Aging Cell
Scientific Journal devoted to age related diseases.
Aging Cell is a bi-monthly peer-reviewed, open access journal that aims to publish the highest quality, innovative research addressing fundamental issues in the biology of aging. For publication in Aging Cell, the work must provide a major new contribution to the understanding of aging and be of general interest to the community. Aging Cell seeks to cover all areas of geroscience, highlighting research that uncovers mechanistic aspects of the aging process, as well as the links between aging and age-related disease. Observations of novel aging processes without substantial mechanistic insight will be considered, but should be of especially high impact for the field. Topics including, but not limited to, nutrient-responsive signaling pathways, neuronal and endocrine signaling pathways, tissue interactions, genetic and epigenetic regulation and integrity, proteostasis, circadian rhythms, ROS and mitochondria, cellular senescence, stem cells, progerias and interventions that affect aging are encouraged.
Visit website: https://onlinelibrary.wiley.com/journal/14749726
See also: Wiley Online Library - Subscription-based library that is a collection of online resources covering life, health and physical sciences
Details last updated 09-Nov-2019
Aging Cell News
Blood test decodes your aging clock: metabolites hold the key to staying young
UPMC - 11-Mar-2024
New discovery unveils a molecular fingerprint to predict biological age
Read more...Transplanted cells age at different rates depending on the host's age
Live Forever Club - 05-Mar-2024
Bodies of younger people could potentially rejuvenate older transplanted cells
Read more...Senolytic drugs offered mixed clues about their potential impact on ageing
Fight Aging! - 04-Mar-2024
While modifying immune cell populations, the drugs also increased ageing biomarkers
Read more...A new way to understand ageing by looking at how DNA is organized in our cells
Live Forever Club - 21-Feb-2024
The approach may lead to earlier disease detection & better treatments
Read more...Fisetin in berries and apples could shield your heart in later years
Live Forever Club - 19-Dec-2023
Supplementation reduced the buildup of senescent cells in the arteries of aged mice
Read more...SIRT2 overexpression does not significantly impact lifespan in mice
Live Forever Club - 05-Dec-2023
Study suggests a more nuanced role of this protein in the ageing
Read more...Mechanical reprogramming enhances fibroblast function for skin rejuvenation
Lifespan.io (LEAF) - 04-Dec-2023
The method enhances their abilities and promotes wound healing in aged skin
Read more...Eating less, living longer: the positive effects of calorie restriction
International Institute on Ageing (INIA) - 16-Oct-2023
Modest calorie reduction can activate genes for healthy ageing
Read more...Metformin may minimize muscle loss in extended periods of bed rest
Lifespan.io (LEAF) - 24-Jul-2023
Improvements seen in muscle size and collagen deposits in older people with atrophy
Read more...Use of rilmenidine drug showed lifespan and healthspan benefits in both young and old animals
Longevity Technology - 25-Jan-2023
With a global ageing population, the benefits of delaying ageing, even if slightly, are immense
Read more...Reprogramming by cellular rejuvenation in mice increases lifespan and health
Lifespan.io (LEAF) - 01-Nov-2022
Partial reprogramming extends healthspan and lifespan by single or lifelong treatment
Read more...Metformin misinterpreted as antiaging drug via animal studies, TAME heads for future trials
SENS Research Foundation - 04-Oct-2022
More than 90% of drugs safe and effective when tested in experimental animals fail in human testing
Read more...Urolithin A can increase mitochondrial health in living joint tissue and improved mobility
Business Wire - 07-Jul-2022
Mitopure can improve mitochondrial health and counteract age-related muscle function decline
Read more...CD38 inhibitor increases lifespan and fitness in male mice
Lifespan.io (LEAF) - 05-Apr-2022
New anti-ageing approach to ramp up NAD levels and life extension
Read more...Senolytics promotes wound healing in the aged but not in young mice
Lifespan.io (LEAF) - 22-Dec-2021
Dasatinib plus quercetin slow down muscle regeneration in young mice
Read more...Hyperactivation of senescent cells can trigger cytokine storm
Lifespan.io (LEAF) - 13-Aug-2021
Stimulated senescent human umbilical vein cells showed high susceptibility to inflammatory diseases
Read more...Extracellular matrix gene expression: a novel approach to find geroprotective drugs
Lifespan.io (LEAF) - 11-Aug-2021
ECM reprogramming to identify drugs which can slow-down or prevent age-related diseases
Read more...Clearing out aged cells with senolytics can relieve jaw pain
University of Connecticut (UConn) - 07-Jul-2021
Senolytics for cartilage and bone regeneration in jaw joints, proven effective in mice
Read more...A 12-week strength-endurance training lowered senescence proteins in older people
Lifespan.io (LEAF) - 14-Jun-2021
New study using biomarkers proved the importance of regular exercise again
Read more...2021 NIA's lifespan extension study results on mice out now
