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Synthetic DNA improves human immune system

27-Jul-2015

Key points from article :

New technique called electroporation opens up microscopic pores in T-cells allowing Crispr/Cas9 enzymes to enter and replace exact sections of DNA with synthetic, healthy sequences.

Study has genetically-modified cells so they were no longer prone to attack by HIV virus.

Plan is to generate T-cells from a cancer to keep the disease in check.

The study was published in the Proceedings of the National Academy of Sciences.

Mentioned in this article:

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Alexander (Alex) Marson

Director of the UCSF-Gladstone Institute for Genomic Immunology.

Jennifer Doudna

Professor of Biochemistry & Molecular Biology at UC Berkeley

Proceedings of the National Academy of Sciences (PNAS)

Multidisciplinary scientific journal, official journal of the National Academy of Sciences

University of California, San Francisco (UCSF)

Public research university that is part of the University of California system and dedicated entirely to health science

Topics mentioned on this page:
Synthetic Biology