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Aging Cell

Scientific Journal devoted to age related diseases.

Aging Cell is a bi-monthly peer-reviewed, open access journal that aims to publish the highest quality, innovative research addressing fundamental issues in the biology of aging. For publication in Aging Cell, the work must provide a major new contribution to the understanding of aging and be of general interest to the community. Aging Cell seeks to cover all areas of geroscience, highlighting research that uncovers mechanistic aspects of the aging process, as well as the links between aging and age-related disease. Observations of novel aging processes without substantial mechanistic insight will be considered, but should be of especially high impact for the field. Topics including, but not limited to, nutrient-responsive signaling pathways, neuronal and endocrine signaling pathways, tissue interactions, genetic and epigenetic regulation and integrity, proteostasis, circadian rhythms, ROS and mitochondria, cellular senescence, stem cells, progerias and interventions that affect aging are encouraged.

Visit website: https://onlinelibrary.wiley.com/journal/14749726

 AgingCell

See also: Publisher Wiley Online Library - Subscription-based library that is a collection of online resources covering life, health and physical sciences

Details last updated 09-Nov-2019

Aging Cell News

Blood test decodes your aging clock: metabolites hold the key to staying young

UPMC - 11-Mar-2024

New discovery unveils a molecular fingerprint to predict biological age

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Transplanted cells age at different rates depending on the host's age

Live Forever Club - 05-Mar-2024

Bodies of younger people could potentially rejuvenate older transplanted cells

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Senolytic drugs offered mixed clues about their potential impact on ageing

Fight Aging! - 04-Mar-2024

While modifying immune cell populations, the drugs also increased ageing biomarkers

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A new way to understand ageing by looking at how DNA is organized in our cells

Live Forever Club - 21-Feb-2024

The approach may lead to earlier disease detection & better treatments

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Fisetin in berries and apples could shield your heart in later years

Live Forever Club - 19-Dec-2023

Supplementation reduced the buildup of senescent cells in the arteries of aged mice

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SIRT2 overexpression does not significantly impact lifespan in mice

Live Forever Club - 05-Dec-2023

Study suggests a more nuanced role of this protein in the ageing

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Mechanical reprogramming enhances fibroblast function for skin rejuvenation

Lifespan.io (LEAF) - 04-Dec-2023

The method enhances their abilities and promotes wound healing in aged skin

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Eating less, living longer: the positive effects of calorie restriction

International Institute on Ageing (INIA) - 16-Oct-2023

Modest calorie reduction can activate genes for healthy ageing

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Metformin may minimize muscle loss in extended periods of bed rest

Lifespan.io (LEAF) - 24-Jul-2023

Improvements seen in muscle size and collagen deposits in older people with atrophy

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Use of rilmenidine drug showed lifespan and healthspan benefits in both young and old animals

Longevity Technology - 25-Jan-2023

With a global ageing population, the benefits of delaying ageing, even if slightly, are immense

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Reprogramming by cellular rejuvenation in mice increases lifespan and health

Lifespan.io (LEAF) - 01-Nov-2022

Partial reprogramming extends healthspan and lifespan by single or lifelong treatment

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Metformin misinterpreted as antiaging drug via animal studies, TAME heads for future trials

SENS Research Foundation - 04-Oct-2022

More than 90% of drugs safe and effective when tested in experimental animals fail in human testing

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Urolithin A can increase mitochondrial health in living joint tissue and improved mobility

Business Wire - 07-Jul-2022

Mitopure can improve mitochondrial health and counteract age-related muscle function decline

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CD38 inhibitor increases lifespan and fitness in male mice

Lifespan.io (LEAF) - 05-Apr-2022

New anti-ageing approach to ramp up NAD levels and life extension

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Senolytics promotes wound healing in the aged but not in young mice

Lifespan.io (LEAF) - 22-Dec-2021

Dasatinib plus quercetin slow down muscle regeneration in young mice

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Hyperactivation of senescent cells can trigger cytokine storm

Lifespan.io (LEAF) - 13-Aug-2021

Stimulated senescent human umbilical vein cells showed high susceptibility to inflammatory diseases

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Extracellular matrix gene expression: a novel approach to find geroprotective drugs

Lifespan.io (LEAF) - 11-Aug-2021

ECM reprogramming to identify drugs which can slow-down or prevent age-related diseases

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Clearing out aged cells with senolytics can relieve jaw pain

University of Connecticut (UConn) - 07-Jul-2021

Senolytics for cartilage and bone regeneration in jaw joints, proven effective in mice

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A 12-week strength-endurance training lowered senescence proteins in older people

Lifespan.io (LEAF) - 14-Jun-2021

New study using biomarkers proved the importance of regular exercise again

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2021 NIA's lifespan extension study results on mice out now

Longevity Technology - 01-Apr-2021

Longer lifespan in old male mice treated with 17‐α‐estradiol, but four other compounds had no effect

