the genomes of centenarians these genes are most clearly associated with lifespan.
Can we extend our lifespan, one gene at a time?
Genetic Literacy Project - 27-Oct-2015There are definitely environmental factors that influence longevity as well as genetic ones.
Gene therapy restores hearing in deaf mice
Kurzweil Network - 13-Jul-2015Targeted delivery of functioning TMC1 gene to hair cells in cochlea using engineered virus AAV1.
BioViva Moving Ahead With Human Gene Therapy for Telomerase Activation
Fight Aging! - 02-Apr-2015First company to treat a person with gene therapy to reverse biological aging.
