Study reveals surprising telomere loss patterns in calorie restricted humans

Pennsylvania State University (PSU) - 17-Apr-2024

Complexities spark hope for health benefits beyond telomere length

Telomeres are different lengths than scientists previously thought

Phys.org - 11-Apr-2024

This could transform how we approach diseases linked to cell ageing

Telomere-based interventions offer promising avenues for combating ageing

Live Forever Club - 23-Feb-2024

Telomere research is in its early stages, with much to be discovered

Green neighborhoods linked to longer lives and slower ageing

The Guardian - 01-Dec-2023

Every 5% increase in green space adds 1% younger cells to your body

New mice with human-like telomeres could help us fight ageing and cancer

The Jerusalem Post - 30-Oct-2023

Model could be used to study the role of telomere length in several diseases

Regular jogging or running could help to keep cells younger and healthier

Live Forever Club - 26-Oct-2023

Jogging or running for at least 75 minutes per week linked to longer telomeres

Rejuvenation Technologies raises $10.6M to develop anti-ageing therapies

Longevity Technology - 07-Sep-2023

A single dose of mRNA therapy could rewind ageing and extend lifespan

Telos Biotech parent, Cambrian Bio, to develop robust cell therapies for treating age-related diseases

Longevity Technology - 27-Jun-2023

Novel recombinant protein to manufacture biologically fit cells by safely lengthening telomeres

Summary of Fabrizio d’Adda di Fagagna presentation at Longevity Med Summit

Live Forever Club - 18-May-2023

Telomeres become sinks of irreparable damage - antisense oligonucleotides could potentially provide a fix

Telomere length may have protective effects against dementia-provide a pathway for future research

Oxford Population Health - 22-Mar-2023

Associations between telomere length and endophenotypes could help treat neurodegenerative disease

Telomeres encode two novel signaling proteins may change our understanding of cancer and aging

Phys.org - 20-Feb-2023

Blood tests for proteins encoded by telomeres could give information of biological age and cancer

Telocyte secures new investment, taking telomerase gene therapy to the clinic in CVD and more

Longevity Technology - 03-Feb-2023

The researchers will not only focus on CVD or cellular aging but the optimal point of intervention

Researchers found a missing genetic link that helps melanoma cells defeat mortality

EurekAlert! - 10-Nov-2022

Mutations in a telomere binding protein provide a new approach to treat melanoma and other cancers

Excessive alcohol consumption may age you faster by accelerating your biological age

Interesting Engineering - 28-Jul-2022

Alcohol consumption causes telomere shortening, leading to several age-related diseases

New insight on the accumulation of senescent cells in humans

UPMC - 30-Jun-2022

Oxidative DNA damage induce rapid senescence compared with shorter telomeres from repeated cell divisions

Lifespan of middle-aged mice increased by a third with telomerase gene therapy

CISION PR Newswire - 19-May-2022

Treatment used proprietary CMV vector which is able to deliver multiple genes into the nucleus

Viral-vector gene therapies could unlock healthy life extension in humans

Lifespan.io (LEAF) - 12-May-2022

Lifespan of mice greatly extended even when treatment only started at the equivalent of 56 years old

Faster walking associated with longer telomeres, could improve health and lifespan

Lifespan.io (LEAF) - 11-May-2022

We know exercise keeps people healthier and this may be just one of the underlying mechanisms

New study where biological age reduces as chronological age increases

Bioviva Science - 18-Nov-2021

Evident reversal of Dementia symptoms sustained cognitive improvement

A new model enter into telomere-mediated senescence to reduce genome damage

Genetic Engineering & Biotechnology News (GEN) - 10-Nov-2021

Telomeres repair can prevent senescence and genome instability

Biobank study: People with longer telomeres live 2.5 years longer

Lifespan.io (LEAF) - 13-Oct-2021

New insights into the genetic regulation of leukocyte telomere length

Activation of telomerase gene prevents aging in certain types of cells

EurekAlert! - 23-Jul-2021

DNA region: VNTR2-1 plays a role in human aging and tumorigenesis

Bigmouth buffalo fish can live up to 112 years with no signs of ageing

Lifespan.io (LEAF) - 06-May-2021

Long-living fish gives key insights on evolution history to age slower and live longer

