Telomir-1 study breakthrough: reversing ageing and extending lifespan
Telomir Pharmaceuticals - 21-Nov-2024Pioneering advancements offer hope for age-related therapies and improved quality of life
Telomeres News Archive
Astragalus-based supplement boosts telomere length in middle-aged participants
Lifespan.io (LEAF) - 09-Oct-2024The findings open new avenues for therapies aimed at slowing the ageing process
"Weight-adjusted waist index" is better than BMI at measuring obesity
Live Forever Club - 15-Jul-2024Higher WWI correlates with shorter telomeres, suggesting increased health risks
New drug regenerates brainpower and muscle strength in mice
Lifespan.io (LEAF) - 24-Jun-2024Small molecule unlocks youthful telomerase, reversing age-related decline in mice
Telo-seq precisely measures telomere length and sequence on individual chromosomes
Medical Xpress - 19-Jun-2024It can also help personalise treatments for telomere-related diseases
Calorie restriction initially speeds up, then slows down, biological ageing
Live Forever Club - 20-May-2024Clearly, eating less may not be a straightforward path to slowing ageing
/calorie-restriction-cr-thumbnail.jpg "Click to read article")
Study reveals surprising telomere loss patterns in calorie restricted humans
Pennsylvania State University (PSU) - 17-Apr-2024Complexities spark hope for health benefits beyond telomere length
Telomeres are different lengths than scientists previously thought
Phys.org - 11-Apr-2024This could transform how we approach diseases linked to cell ageing
Telomere-based interventions offer promising avenues for combating ageing
Live Forever Club - 23-Feb-2024Telomere research is in its early stages, with much to be discovered
Telomir Pharmaceuticals IPO raises $7 million to combat ageing
Telomir Pharmaceuticals - 13-Feb-2024Aims to develop telomere-based therapies for age-related inflammatory diseases
Green neighborhoods linked to longer lives and slower ageing
The Guardian - 01-Dec-2023Every 5% increase in green space adds 1% younger cells to your body
New mice with human-like telomeres could help us fight ageing and cancer
The Jerusalem Post - 30-Oct-2023Model could be used to study the role of telomere length in several diseases
Regular jogging or running could help to keep cells younger and healthier
Live Forever Club - 26-Oct-2023Jogging or running for at least 75 minutes per week linked to longer telomeres
Rejuvenation Technologies raises $10.6M to develop anti-ageing therapies
Longevity Technology - 07-Sep-2023A single dose of mRNA therapy could rewind ageing and extend lifespan
Telos Biotech parent, Cambrian Bio, to develop robust cell therapies for treating age-related diseases
Longevity Technology - 27-Jun-2023Novel recombinant protein to manufacture biologically fit cells by safely lengthening telomeres
Summary of Fabrizio d’Adda di Fagagna presentation at Longevity Med Summit
Live Forever Club - 18-May-2023Telomeres become sinks of irreparable damage - antisense oligonucleotides could potentially provide a fix
Telomere length may have protective effects against dementia-provide a pathway for future research
Oxford Population Health - 22-Mar-2023Associations between telomere length and endophenotypes could help treat neurodegenerative disease
Telomeres encode two novel signaling proteins may change our understanding of cancer and aging
Phys.org - 20-Feb-2023Blood tests for proteins encoded by telomeres could give information of biological age and cancer
Telocyte secures new investment, taking telomerase gene therapy to the clinic in CVD and more
Longevity Technology - 03-Feb-2023The researchers will not only focus on CVD or cellular aging but the optimal point of intervention
Researchers found a missing genetic link that helps melanoma cells defeat mortality
EurekAlert! - 10-Nov-2022Mutations in a telomere binding protein provide a new approach to treat melanoma and other cancers
Excessive alcohol consumption may age you faster by accelerating your biological age
Interesting Engineering - 28-Jul-2022Alcohol consumption causes telomere shortening, leading to several age-related diseases
New insight on the accumulation of senescent cells in humans
UPMC - 30-Jun-2022Oxidative DNA damage induce rapid senescence compared with shorter telomeres from repeated cell divisions
Lifespan of middle-aged mice increased by a third with telomerase gene therapy
CISION PR Newswire - 19-May-2022Treatment used proprietary CMV vector which is able to deliver multiple genes into the nucleus
Viral-vector gene therapies could unlock healthy life extension in humans
Lifespan.io (LEAF) - 12-May-2022Lifespan of mice greatly extended even when treatment only started at the equivalent of 56 years old
Faster walking associated with longer telomeres, could improve health and lifespan
