Optispan Podcast
Longevity podcast with Matt Kaeberlein
The Optispan Podcast with Matt Kaeberlein aims to bring insights from the geroscience and longevity world into the public to help people optimize their healthspan and improve their quality of life.
We believe that everyone can get closer to their own optimal healthspan. We hope you find this content valuable, subscribe to the channel, and come back often. More importantly, we hope that you apply what you learn here to recover your lost decade, and perhaps much more.
Visit website: https://www.youtube.com/@optispan
See also: 
Optispan
- Promoting healthspan and longevity
Details last updated 06-Aug-2024
Mentioned in this Resource
Optispan Podcast Creations
Dr Seager: Rethinking Health for Longevity
Matt interviews Thomas Seager to explore the challenges and future prospects of healthcare
Death, Grief, & Purpose from a Longevity Science Perspective
Matt and Nick share their recent personal experiences with navigating grief and loss
Nutrition Myths, Gut Fixes, Natural Health Tips from a Doctor of Naturopathy
Matt interviews naturopathic doctor Kim Celmer on the unique approach NDs bring to patient care
We are Keeping People Sick Longer - We Need Medicine 4.0
Matt traces the path from Medicine 1.0 to 3.0, envisioning a future with Medicine 4.0
The Probability of Us Living to Be Much Older?
Matt and Nick explore the recent Nature Aging paper on life extension
Longevity Scientist Answers Burning Questions About Health Trends
Nick engages Matt with a wide range of questions
Brain Repair: The Ketamine Combo Treatment for Depression and Chronic Pain
Matt and Jon Berner explored the potential of rapamycin and ketamine
GLP-1 Agonists Could Delay Aging? A Scientist Weighs In
Matt and Nick discuss how GLP-1 agonists might slow biological ageing
Anti-Aging Enthusiasts are Taking this Pill to Extend Their Lives?
Matt and Nick discuss a recent New York Times article on rapamycin
Brain Disorder Expert: Tackling Alzheimer’s & Other Brain Disorders with LITHIUM
Matt and Jon Berner discuss the potential therapeutic uses of lithium
Don’t Drink Your Coffee First Thing in the Morning?
Matt and Nick discuss the best time to have caffeine in the morning
Metformin Decelerates Aging Clocks & Slows Brain Aging? We Take a Look.
Matt and Nick discuss a paper showing that metformin slows biological ageing in male primates
Does Plant Protein Slow Your Aging?
Matt explored the link between consumption of plant and animal proteins
The Dog Aging Project that aims at Helping Dogs Live Longer
Matt explores the Dog Aging Project's complex 10-year journey
You Should Focus on THESE 4 Things for Your Health & Longevity
Matt introduces the Optispan series on the "Pillars of Healthspan"
NEW PEARL Trial Results: Your Questions Answered on Aging with Rapamycin for Longevity
Matt addresses unanswered questions from the PEARL trial webinar
Q&A with Scientist Matt Kaeberlein about Longevity and Living Longer
Matt Kaeberlein addresses questions on promoting healthy ageing
Flaws in the Healthcare System, Preventative Medicine, and Next-Gen Healthcare (Part 3)
Matt and Kevin White discuss about the future of personalized healthcare
Flaws in the Healthcare System, Preventative Medicine, and Next-Gen Healthcare (Part 2)
Matt and Kevin White discuss about bloodwork results
Flaws in the Healthcare System, Preventative Medicine, and Next-Gen Healthcare
Matt and Kevin White discuss transitioning from research to entrepreneurship
Longevity Expert Sheds Light on common MISCONCEPTIONS for People’s’ Health
Matt addresses common misconceptions about longevity and healthspan
Longevity Expert Matt Kaeberlein Exposes Common Myths Circulating the Media
Matt Kaeberlein examines widely held beliefs about longevity
Dentist Reveals Exciting Research Findings Involving Rapamycin on Oral Health
Jonathan An unveils ground-breaking rapamycin research on oral health
Rapamycin’s Impact on Oral Health & its Relationship to Ageing (Part 2)
Matt and Jonathan An explore the connection between oral health and ageing
Rapamycin’s Impact on Oral Health & its Relationship to Aging
Matt and Jonathan An explore the connection between oral health and ageing