BioViva tests experimental telomerase gene-therapy in 6 Alzheimer's patients

Biospace - 03-May-2021

Launched home test to track biological age; outcomes of unlicensed gene-therapy are yet to report

Atomic structure of human telomerase developed using cryo-electron microscopy

Phys.org - 22-Apr-2021

High resolution telomerase model revealed new protein subunits; promises new therapy for aging diseases

Body's own drug, spermidine prevents age-related pathologies

Innovation Origins - 23-Feb-2021

Spermidine supplemented mice showed anti-ageing effects by preserving telomere length

Fraility maybe a better marker for ageing than telomere length

Longevity Technology - 07-Jan-2021

Telomere length may not be an accurate indicator of lifespan & health in the elderly

Stem cells protect chromosomal ends differently than normal cells

The University of Sydney - 26-Dec-2020

Insights on this unique strategy could have breakthrough treatments for ageing and many diseases

Telomere shortening - a new milestone in cancer therapy

Medical News Today - 25-Dec-2020

Shortening telomere length in cancerous cells will prevent them from dividing

A mushroom compound that could prevent telomere shortening

NutraIngredients-USA - 14-Dec-2020

Antioxidant ergothioneine alleviates harmful effects of oxidative stress on telomere length

Study supports link between ageing, telomere length & cancer

New Atlas - 02-Dec-2020

Telomere shortening might be a protective measure to ward off cancers as we age

Oxygen therapy reversed the human age biologically

YAHOO! - 18-Nov-2020

Not as easy as taking a pill, but a stunning result on both telomeres and senescent cells

NAD precursor could prevent telomere loss

Longevity Technology - 04-Nov-2020

Restoring NAD homeostasis could help in ageing diseases with telomere dysfunction

Mechanism underlying telomere restoration in T cells discovered

Lifespan.io (LEAF) - 20-Oct-2020

Telomere transfer from APCs boosts T cells lifespan-helpful in immunosenescence

New discovery explains mechanism regulating telomere length and function

Phys.org - 13-Oct-2020

Now we can better understand processes that regulate cell survival in ageing

New technique to measure individual telomere lengths in 3 hours

Phys.org - 25-Sep-2020

Not just average length that is important, so full profile provides more clinical uses

Eating junk food could make you age faster

ScienceAlert - 01-Sep-2020

Study finds link between ultra processed food and shorter telomeres

Telomerase gene therapy prevents age-related lung fibrosis in mice

Pulmonary Fibrosis News - 19-Aug-2020

Could pave way for preventing the disease in humans and improve healthspan

A step closer to reversing pulmonary fibrosis via telomerase gene therapy

Lifespan.io (LEAF) - 12-Aug-2020

Study in mice revealed great progress and potential for curing fibrotic diseases in humans

Mindfulness meditation prevents shortening of telomeres

Psych Central - 27-Jul-2020

Only a small study (17 meditators) but interesting nonetheless

Telomerase activity restored in vitro and in mice

Lifespan.io (LEAF) - 27-Apr-2020

Potential to support new therapies for dyskeratosis congenita, other age-related diseases

Discovery of molecules allowing telomere restoration

New Atlas - 26-Apr-2020

Demonstrated in mice, study paves way for treating ageing-related diseases

Rapamycin decreased survival and longevity in mice with short telomeres

Phys.org - 03-Mar-2020

mTOR, a pro-survival pathway for shorter telomeres and inhibition is deleterious

Human trials to test efficacy and safety of genetic introduction of telomerase

Genome Context - 23-Nov-2019

Telomeres: are we about to crack the secrets of anti-ageing

Dr. Michael Fossel interviewed by LEAF

Lifespan.io (LEAF) - 18-Nov-2019

Fossel argues for telomerase therapy over senolytics

Mice with extra-long telomeres lived longer

ScienceAlert - 21-Oct-2019

Will we be able to have a longer lifespan by lengthening our telomeres too?

