This episode of Optispan features Matt Kaeberlein and Kevin White as they explore the benefits, risks, and misconceptions surrounding testosterone replacement therapy (TRT). The discussion covers symptoms of low testosterone, the appropriate timing for testing, and the distinctions between primary and secondary hypogonadism.

Key Points:

This episode explores the benefits, risks, and misconceptions of testosterone replacement therapy (TRT) for men. Experts Matt Kaeberlein and Dr. Kevin White discuss how testosterone levels decline with age and various treatment options, providing insights into optimizing hormone health for longevity and well-being.

• The Gradual Decline of Testosterone in Men: Testosterone levels naturally decrease with age, often leading to symptoms like fatigue, stress intolerance, and reduced muscle mass. Many men delay seeking treatment until symptoms significantly impact their quality of life.
• Symptoms & When to Get Tested: Signs of low testosterone include fatigue, poor sleep, low libido, muscle loss, and stress intolerance. Experts recommend getting tested around age 40 as part of general health monitoring.
• Primary vs. Secondary Hypogonadism: Low testosterone can result from testicular dysfunction (primary hypogonadism) or inadequate signals from the brain (secondary hypogonadism). Identifying the root cause helps determine the best treatment approach.
• Different Treatment Options: Injections, Creams, and More: TRT options include injections, topical gels, oral medications, and implanted pellets. Injections (twice weekly) are often preferred for maintaining stable hormone levels.
• Addressing Risks: Cancer, Mood, and Heart Health: Properly managed TRT does not increase cancer risk and may reduce cardiovascular disease risk. Side effects like hair loss, fertility loss, and mood swings are manageable with the right approach.
• Can Testosterone Therapy Improve Longevity?: Evidence suggests TRT may enhance longevity by improving muscle mass, bone density, metabolic health, and overall well-being. Experts emphasize individualized treatment to avoid unnecessary risks.