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Boosting NAD+ levels with NR reverted symptoms of premature ageing disease

Lifespan.io (LEAF) - 31-Mar-2021

Benefits in older mice, but NR treatment in young mice increased inflammation and DNA damage

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Rapamycin might not be an alternative for calorie restriction

Lifespan.io (LEAF) - 27-Jan-2021

Failed to mimic dietary restriction pathways on extending lifespan in progeroid mice

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Whole-body senescent cell removal improved brain health in mice

Lifespan.io (LEAF) - 22-Jan-2021

Senolytic drug and cancer drug with quercetin improved age-related cognition

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Ageless Rx to investigate role of Rapamycin in human longevity

Longevity Technology - 12-Nov-2020

Set to launch Participatory Evaluation of Aging with Rapamycin for Longevity (PEARL) trial

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OTC drug Ibuprofen could reverse age associated inflammation

Longevity Technology - 06-Nov-2020

A study on mice supported ibuprofen for use in neurodegenerative diseases

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Middle-aged mice live 10% longer with 4 days of CASIN injections

Lifespan.io (LEAF) - 14-Aug-2020

It would be interesting to see how long they lived with regular treatment through old-age

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Low stress hormone levels promotes premature ageing

Longevity Technology - 11-Aug-2020

Balance is key to everything especially with human body

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Regulatory role of GDF 15 related to ageing and metabolism in humans and mice

Longevity Technology - 06-Aug-2020

Discovery of this homeostatic function just may be the first step but it looks promising

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Longitudinal DNA methylation is influenced by genetic, environmental factors

Longevity Technology - 03-Aug-2020

Decade-long studies of identical twins were able to reveal connections

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Low cortisol levels can trigger 'macrophaging'

Medical Xpress - 01-Jul-2020

Learning this age-induced disruption of macrophage functions powers pharmaceutical research

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Navitoclax improved, now a safer senolytic drug choice

Fight Aging! - 09-Apr-2020

They found efficient way to increase its senolytic specificity, reduce platelet toxicity

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Ageing in mice - the systemic burden of senescent cells matters

Fight Aging! - 06-Feb-2020

Senescent cell burden is a marker of disease free years ahead of life

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Treating with rapamycin improves blood flow to the brain in rats

Science Daily - 06-Nov-2019

Blood circulation in the brain didn't deteriorate even a bit for 15 months

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Biological age reversed with growth hormone and diabetes drugs cocktail

Nature - 05-Sep-2019

Small, uncontrolled trial, but (potentially) very exciting results

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It's time for considering drug-exercise interactions

New York Times - 19-Jun-2019

Interesting - metformin plus exercise did not have an additive effect

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Right time to adopt "anti-ageing" lifestyle

News Medical - 07-Jun-2019

Key molecular programs known to promote longevity do not last beyond midlife

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NR boosts intestinal stem cell population in aged mice

MIT - 28-Mar-2019

Supplement has a real physical health impact too = reduced inflammation

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Nucleosome spacing of cell-free DNA reveals biological age

News Medical - 21-Dec-2018

Always good to find a new biomarker of aging

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Reversing aging by removing wrinkles inside our cells

ScienceDaily - 29-May-2018

Virus-based treatment seeks to smooth cellular wrinkles in livers

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Low-calorie diet prevents age-related molecular changes

Medical Xpress - 25-May-2018

Short-term diets may accelerate the manifestation of aging symptoms

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Exercise in old age prevents immune system from declining

BBC - 08-Mar-2018

Cyclists in their 80s had the immune systems of 20-year-olds. Immune system decline makes older ...

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Inhibition of ageing maybe the solution for Alzheimer's

The San Diego Union-Tribune - 19-Jan-2018

Will be successful than drugs targeting specific aspects of Alzheimer's

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MCP-1 A Potential Aging Biomarker

Lifespan.io (LEAF) - 08-Jan-2018

Reliable and fast ways to assess biological age are needed to determine the outcome of potential ...

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Young Plasma Improves Cell Recycling in Old Rats

Fight Aging! - 11-Dec-2017

Injections of blood plasma from young rats improved autophagy and liver function in old rats. A...

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Scientists uncover changes in mRNA expression with ageing

Wiley Online Library - 17-Oct-2017

Accelerated ageing increases all-cause mortality at a molecular level

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Aging not inevitable for sea urchins

MDI Biological Laboratory - 24-May-2016

Sea urchins can quickly regrow damaged spines and feet. MDI Biological Laboratory studying sea u...

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Senolytics, A New Class Of Drugs, Slows Aging Process

Medical Daily - 11-Mar-2015

Senolytics, a new class of drugs, might dramatically slow the aging process and so change the fac...

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Lifespan-extending drug given late in life reverses age-related heart disease in mice

Kurzweil Network - 12-Jun-2013

Elderly mice suffering from age-related heart disease saw a significant improvement in cardiac fu...

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Topics mentioned on this page:
Ageing Research