Mike Mutzel on Choosing YOUR Supplements, Cholesterol & Social Health
Matt discusses a variety of healthspan topics with Mike Mutzel
This Study Says IL-11 Inhibitor Drug May Extend Lifespan
Matt explains the function of IL-11 in the body
Off-Label Rapamycin Experiences & Doses
Matt shares his personal experience with using rapamycin off-label
Rapamycin’s possible SIDE EFFECTS & BENEFITS
Matt discusses about the potential benefits and side effects of using rapamycin off-label
What a 93-Year-Old Rowing Champion Can Teach Us About Aging Well
Matt discusses a 93-year-old rowing champion's lifestyle and the concept of "sickspan"
Transforming Our Understanding of Healthcare Through Geroscience
Matt explores how geroscience shapes ageing
Uncovering New Longevity Research DISCOVERIES: The Power of 3HAA Revealed
Matt talks with George Sutphin about his research on the genetic influences of ageing
Matt Kaeberlein’s ALLERGIC REACTION to Medication While on Rapamycin
Matt shares his recent experience of developing a bacterial infection while on antibiotics
Longevity Science 2024: New Insights on "The Hallmarks of Aging" & What They Mean
Matt reviews the hallmarks of ageing, their limits, and impact on geroscience
Current Healthcare ISN’T CUTTING IT: How Optispan is REVOLUTIONIZING it
Matt explains his decision to leave academia to contribute to a healthcare revolution
CAR T Cells: The Ultimate Anti-Aging Solution?
Matt reviews a new paper on the impact of senolytic CAR T cell therapy on ageing in mice
People are GETTING THIS WRONG about Supplements & My Supplement List
Matt talks about his fairly cautious approach to using supplements
Rapamycin’s SURPRISING Effects on Aged IMMUNE SYSTEMS
Matt discusses research showing that rapamycin revitalizes the ageing immune system in mice
Does this Dog Supplement Really Work to REVERSE AGE? (PART 1)
Matt critically examines the claims purported to reverse age-related decline in dogs
Does this Dog Supplement Really Work to REVERSE AGE? (PART 2)
Matt analyses a clinical trial on the supplement "Leap Years"
Answering Your Questions on Rapamycin: Optimal doses, tests, & stacks
Matt responds to audience questions on rapamycin
The Importance of Body Composition & Ways YOU can measure it
Matt exploring DEXA scans for health optimization
“Zombie” Senescent cells may play HUGE role in LIVING LONGER, Here’s How
Matt talks with Natalia Mitin about assessing cellular senescence
These 14 Medications are linked to lower death rates in humans
Matt reviews the study's most effective drugs for extending lifespan
Doctors overlook how significantly this impacts your health
Matt discusses easy-to-implement preventative measures in medicine
How "light-sensitive" proteins are being used to fuel scientific discovery
Brandon Berry and Matt discuss the development and application of optogenetic tools
Are DEXA scans ACCURATE? What YOU NEED to KNOW
Matt reviews DEXA scan results for personalized health optimization
Inside this Non-profit’s AMAZING Strategy to Fight Aging
Matt discusses the creation of a bipartisan longevity science caucus with Dylan Livingston
Aging Expert Explains How Healthcare got it ALL WRONG
Matt discusses the journey to modern medicine, contrasts 19th and 21st century approaches
AI vs Aging: Why Wormbot-AI is the secret weapon against disease
Matt and Mitchell Lee discuss the current state of drug discovery in the longevity field
Reversing Biological Age: Have we finally found the answer?
Matt explored the effects of E5, a pig blood-derived compound
Comparing Bryan Johnson’s RAPAMYCIN DATA: INTERESTING RESULTS
Matt discusses his experiences with off-label use of rapamycin from a recent course
The Best Strategies for Living Longer RANKED: Longevity Tier List
Matt and Nick explore popular strategies for optimizing healthspan
WELLNESS REVOLUTION: Taking Accountability to Achieve a Health Transformation
Stuart McKee discusses his personal health journey
DON’T Take Resveratrol Until You Watch This Video
Matt provides an in-depth review of the current research on resveratrol
The Surprising Way Body Size Relates to Lifespan
Matt explores the intricate relationship between body size and the rate of ageing
Is This The Best Time to Exercise?
