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Proceedings of the National Academy of Sciences (PNAS)

Multidisciplinary scientific journal, official journal of the National Academy of Sciences

The Proceedings of the National Academy of Sciences (PNAS), the official journal of the National Academy of Sciences (NAS), is an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences. The journal is global in scope and submission is open to all researchers worldwide.

PNAS was established in 1914 in honor of the semicentennial anniversary of the National Academy of Sciences. Since then, we have worked to publish only the highest quality scientific research and to make that research accessible to a broad audience. In addition, PNAS publishes science news, Commentaries, Perspectives, Colloquium Papers, podcasts, and profiles of NAS members.

In 1995, PNAS began accepting Direct Submissions from researchers without an NAS affiliation. While we retain strong ties with the NAS, whose members oversee the journal’s rigorous three-tier peer review process, we now receive more than 17,000 Direct Submissions each year. Direct Submissions account for more than 75% of the research we publish.

Visit website: https://www.pnas.org/

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Details last updated 04-Feb-2019

People at Proceedings of the National Academy of Sciences (PNAS)

Carolyn Beans

Freelance science reporter

Proceedings of the National Academy of Sciences (PNAS) News

Brain removes toxins through special channels while you sleep

Brain removes toxins through special channels while you sleep

Medical News Today - 14-Oct-2024

This process occurs mainly at night and may help prevent Alzheimer’s

Space travel rapidly ages the human heart, study finds

Space travel rapidly ages the human heart, study finds

Nature - 24-Sep-2024

Just one month in microgravity weakens heart tissue and triggers molecular changes

Bolivian tribe has the healthiest hearts and slowest-ageing brains ever studied

Bolivian tribe has the healthiest hearts and slowest-ageing brains ever studied

BBC - 17-Aug-2024

However, modern changes like processed foods are starting to affect their health

New drug prototype offers hope for repairing damaged lungs

New drug prototype offers hope for repairing damaged lungs

EurekAlert! - 10-Apr-2024

The drug targets the lungs and activates stem cells

Facial, tongue, and retinal images can now reveal your biological age

Facial, tongue, and retinal images can now reveal your biological age

Live Forever Club - 11-Jan-2024

AgeDiff could be a new way to predict disease risk and personalise healthcare

A cellular protein called HKDC1 tidies up mitochondria and lysosomes

A cellular protein called HKDC1 tidies up mitochondria and lysosomes

Interesting Engineering - 01-Jan-2024

This discovery paves the way for potential anti-ageing therapies

Scientists find a new way to replace lost neurons after stroke

Scientists find a new way to replace lost neurons after stroke

Kyushu University - 17-Oct-2023

Microglia conversion sparks a paradigm shift in stroke treatment

Dementia rate declined in the US, but inequalities still persist in gender and racial groups

Dementia rate declined in the US, but inequalities still persist in gender and racial groups

RAND - 07-Nov-2022

Education could be a vital tool to narrow down the differences in risk of dementia

Researchers claim to have uncovered secret to immortality in jellyfish

Researchers claim to have uncovered secret to immortality in jellyfish

Futurism - 01-Sep-2022

what this means to humans? - a possibility to treat overwhelming aging disorders

Lifespan of middle-aged mice increased by a third with telomerase gene therapy

Lifespan of middle-aged mice increased by a third with telomerase gene therapy

CISION PR Newswire - 19-May-2022

Treatment used proprietary CMV vector which is able to deliver multiple genes into the nucleus

Viral-vector gene therapies could unlock healthy life extension in humans

Viral-vector gene therapies could unlock healthy life extension in humans

Lifespan.io (LEAF) - 12-May-2022

Lifespan of mice greatly extended even when treatment only started at the equivalent of 56 years old

Sleeping with lights on may alert your body, harming good night's rest and overall health

Sleeping with lights on may alert your body, harming good night's rest and overall health

Northwestern University - 14-Mar-2022

Even moderate light exposure while sleeping increases heart rate and glucose levels

Activation of telomerase gene prevents aging in certain types of cells

Activation of telomerase gene prevents aging in certain types of cells

EurekAlert! - 23-Jul-2021

DNA region: VNTR2-1 plays a role in human aging and tumorigenesis

Toxic lead levels still exists in the London air, even after 20 years of fuel ban

Toxic lead levels still exists in the London air, even after 20 years of fuel ban

Guardian - 21-Jun-2021

Land contamination can be tackled by placing clean soil on top, but is that enough?