Lifespan.io (LEAF) - 11-May-2022We know exercise keeps people healthier and this may be just one of the underlying mechanisms
New study where biological age reduces as chronological age increases
Bioviva Science - 18-Nov-2021Evident reversal of Dementia symptoms sustained cognitive improvement
A new model enter into telomere-mediated senescence to reduce genome damage
Genetic Engineering & Biotechnology News (GEN) - 10-Nov-2021Telomeres repair can prevent senescence and genome instability
Biobank study: People with longer telomeres live 2.5 years longer
Lifespan.io (LEAF) - 13-Oct-2021New insights into the genetic regulation of leukocyte telomere length
Activation of telomerase gene prevents aging in certain types of cells
EurekAlert! - 23-Jul-2021DNA region: VNTR2-1 plays a role in human aging and tumorigenesis
Bigmouth buffalo fish can live up to 112 years with no signs of ageing
Lifespan.io (LEAF) - 06-May-2021Long-living fish gives key insights on evolution history to age slower and live longer
BioViva tests experimental telomerase gene-therapy in 6 Alzheimer's patients
Biospace - 03-May-2021Launched home test to track biological age; outcomes of unlicensed gene-therapy are yet to report
Atomic structure of human telomerase developed using cryo-electron microscopy
Phys.org - 22-Apr-2021High resolution telomerase model revealed new protein subunits; promises new therapy for aging diseases
Body's own drug, spermidine prevents age-related pathologies
Innovation Origins - 23-Feb-2021Spermidine supplemented mice showed anti-ageing effects by preserving telomere length
Fraility maybe a better marker for ageing than telomere length
Longevity Technology - 07-Jan-2021Telomere length may not be an accurate indicator of lifespan & health in the elderly
Stem cells protect chromosomal ends differently than normal cells
The University of Sydney - 26-Dec-2020Insights on this unique strategy could have breakthrough treatments for ageing and many diseases
Telomere shortening - a new milestone in cancer therapy
Medical News Today - 25-Dec-2020Shortening telomere length in cancerous cells will prevent them from dividing
A mushroom compound that could prevent telomere shortening
NutraIngredients-USA - 14-Dec-2020Antioxidant ergothioneine alleviates harmful effects of oxidative stress on telomere length
Study supports link between ageing, telomere length & cancer
New Atlas - 02-Dec-2020Telomere shortening might be a protective measure to ward off cancers as we age
Oxygen therapy reversed the human age biologically
YAHOO! - 18-Nov-2020Not as easy as taking a pill, but a stunning result on both telomeres and senescent cells
NAD precursor could prevent telomere loss
Longevity Technology - 04-Nov-2020Restoring NAD homeostasis could help in ageing diseases with telomere dysfunction
Mechanism underlying telomere restoration in T cells discovered
Lifespan.io (LEAF) - 20-Oct-2020Telomere transfer from APCs boosts T cells lifespan-helpful in immunosenescence
New discovery explains mechanism regulating telomere length and function
Phys.org - 13-Oct-2020Now we can better understand processes that regulate cell survival in ageing
New technique to measure individual telomere lengths in 3 hours
Phys.org - 25-Sep-2020Not just average length that is important, so full profile provides more clinical uses
Eating junk food could make you age faster
ScienceAlert - 01-Sep-2020Study finds link between ultra processed food and shorter telomeres
Telomerase gene therapy prevents age-related lung fibrosis in mice
Pulmonary Fibrosis News - 19-Aug-2020Could pave way for preventing the disease in humans and improve healthspan
A step closer to reversing pulmonary fibrosis via telomerase gene therapy
Lifespan.io (LEAF) - 12-Aug-2020Study in mice revealed great progress and potential for curing fibrotic diseases in humans
Mindfulness meditation prevents shortening of telomeres
Psych Central - 27-Jul-2020Only a small study (17 meditators) but interesting nonetheless
Telomerase activity restored in vitro and in mice
Lifespan.io (LEAF) - 27-Apr-2020Potential to support new therapies for dyskeratosis congenita, other age-related diseases
Discovery of molecules allowing telomere restoration
New Atlas - 26-Apr-2020Demonstrated in mice, study paves way for treating ageing-related diseases
Rapamycin decreased survival and longevity in mice with short telomeres
Phys.org - 03-Mar-2020mTOR, a pro-survival pathway for shorter telomeres and inhibition is deleterious
Human trials to test efficacy and safety of genetic introduction of telomerase
Genome Context - 23-Nov-2019Telomeres: are we about to crack the secrets of anti-ageing
Dr. Michael Fossel interviewed by LEAF
Lifespan.io (LEAF) - 18-Nov-2019Fossel argues for telomerase therapy over senolytics
Mice with extra-long telomeres lived longer
ScienceAlert - 21-Oct-2019Will we be able to have a longer lifespan by lengthening our telomeres too?