Matt and Nick explore three recent findings in geroscience and healthspan
Your Dog Needs Your Help
Matt discuss about the Dog Aging Project to study ageing in dogs and humans
Supplement Industry Secrets: What They Aren’t Telling You About NAD+ & NMN
Matt and George discuss new findings that NAD+ supplements may signal kidney damage
The Two New Highest Ranked Compounds For Lifespan Extension According to the ITP
Matt discuss about the two top-ranked compounds for lifespan extension
IL-11, Trametinib & Rapamycin = Impressive Lifespan Effects? We Take a Look
Matt covers two mouse lifespan studies on IL-11 inhibition and trametinib-rapamycin treatment
Matt Kaeberlein reflects on "David Sinclair’s Longevity Lie"
Matt and Nick offers their perspective on "David Sinclair’s Longevity Lie"
Does NMN Actually Increase VO2 MAX?
Matt and Nick examined a 2022 study that looked at effects of NMN supplementation on VO2 max
The UNEXPECTED Ozempic Weight Loss Body Scan Results (DEXA)
George Sutphin shares his DEXA scan and VO2 max results
Solving the "Lack" of Anti-aging Discovery & Ranking Current Interventions
Matt and Mark discuss aminoacyl-tRNA synthetases, enzymes crucial for protein synthesis
How Pregnancy Affects Aging, New Model Organisms for Aging Research, HRT
Matt and Berenice talk ovaries, menopause, hormone therapy, and her journey to a dream lab
Why Drinking a Banana Smoothie IS the Same as Eating a Banana
Matt examines a 2023 article to see if bananas in smoothies are a concern
Scientists Discuss Longevity Interventions & Optimisms
Matt and his former lab members discuss and debate longevity
Trying Cold Plunge & Sauna w/ Mike Mutzel (Risks & Benefits Discussion)
Matt and Nick share their personal experiences with cold plunge and sauna
Debating Claims About NR & Rapamycin
Matt and Nick dive into the recent debates and responding to expert feedback on rapamycin and alpha-ketoglutarate
Answering Questions on RAPAMYCIN (Gold Standard Longevity Intervention)
Matt addresses audience questions on rapamycin's anti-ageing potential, dosing, and research
Responding to Comments that Disagree with Us on Longevity
Matt and Nick address viewer feedback to correct and clarify longevity science topics
Stem Cells, Aging Hallmarks & Rapamycin
Matt and longevity expert Kevin White discuss advancements in geroscience and age management
Scientists Debate How to Live Longer & Longevity Drugs
Matt and Charles discussed geroscience, sirtuins, and NAD+ boosters
Scientist Reacts to Greg Doucette’s Controversial Take on DEXA Scans
Matt and Nick react to Greg Doucette's critique of DEXA scans
Most Longevity Experts Don’t Tell You This About Aging
Matt explores ways to identify and classify ageing genes to predict age and enhance longevity
Longevity Scientist Critiques Mike Israetel’s "Exercise Scientist Critiques"
Matt and Nick react to Mike Israetel's views on anti-ageing strategies
The Benefits of Protein Restriction, How Protein Affects Hormones & FGF21
Matt and Cristal discuss fibroblast growth factor 21 (FGF21) and its influence on ageing
A Company’s New Longevity Senolytic Drug & The Drug Development Process
Matt and David provide an inside glimpse into the drug development process
Longevity Scientist Reacts to Bryan Johnson’s "I Edited My DNA To Live Forever"
Matt reacts to Bryan Johnson's Minicircle gene therapy video and answers Nick's questions
DNA Damage, Senescence & Apoptosis
Matt and Aditi discuss about senescent cells and its relevance to ageing
A Longevity Breakthrough w/ Yamanaka Factor "Rejuvenation Cocktail?"
Matt and Nick react to Aspen Ideas Festival panel discussion
