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Buck Institute

Independent biomedical research institute focused on aging

The Buck was a pioneer in research on aging, and now we’re a global leader in the field. We opened our doors in 1999, becoming the world’s only research institution singularly focused on the biology of aging, yielding insights into age-related diseases before they start. We hire scientists from a variety of disciplines to attack the problem from all sides because the answers we’re after won’t come from a single field. To enhance our process, we worked with world-renowned architect I.M. Pei to create a campus that literally would not allow our researchers to work in silos.

Visit website: https://www.buckinstitute.org/

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Details last updated 29-Aug-2019

Buck Institute is also referenced in the following:

BHB Therapeutics

Developing preventative medicines for age-related disease using ketone bodies

Napa Therapeutics

Focused on a novel target linked to one of the fundamental processes of aging

Selah Therapeutics

Company focused on novel ketone-based therapies for the treatment of heart diseases

Buck Institute Creations

SASP Atlas

Proteomic Atlas of SAS

People at Buck Institute

Judith Campisi

Professor of biogerontology and Biochemist.

Gordon Lithgow

Professor at The Buck Institute

Parminder Singh

Postdoctoral Research Fellow at Buck Institute for Research on Aging

Tara Tracy

Assistant professor at the Buck Institute for Research on Aging

Martin Brand

Professor at the Buck Institute for Research on Aging

Pankaj Kapahi

Education professional skilled in Research, Life Sciences, Genetics, Biochemistry, and Science

Birgit Schilling

Professor at Buck Institute for Research on Aging

David Furman

Director of the Buck Artificial Intelligence Platform & Stanford 1000 Immunomes Project

Lizellen La Follette

OBG-YN and Member Board Of Trustees at the Buck Institute for Research on Aging

Eric Verdin

CEO & President at Buck Institute for Research on Aging

Suzanne Angeli

Assistant Professor of Molecular & Cellular Biology, Lithgow lab, Buck Institute

Chuankai Zhou

Buck Fellow at Buck institute - studies mechanisms underlying the cellular aging process

Brianna Stubbs

Lead Translational Scientist at Buck Institute for Research on Aging

Jennifer Garrison

Assistant Professor and Co-Founder & Director of Global Consortium for Reproductive Longevity & Equality at Buck Institute

Bruce Barclay

New Zealand/British investor, entrepreneur and philanthropist

Julie Andersen

Professor at Buck Institute for Age Research.

Kenneth Wilson

Postdoctoral Researcher at Buck Institute for Research on Aging.

Simon Melov

Professor at Buck Institute for Research on Aging and CEO of Gerostate Alpha.

Heinrich Jasper

Professor at the Buck Institute for Research on Aging.

Chandani Limbad

Research scientist at Buck Institute for Research on Aging

John Newman

Geriatrician, basic science researcher, and educator at the Buck Institute and the UCSF

Christopher Wiley

Research Assistant Professor at Buck Institute for Research on Aging

Buck Institute News

Senolytic drugs offered mixed clues about their potential impact on ageing

Fight Aging! - 04-Mar-2024

While modifying immune cell populations, the drugs also increased ageing biomarkers

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A new method called FAST studies cellular ageing in cultured cells

Live Forever Club - 18-Jan-2024

FAST is precise and works with different cell types and microscopes

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Eating less activates the gene OXR1 which controls brain ageing and lifespan

Buck Institute - 11-Jan-2024

Research sheds light on the benefits of calorie restriction

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Fisetin in berries and apples could shield your heart in later years

Live Forever Club - 19-Dec-2023

Supplementation reduced the buildup of senescent cells in the arteries of aged mice

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Ageing eyes face a double whammy of senescent cells and weakened defenses

Live Forever Club - 19-Dec-2023

Senolytic intervention helps to repair the protective barrier of the eyes

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Buck Institute and Phenome Health team up to advance scientific wellness

Buck Institute - 27-Sep-2023

Collaboration of data and discovery to extend healthspan for everyone

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Mitochondria-targeted compound prevents and treats metabolic syndrome in mice

Buck Institute - 07-Jul-2023

Selectively inhibits problematic free radicals - potential breakthrough in treatment of chronic diseases & ageing

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Reason reports back from Age-Related Disease Therapeutics Summit 2023

Fight Aging! - 16-Jun-2023

Many people believe lots of clinical trials of novel therapeutics targeting mechanisms of aging will start up in the next few years

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Eye imaging can track the efficacy of interventions aimed at slowing the aging process

Buck Institute - 28-Mar-2023

Scans to know the eyeAge can provide an actionable evaluation of gero-protective therapeutics

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Lifespan.io summarises the proceedings of the Buck Institute's Longevity Summit

Lifespan.io (LEAF) - 20-Jan-2023

Another reminder of the amount of research, with multiple approaches, about to go into clinical trials

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Senolytics-a risky proposition in aging and repair mechanisms

Lifespan.io (LEAF) - 19-Oct-2022

The study is a caution for scientists engaging in self-experimentation with senolytics

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Reason reports back from October's Rejuvenation Startup Summit