Don't hurry to predict your longevity with biomarkers
The Scientist - 27-Sep-2019Longevity results can be unproven and not ready in some aspects for being used in clinics
Telomere length linked to the nervous system
Medical Xpress - 26-Sep-2019According to the study, shortening in the telomere length have reflected in our brain structure
Michael West examines how to safely revive telomerase
Lifespan.io (LEAF) - 12-Sep-2019It powers foetal development and telomere length, but also cancers
Leukocyte telomere length found to be linked to DNA methylation (DNAm)
News Medical - 02-Sep-2019Yet more evidence that hallmarks of ageing are inter-related, not standalone actions
Pluripotency and telomeres, butterfly effect discovered
ScienceDaily - 20-Aug-2019Pluripotent cells are like a black box, but they can open new doors for regenerative medicine
Longer telomeres linked to reduced risk of psychiatric problems in men
Oxford University Press - 05-Jun-2019But telomere length is not linked to overall multimorbidity
Telomerase therapy for neurodegeneration
Lifespan.io (LEAF) - 04-Jun-2019Telomerase gene therapy may be a potential solution for age-related neurodegenerative diseases
Direct oxidative stress on telomeres leads to faster cellular ageing
News Medical - 14-May-2019Prevents uncontrolled cell division in cancer cells
Environmental pollutants in household items can affect ageing
INVERSE - 02-May-2019Reduces length of telomeres and alters mitochondrial DNA levels in cells
New telomeres lengthening treatment - space flight!
Independent - 11-Apr-2019Unfortunately the effect disappears after returning to Earth
Exercise lengthens telomeres (slows aging)
NHS - 29-Nov-2018Endurance and interval training groups saw telomeres increase by over 3%.
2018 Telomere Length Update by Liz Parrish
Bioviva Science - 24-Sep-2018A case of muscular and cellular rejuvenation thanks to myostatin and telomerase therapies
Telomerase Gene Therapy Does Not Increase Cancer Risk
Lifespan.io (LEAF) - 27-Aug-2018New research proves telomerase therapy's safety by making its effects within the cell temporary
Telomere loop structure more important than length
Medical Xpress - 20-Jul-2018Telomere structure rather than length may be the key to prevent aging
Telomerase: Downgraded by long term proponent
Josh Mitteldorf Blog - 19-Mar-2018Josh Mitteldorf curbs his enthusiasm based on latest study.
Motherhood Causes 11 Years of Telomere Shortening
ScienceAlert - 26-Feb-2018DNA collected from nearly 2,000 reproductive-age women.
Long-Lived Bats Have Telomeres That Don't Shorten
INVERSE - 07-Feb-2018These mouse-sized mammals live way longer than they should.
Telomeres Do Not Translate Into A Younger Biologic Age
Institute For Aging Research - 31-Jan-2018TERT is a subunit of the enzyme telomerase.
Prenatal pollution exposure linked to decreased telomere length
2 Minute Medicine - 25-Oct-2017Telomeres are short stretches of DNA are the ends of chromosomes and are essential for fidelity of genetic information during cell division.
Direct correlation between telomere length and heart failure found
Medical Xpress - 07-Sep-2017Study used human heart tissue samples from organ donors and heart transplants patients.
Josh Mitteldorf argues against long telomeres causing cancer
Josh Mitteldorf Blog - 23-Aug-2017Major new study argues that longer telomeres increase risk of cancer five-fold.
Research holds Promise for Future Clinical Therapies to Slow Aging
Next Big Future - 01-Aug-2017Cells from children with progeria studied.
Scientists Discover Master Regulator of Cellular Aging
Scripps Research Institute - 12-Jan-2017Newly discovered a protein, named TZAP, binds the ends of chromosomes.
Poor Correlation Between Telomere Length and Health
Fight Aging! - 02-Sep-2016Telomeric DNA decreases with age and when they get too short cells self-destruct or become senescent.
Telomere Length Does Not Predict Atherosclerosis Risk
Fight Aging! - 25-May-2016Epidemiological studies have demonstrated shorter leukocyte telomere length (LTL) in patients suffering coronary artery disease, heart attack or stroke.
Impatient People Likely To Age Faster
Tech Times - 24-Feb-2016Shorter telomeres discovered in impatient subjects.
How Long Will You Live?
Veritasium - 25-Nov-2015Great video introduction to one of the causes of aging – telemere length v cancer inducing telemerase.
Telomeres naturally shorten each time DNA is copied in preparation for cell division
Kurzweil Network - 13-Nov-2015Shortened telomeres have been implicated in aging and disease.
Alpha lipoic acid lengthens telomeres
Emory University - 20-Aug-2015Dietary supplement alpha lipoic acid (ALA) can stimulate telomerase, the enzyme that lengthens telomeres, which could have positive effects on chronic diseases such as atherosclerosis and diabetes. ALA is present in many foods and counteracts high-fat-die
Telomere Length and Mortality
Humanity+ - 04-May-2015Danish study of 65,000 people shows telomere length robustly predicts longevity.
Telomere extension turns back aging clock in cultured human cells
Stanford University - 22-Jan-2015Researchers delivered a modified RNA that encodes a telomere-extending protein to cultured human cells. Cell proliferation capacity was dramatically increased, yielding large numbers of cells for study.
Telomerase “off” switch discovered; stops cells dividing indefinitely
Salk Institute - 19-Sep-2014The study was published in the Genes and Development journal.