Don't hurry to predict your longevity with biomarkers

The Scientist - 27-Sep-2019

Longevity results can be unproven and not ready in some aspects for being used in clinics

Telomere length linked to the nervous system

Medical Xpress - 26-Sep-2019

According to the study, shortening in the telomere length have reflected in our brain structure

Michael West examines how to safely revive telomerase

Lifespan.io (LEAF) - 12-Sep-2019

It powers foetal development and telomere length, but also cancers

Leukocyte telomere length found to be linked to DNA methylation (DNAm)

News Medical - 02-Sep-2019

Yet more evidence that hallmarks of ageing are inter-related, not standalone actions

Pluripotency and telomeres, butterfly effect discovered

ScienceDaily - 20-Aug-2019

Pluripotent cells are like a black box, but they can open new doors for regenerative medicine

Longer telomeres linked to reduced risk of psychiatric problems in men

Oxford University Press - 05-Jun-2019

But telomere length is not linked to overall multimorbidity

Telomerase therapy for neurodegeneration

Lifespan.io (LEAF) - 04-Jun-2019

Telomerase gene therapy may be a potential solution for age-related neurodegenerative diseases

Direct oxidative stress on telomeres leads to faster cellular ageing

News Medical - 14-May-2019

Prevents uncontrolled cell division in cancer cells

Environmental pollutants in household items can affect ageing

INVERSE - 02-May-2019

Reduces length of telomeres and alters mitochondrial DNA levels in cells

New telomeres lengthening treatment - space flight!

Independent - 11-Apr-2019

Unfortunately the effect disappears after returning to Earth

Exercise lengthens telomeres (slows aging)

NHS - 29-Nov-2018

Endurance and interval training groups saw telomeres increase by over 3%.

2018 Telomere Length Update by Liz Parrish

Bioviva Science - 24-Sep-2018

A case of muscular and cellular rejuvenation thanks to myostatin and telomerase therapies

Telomerase Gene Therapy Does Not Increase Cancer Risk

Lifespan.io (LEAF) - 27-Aug-2018

New research proves telomerase therapy's safety by making its effects within the cell temporary

Telomere loop structure more important than length

Medical Xpress - 20-Jul-2018

Telomere structure rather than length may be the key to prevent aging

Telomerase: Downgraded by long term proponent

Josh Mitteldorf Blog - 19-Mar-2018

Motherhood Causes 11 Years of Telomere Shortening

ScienceAlert - 26-Feb-2018

Long-Lived Bats Have Telomeres That Don't Shorten

INVERSE - 07-Feb-2018

Telomeres Do Not Translate Into A Younger Biologic Age

Institute For Aging Research - 31-Jan-2018

Prenatal pollution exposure linked to decreased telomere length

2 Minute Medicine - 25-Oct-2017

Direct correlation between telomere length and heart failure found

Medical Xpress - 07-Sep-2017

Josh Mitteldorf argues against long telomeres causing cancer

Josh Mitteldorf Blog - 23-Aug-2017

Research holds Promise for Future Clinical Therapies to Slow Aging

Next Big Future - 01-Aug-2017

Scientists Discover Master Regulator of Cellular Aging

Scripps Research Institute - 12-Jan-2017

Poor Correlation Between Telomere Length and Health

Fight Aging! - 02-Sep-2016

Telomere Length Does Not Predict Atherosclerosis Risk

Fight Aging! - 25-May-2016

Impatient People Likely To Age Faster

Tech Times - 24-Feb-2016

How Long Will You Live?

Veritasium - 25-Nov-2015

Telomeres naturally shorten each time DNA is copied in preparation for cell division

Kurzweil Network - 13-Nov-2015

Alpha lipoic acid lengthens telomeres

Emory University - 20-Aug-2015

Telomere Length and Mortality

Humanity+ - 04-May-2015

Telomere extension turns back aging clock in cultured human cells

Stanford University - 22-Jan-2015

Telomerase “off” switch discovered; stops cells dividing indefinitely

Salk Institute - 19-Sep-2014