Stem cell therapy: A potential avenue for reversing pituitary gland ageing

Stem cell therapy: A potential avenue for reversing pituitary gland ageing

Medical Xpress - 15-Jun-2021

Slowing down natural ageing process of pituitary glands with stem cells

Carbon nanotubes deliver drugs directly to targeted site

Carbon nanotubes deliver drugs directly to targeted site

Nano Magazine - 05-May-2021

Breakthrough strategy involving fusion of drug carrier membrane with the cell

CRISPR cuts cholesterol by 57% with just one shot

CRISPR cuts cholesterol by 57% with just one shot

Phys.org - 01-Mar-2021

Tiny lipid particles with gene editing machinery selectively targets liver and reduces cholesterol in mice

One time injection of nanoparticles to treat skin cancer

One time injection of nanoparticles to treat skin cancer

Yale News - 02-Feb-2021

Nanoparticles with chemotherapy agent act longer, a potential alternative to cancer surgeries

New approach to bring 3D functional organs to reality

New approach to bring 3D functional organs to reality

University of Washington - 18-Jan-2021

Hydrogels in tissue engineering with cell signaling protein combinations

Genetically engineered T cells destroy pathogenic T cells in mice

Genetically engineered T cells destroy pathogenic T cells in mice

Medical Xpress - 03-Dec-2020

Directing T cells to attack other T cells - a new treatment for autoimmune diseases?

A new enzyme discovered to reverse cellular ageing

A new enzyme discovered to reverse cellular ageing

Phys.org - 30-Nov-2020

Molecular simulations have discovered an enzyme with anti ageing and anti tumour effects

Drug guided stem cell migration improves healing in mice

Drug guided stem cell migration improves healing in mice

Science Daily - 24-Nov-2020

First ever drug guided stem cell therapy in the field of regenerative medicine

Be more generous to live longer and happier

Be more generous to live longer and happier

Guardian - 24-Nov-2020

Study finds higher survival in societies that provide more support & care

Time to hit the right balance in your diet

Time to hit the right balance in your diet

INVERSE - 17-Nov-2020

A good balance of various macronutrients can help you live longer

Early detection of osteoarthritis using machine learning

Early detection of osteoarthritis using machine learning

National Institutes of Health (NIH) - 07-Oct-2020

Cartilage maps along with machine learning algorithms predict arthritic cases

Treating space induced muscle and bone loss in mice

Treating space induced muscle and bone loss in mice

Astronomy - 09-Sep-2020

We can probably take space holidays without worrying about muscle wasting in future

This therapy attacks solid-tumor cancer cells in mice, humans

This therapy attacks solid-tumor cancer cells in mice, humans

EurekAlert! - 29-Jun-2020

CAR-T therapy, a proven approach, now improved to broaden potential targets

Stem cell transplantation repairs stroke-injured rat brains

Stem cell transplantation repairs stroke-injured rat brains

Medical Xpress - 08-Apr-2020

New possibility on restoring injured neural circuitry in humans after stroke

Mobility and sense of touch restored in stroke-injured rat brains

Mobility and sense of touch restored in stroke-injured rat brains

Lund University (Lunds Universitet) - 08-Apr-2020

Stem cell transplantation gives hope to humans affected by stroke

Female of the species always outlives the males

Female of the species always outlives the males

BBC - 24-Mar-2020

Humans more equal than most species because less of an environmental effect

Pre-mature deaths in adults may be prevented, shown by HLI's largest study

Pre-mature deaths in adults may be prevented, shown by HLI's largest study

EurekAlert! - 27-Jan-2020

Made possible by early detection of disease and disease risks through whole genome sequencing

Clinicians identified adults at risk for key health conditions

Clinicians identified adults at risk for key health conditions

Business Wire - 27-Jan-2020

Studies were done by integrating whole-genome sequencing with advanced imaging and blood metabolites

Could immune cells be the secret to extreme longevity?

Could immune cells be the secret to extreme longevity?

Live Science - 15-Nov-2019

Unusually high concentrations of T helper cells found in supercentenarians bloodstream

High levels of killer cells in the immune system of supercentenarians

High levels of killer cells in the immune system of supercentenarians

Medical Xpress - 13-Nov-2019

Relatively immune to infections and cancers - also get to live more than 110 years

Protein misfolding ruins the young and beautiful cell

Protein misfolding ruins the young and beautiful cell

Phys.org - 17-Oct-2019

Presence of free radical damage significantly reduced the lifespan in worm model

Zapping the brain to cure morbid obesity

Zapping the brain to cure morbid obesity

Metro - 19-Aug-2019

May be the last option to save morbidly obese - already successful in mice

A genetic mutation that happened 3 million years ago causes heart attacks

A genetic mutation that happened 3 million years ago causes heart attacks

Guardian - 22-Jul-2019

It may reduce atherosclerosis, but what about other chronic diseases?

Young mouse blood can reverse declines in the brains of older mice

Young mouse blood can reverse declines in the brains of older mice

earth.com - 04-Jun-2019

Two proteins may be responsible for improving brain cell growth

Placental stem cells can regenerate damaged heart cells

Placental stem cells can regenerate damaged heart cells

New Atlas - 22-May-2019

Creating beating cells and blood vessels that could treat heart attack victims

Graphene scaffolds have the potential to repair bones faster

Graphene scaffolds have the potential to repair bones faster

Singularity Hub - 04-Mar-2019

Already shown success in mice- could become a vital part of orthopaedic medicine

Biological age of women's brains 3 year younger than men's

Biological age of women's brains 3 year younger than men's

Independent - 04-Feb-2019

As more people suffer from dementia, men will be affected sooner

65% worldwide increase in antibiotic use

65% worldwide increase in antibiotic use

Guardian - 26-Mar-2018

65% rise in worldwide consumption of the drugs from 2000 to 2015. Public health experts call for...