Longevity Technology - 01-Apr-2021
Longer lifespan in old male mice treated with 17‐α‐estradiol, but four other compounds had no effect
Read more...Boosting NAD+ levels with NR reverted symptoms of premature ageing disease
Lifespan.io (LEAF) - 31-Mar-2021
Benefits in older mice, but NR treatment in young mice increased inflammation and DNA damage
Read more...Rapamycin might not be an alternative for calorie restriction
Lifespan.io (LEAF) - 27-Jan-2021
Failed to mimic dietary restriction pathways on extending lifespan in progeroid mice
Read more...Whole-body senescent cell removal improved brain health in mice
Lifespan.io (LEAF) - 22-Jan-2021
Senolytic drug and cancer drug with quercetin improved age-related cognition
Read more...Ageless Rx to investigate role of Rapamycin in human longevity
Longevity Technology - 12-Nov-2020
Set to launch Participatory Evaluation of Aging with Rapamycin for Longevity (PEARL) trial
Read more...OTC drug Ibuprofen could reverse age associated inflammation
Longevity Technology - 06-Nov-2020
A study on mice supported ibuprofen for use in neurodegenerative diseases
Read more...Middle-aged mice live 10% longer with 4 days of CASIN injections
Lifespan.io (LEAF) - 14-Aug-2020
It would be interesting to see how long they lived with regular treatment through old-age
Read more...Low stress hormone levels promotes premature ageing
Longevity Technology - 11-Aug-2020
Balance is key to everything especially with human body
Read more...Regulatory role of GDF 15 related to ageing and metabolism in humans and mice
Longevity Technology - 06-Aug-2020
Discovery of this homeostatic function just may be the first step but it looks promising
Read more...Longitudinal DNA methylation is influenced by genetic, environmental factors
Longevity Technology - 03-Aug-2020
Decade-long studies of identical twins were able to reveal connections
Read more...Low cortisol levels can trigger 'macrophaging'
Medical Xpress - 01-Jul-2020
Learning this age-induced disruption of macrophage functions powers pharmaceutical research
Read more...Navitoclax improved, now a safer senolytic drug choice
Fight Aging! - 09-Apr-2020
They found efficient way to increase its senolytic specificity, reduce platelet toxicity
Read more...Ageing in mice - the systemic burden of senescent cells matters
Fight Aging! - 06-Feb-2020
Senescent cell burden is a marker of disease free years ahead of life
Read more...Treating with rapamycin improves blood flow to the brain in rats
Science Daily - 06-Nov-2019
Blood circulation in the brain didn't deteriorate even a bit for 15 months
Read more...Biological age reversed with growth hormone and diabetes drugs cocktail
Nature - 05-Sep-2019
Small, uncontrolled trial, but (potentially) very exciting results
Read more...It's time for considering drug-exercise interactions
New York Times - 19-Jun-2019
Interesting - metformin plus exercise did not have an additive effect
Read more...Right time to adopt "anti-ageing" lifestyle
News Medical - 07-Jun-2019
Key molecular programs known to promote longevity do not last beyond midlife
Read more...NR boosts intestinal stem cell population in aged mice
MIT - 28-Mar-2019
Supplement has a real physical health impact too = reduced inflammation
Read more...Nucleosome spacing of cell-free DNA reveals biological age
News Medical - 21-Dec-2018
Always good to find a new biomarker of aging
Read more...Reversing aging by removing wrinkles inside our cells
ScienceDaily - 29-May-2018
Virus-based treatment seeks to smooth cellular wrinkles in livers
Read more...Low-calorie diet prevents age-related molecular changes
Medical Xpress - 25-May-2018
Short-term diets may accelerate the manifestation of aging symptoms
Read more...Exercise in old age prevents immune system from declining
BBC - 08-Mar-2018
Cyclists in their 80s had the immune systems of 20-year-olds. Immune system decline makes older ...
Read more...Inhibition of ageing maybe the solution for Alzheimer's
The San Diego Union-Tribune - 19-Jan-2018
Will be successful than drugs targeting specific aspects of Alzheimer's
Read more...MCP-1 A Potential Aging Biomarker
Lifespan.io (LEAF) - 08-Jan-2018
Reliable and fast ways to assess biological age are needed to determine the outcome of potential ...
Read more...Young Plasma Improves Cell Recycling in Old Rats
Fight Aging! - 11-Dec-2017
Injections of blood plasma from young rats improved autophagy and liver function in old rats. A...
Read more...Scientists uncover changes in mRNA expression with ageing
Wiley Online Library - 17-Oct-2017
Accelerated ageing increases all-cause mortality at a molecular level
Read more...Aging not inevitable for sea urchins
MDI Biological Laboratory - 24-May-2016
Sea urchins can quickly regrow damaged spines and feet. MDI Biological Laboratory studying sea u...
Read more...Senolytics, A New Class Of Drugs, Slows Aging Process
Medical Daily - 11-Mar-2015
Senolytics, a new class of drugs, might dramatically slow the aging process and so change the fac...
Read more...Lifespan-extending drug given late in life reverses age-related heart disease in mice
Kurzweil Network - 12-Jun-2013
Elderly mice suffering from age-related heart disease saw a significant improvement in cardiac fu...
Read more...