Buck researchers discover mitochondrial protein that can increase lifespan
Buck Institute - 18-May-2022In yeast, increasing Tom70 delays ageing related mitochondrial dysfunction
Join the club for FREE to access the whole archive and other member benefits.
Buck Fellow at Buck institute - studies mechanisms underlying the cellular aging process
Fellow at Buck institute and focuses on understanding the plasticity and homeostasis of the cellular proteome under stress conditions and aging.
The Zhou lab studies mechanisms underlying the cellular aging process, with a particular emphasis on proteostasis. They study protein folding and misfolding in both young and aging cells, with the goal of understanding the events that lead to the loss of proteostasis during cellular aging and disease as well as identifying mechanisms that can be exploited to rejuvenate aging cells. Their lab uses the budding yeast Saccharomyces cerevisiae to study these topics systematically and comprehensively at the molecular and cellular levels. Budding yeast has been proven to be a great model system for research on cellular aging and revealed longevity mechanisms that are highly conserved in metazoan. By leveraging genetic tools and libraries, they hope to progress quickly on projects to provide insights for fundamental biological questions. They are also developing new methodologies and platforms to broaden their technology portfolio that can be unleashed to break through current limitations in the field and improve our understanding of aging and age-related diseases.
Visit website: https://www.buckinstitute.org/lab/zhou-lab/
See also: Buck Institute - Independent biomedical research institute focused on aging
Details last updated 22-Jun-2022
In yeast, increasing Tom70 delays ageing related mitochondrial dysfunction