Fight Aging! - 19-Oct-2022

Some really exciting developments with quite a few in clinical trials

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Racing for the lead... Underdog becomes Cyclarity Therapeutics

Longevity Technology - 20-Jun-2022

Also announces move to Buck Institute for Research on Aging

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Not just vision - diet and eye health is linked to aging in fruitflies

Buck Institute - 07-Jun-2022

Staring at gadget screens at night affects circadian clock and in turn lifespan

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Buck researchers discover mitochondrial protein that can increase lifespan

Buck Institute - 18-May-2022

In yeast, increasing Tom70 delays ageing related mitochondrial dysfunction

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Selah Therapeutics launched to focus on ketone-based therapies for heart disease

Longevity Technology - 13-May-2022

Treatment options for diseases of aging - from the makers of metabolic switch

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A natural cholesterol metabolite with senolytic effect in mice and humans

Buck Institute - 02-Feb-2022

New class of senotherapeutic drugs that could possibly target various diseases and ageing

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New study unveils the role of tau in neurodegenerative disease

Buck Institute - 20-Jan-2022

Interactions with mitochondrial & synaptic proteins highlight targets against Tau-mediated disease

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Complicated connection between protein shape and mitochondrial health, causing aging

Buck Institute - 07-Sep-2021

The “bad” process of pore opening and the “good” process of UPRmt - connection revealed

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Immune system clock tracks health, age-related disorders, and longevity

Buck Institute - 12-Jul-2021

Measuring immune health with a chemokine, CXCL9, for early disease interventions

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First ever non-invasive biomarker test to detect senolysis

Buck Institute - 02-Apr-2021

Detectible senescence-specific biomarker allows development of new drugs for age-related conditions

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Super summary of 3rd Annual Longevity Therapeutics Summit

Lifespan.io (LEAF) - 16-Feb-2021

More and more companies making greater and greater progress - 2021 could be an exciting year

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Gerostate Alpha looks at ageing in an unbiased way

Longevity Technology - 20-Jan-2021

Instead of targeting specific hallmarks/pillars - they want to target ageing as a whole

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A force of tissue stiffness could bring new changes to immune drugs

Buck Institute - 12-Jan-2021

Tissue stiffness alter immune system response to chronic diseases and ageing

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Chronic inflammation promotes NAD+ decline during aging

Buck Institute - 16-Nov-2020

Senescent cells induce NAD+ decline via activation of CD8 macrophages

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Body builder supplement AKG extends lifespan and healthspan of mice

Buck Institute - 01-Sep-2020

Blood levels fall with age. NUS planning a clinical trial with middle-aged humans.

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How lamins are linked to senescence and ageing

Lifespan.io (LEAF) - 19-Jun-2020

Connections have been elucidated but more research needed to confirm significant links

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Eating less to live longer? Study in fruit fly finds no benefit

Science Daily - 04-Jun-2020

Life extending benefit of dietary restriction might depend upon genetic makeup

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Comprehensive history and explanation of senescent cells

The Scientist - 01-Mar-2020

Including the latest on clinical trials of first-generation senolytics

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Underlying mechanisms of how cellular senescence leads to neurodegeneration

Buck Institute - 29-Jan-2020

Cellular senescence is now a top research topic and a very messy one in ageing research

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SASP Atlas created by team of researchers

Lifespan.io (LEAF) - 28-Jan-2020

It is a comprehensive proteomic database of soluble proteins and exosomal cargo SASP factors

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Can we treat the ageing process or not? That's the question

UCSF - 02-Jan-2020

John Newman, UCSF asst prof & Buck Institute researcher, explains upcoming ageing interventions

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Longevity Leaders' latest report on how longevity is disrupting the world

Longevity Leaders (LSX) - 01-Jan-2020

An interesting collection of interviews and white-papers with industry leaders

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Longevity.Technology interviews Buck Institute’s President and CEO Eric Verdin

Longevity Technology - 03-Oct-2019

Includes updates on NAPA Therapeutics and BHB Therapeutics

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Senolytics for IPF human clinical trial results released

Lifespan.io (LEAF) - 07-Jan-2019

Physical improvements recorded, but pulmonary function was unchcanged

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Aging focused biotechs forms AI based joint venture

FierceBiotech - 14-Aug-2018

Groundbreaking research biotechs performs aging research together for longevity

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SRF has made progress in the fight against ageing

Lifespan.io (LEAF) - 05-Dec-2017

R&D phase in SENS repair approach has shown promising results

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Metformin human trials planned

Diabetes.co.uk - 30-Nov-2015

Could significantly increase life expectancy and health span. 20 years ago aging was a biologica...

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Switching off genes could extend lifespan by 60 per cent

Sydney Morning Herald - 12-Oct-2015

238 genes identified that, when silenced, increase the lifespan of yeast cells. Half of these ge...

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Lifespan-extending drug given late in life reverses age-related heart disease in mice

Kurzweil Network - 12-Jun-2013

Elderly mice suffering from age-related heart disease saw a significant improvement in cardiac fu...

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Topics mentioned on this page:
Ageing Research