How to avoid catching a virus on a plane

How to avoid catching a virus on a plane

Science Magazine - 19-Mar-2018

Study provides blueprint for how a virus could move around a plane. Human movement spreads more ...

What is 'Aussie' flu and should we be worried?

What is 'Aussie' flu and should we be worried?

BBC - 08-Jan-2018

Aussie flu or H3N2 is an influenza A virus that appears to cause more severe infections in young ...

Physicists take first step toward cell-sized robots

Physicists take first step toward cell-sized robots

Cornel Chronicle - 02-Jan-2018

Robot exoskeleton can rapidly change shape upon sensing chemical or thermal changes. The machine...

Scientists decipher mechanisms underlying the biology of aging

Scientists decipher mechanisms underlying the biology of aging

Phys.org - 02-Nov-2017

Used a combination of engineering, computer science and biology to analyze molecular processes. ...

Indoles In Bowel Responsible For Longer Healthier Lives

Indoles In Bowel Responsible For Longer Healthier Lives

Medical Research - 22-Aug-2017

Study into role of microbiota (bacteria inside and on body) on health span of animals.   Widely ...

Ultra-tough antibiotic to fight superbugs

Ultra-tough antibiotic to fight superbugs

BBC - 30-May-2017

US scientists have re-engineered the antibiotic vancomycin. Appears to be a thousand times more ...

Induced pluripotent stem cells don’t increase genetic mutations

Induced pluripotent stem cells don’t increase genetic mutations

ScienceDaily - 07-Feb-2017

iPSCs treatments have been slowed by concerns that these cells are prone to increased numbers of ...

First stable semisynthetic organism created

First stable semisynthetic organism created

Kurzweil Network - 03-Feb-2017

Bacterium with two new synthetic bases (called X and Y) added to the four natural bases (A, T, C,...

Personalised medicine boost as cancer drug monitored in real-time

Personalised medicine boost as cancer drug monitored in real-time

Chemistry World - 13-Jan-2017

Aptamer-based sensors can track levels of small molecules in mobile rats. Could continuously gui...

Cognitive speed training exercises reduce dementia

Cognitive speed training exercises reduce dementia

iMedicalApps - 01-Aug-2016

Brain training industry careful about claims after Lumosity was fined $50 million dollars for lac...

Stem-cell repair system can regenerate any kind of human tissue

Stem-cell repair system can regenerate any kind of human tissue

Kurzweil Network - 06-Apr-2016

Able to regenerate any tissue damaged by injury, disease, or aging. University of New South Wale...

Impatient People Likely To Age Faster

Impatient People Likely To Age Faster

Tech Times - 24-Feb-2016

Shorter telomeres discovered in impatient subjects. Patience of 1,158 undergraduates judged by w...

3D-printing a new lifelike liver tissue for drug screening

3D-printing a new lifelike liver tissue for drug screening

Kurzweil Network - 15-Feb-2016

Closely mimics the human liver’s sophisticated structure and function. Honeycomb pattern using c...

Mechanotherapy regenerates injured muscle tissue

Mechanotherapy regenerates injured muscle tissue

Kurzweil Network - 28-Jan-2016

Could replace or enhance drug- and cell-based regenerative treatments. 2 techniques tested – fer...

Loneliness decreases life expectancy

Loneliness decreases life expectancy

Express - 05-Jan-2016

Social isolation in later life can prove fatal by exacerbating health problems. Friends and fami...

Meet the animal that may live forever

Meet the animal that may live forever

The Avenue Mail - 27-Dec-2015

Tiny hydra – a centimetre-long polyp that inhabits fresh water all over the world – does not show...

Lab-grown kidneys work in animals

Lab-grown kidneys work in animals

BBC - 22-Sep-2015

Jikei University School of Medicine in Tokyo grew kidneys, drainage tube and bladder from pig and...

Synthetic DNA improves human immune system

Synthetic DNA improves human immune system

Independent - 27-Jul-2015

New technique called electroporation opens up microscopic pores in T-cells allowing Crispr/Cas9 e...

Women haven’t always lived longer than men

Women haven’t always lived longer than men

Independent - 07-Jul-2015

Once infectious diseases conquered, deaths from cancer and cardiovascular disease (which affect m...

Acoustic device rapidly isolates circulating tumor cells from blood samples

Acoustic device rapidly isolates circulating tumor cells from blood samples

MIT - 06-Apr-2015

Help predict whether patients’ tumors will metastasize (Video) The study was published in the Pr...

Smart insulin hope for diabetes

Smart insulin hope for diabetes

BBC - 10-Feb-2015

Automatically turns itself on and off to maintain correct blood glucose levels. The study was pu...