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John Newman

Geriatrician, basic science researcher, and educator at the Buck Institute and the UCSF

As a physician-scientist, Dr. Newman hopes to translate what we are learning of the pathways that control fundamental mechanisms of aging into therapies that will improve the health and preserve the independence of older adults.
His research work as an Assistant Professor at the Buck Institute, in sunny Novato, focuses on how ketone bodies, small molecules that our bodies make for energy when we fast or exercise, also act as molecular signals to control inflammation and gene expression. The signaling functions of ketone bodies may be translational targets for protecting cognition and improving resilience in older adults. This is one example how environmental cues like diet and fasting signal through small metabolites in our cells to regulate the genes and pathways that in turn control aging. Dr. Newman is particularly interested in testing if harnessing these signals can protect older adults from the risks of hospitalization like delirium and functional decline.

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See also: Institute Buck Institute - Independent biomedical research institute focused on aging

Details last updated 26-Jan-2020

John Newman is also referenced in the following:

Investing in the Future of Longevity – the Ketone Chapter


Juvenescence webinar about the latest research and developments on future of longevity investment

Targeting Metabesity 2022

10-Oct-2022 to 13-Oct-2022

The Kitalys Institute virtual conference about going beyond treating individual diseases to extending healthy lifespan

John Newman News

Selah Therapeutics launched to focus on ketone-based therapies for heart disease

Longevity Technology - 13-May-2022

Treatment options for diseases of aging - from the makers of metabolic switch


Can we treat the ageing process or not? That's the question

UCSF - 02-Jan-2020

John Newman, UCSF asst prof & Buck Institute researcher, explains upcoming ageing interventions