Reason reports back from Rejuvenation Startup Summit 2024
Fight Aging! - 13-May-2024A great summary of 25 speakers who are in various stages of platform building, drug discovery and clinical trials
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Daily news and insights on research, investments and technologies on life extension
We bring together innovators and investors to commercialise the companies that will form the longevity economy.
There are already 100+ rejuvenation biotechs working on unique therapies and building R&D pipelines to increase healthspan and lifespan.
At the same time, all around the world, innovators are releasing nanobots, reprogramming nerve signals and applying AI to create exciting and scalable contributions to human Longevity.
Visit website: https://www.longevity.technology/
Details last updated 12-Sep-2019
A great summary of 25 speakers who are in various stages of platform building, drug discovery and clinical trials
Longevity.Technology releases its annual longevity investment report 2023
Key investors raise funding to support longevity sector
18-Jan-2023
Phil talks about shaping the longevity industry at this Oxford Society of Ageing and Longevity event (FREE)
Longevity Technology discusses senescent cells with Steve Matheson, CEO of Combilytics (YouTube)
A next-gen retinal implant offers new hope for vision loss from macular degeneration
It avoids common delivery problems and enters Phase 1 trials in 2025
Scandinavian biotech targets fibrosis with novel scar-blocking therapies
It uses blood tests to find early health risks and gives personalised advice
Clinical trials are beginning, backed by major investors like Novo Holdings
Targeted protein degradation tackles harmful aggregates while sparing healthy proteins
The biotech firm accelerates clinical trials for TN-201 and TN-401, targeting genetic heart disease
naturalX backs startups reshaping wellness and prevention
The Dutch startup is using ion channel research and advanced tech to develop new treatments
Backed by AI and genetics, Junevity targets age-related diseases
Cutting-edge DNA analysis provides affordable, real-time health insights
Full-body scans drive early detection as Neko expands globally
Early trials show reduced stroke risks and slower progression
Company aims to predict diseases, design therapies, and revolutionise research
It holds potential for treating inflammation, cancer, ageing, and autoimmunity
Dual-action therapies tackling inflammation, metabolism, and neurodegeneration
The company has raised $16 million from investors
Clinical trials have begun on patients with severe kidney disease
Their platform speeds up finding peptides from plants, making healthcare solutions faster
This breakthrough combines large biological datasets and advanced AI tools
Focus areas include gene editing, stem cell therapies, and affordable health solutions
Biotech firm advances osteoporosis therapies and strengthens leadership with key appointment
The treatment "JOTROL" shows promise in cognitive and brain health conditions
Pioneering treatments target underlying mechanisms of age-related diseases like pulmonary fibrosis
Powered by AI, pocdoc accelerates early detection and treatment of chronic diseases
Breakthrough MOTYS moves to phase 3 trials, promising lasting relief for knee osteoarthritis
Integrated glucose monitoring and wearable insights offer a personalized approach to health tracking
Initial focus on lowering cholesterol by targeting NAD+ metabolism
Funding strengthens their capacity to address unmet needs in immune-related diseases
A science-backed approach to healthier, younger-looking skin
NVIDIA will support Genesis in optimizing neural networks for 3D data handling
Initiatives like The Human Phenotype project aim to improve disease diagnostics and predictions
New funding powers AI-driven implants to revolutionize neurological care
Aliada’s BBB technology aims to transform CNS drug delivery
They aim to use AI-driven capsid design for delivery for complex treatments
Their partnership with Calico focuses on age-related disease treatments
Clinical study showed its accuracy, aiming to replace invasive methods like PET scans
They aim to improve patient care and make clinics more trustworthy and effective
They use stem cell technology to regenerate the thymus and aim to slow its natural decline
Shift aims to treat diseases like heart issues and arthritis by addressing aging’s root causes
New proteasome-activating drugs aim to tackle neurodegenerative diseases and extend healthy lifespan
Targeted cell depletion offers a transformative strategy to treat diseases at their root
Clock.bio secures funding to explore genetic pathways for enhancing healthspan
Using AI and biology to speed up drug discovery for healthier ageing
Revolutionizing chronic disease detection through innovative retinal imaging technology
Biotech advances human lactoferrin for better health and longevity
Innovative partnerships aim to develop groundbreaking therapeutics for age-related diseases in cats
The startup leverages its TFome™ platform for rapid and efficient iPSC programming
Phase 2a trial results show positive outcomes among pulmonary fibrosis patients
Madrid becomes Europe's hub for advancing life extension and healthy ageing
ONL pushes forward with innovative treatment to slow vision loss in dry AMD
Early clinical trials showed safety and effectiveness, with more trials planned for 2025
An AI model set to transform drug discovery through cutting-edge molecular predictions
This lab-grown blood could solve donor shortages and help with frequent transfusions
Their aim is to improve preventive health with personalised solutions
Innovative platform accelerates drug discovery for metabolic diseases and more
Cutting-edge AI and laser technology will scale production of personalized regenerative medicines
Boosting fat loss and preserving muscle with cutting-edge mitochondrial therapy
Food for the brain charity launches a test to track brain health through antioxidant levels
Xenotransplantation biotech advances groundbreaking pig kidney transplants
German startup decodes the dark genome, advancing precision medicine
Transforming healthcare with non-invasive, drug-free technology
Extending healthspan and lifespan through personalized, preventive care
New treatment aims to reactivate dormant hair follicles, offering hope for those affected by pattern baldness
This merger aims to deliver quicker results and generate substantial revenue
Approach is based on research from UCSF and could transform how diseases are treated
Funding will primarily be used to advance therapies focused on muscle growth
Unlocks the healing power of placentas for wound care, anti-aging, and beyond
Funding fuels clinical trials of a lead compound, offering hope for liver disease patients
Company is particularly focusing on less invasive treatments for dry AMD and XLRP
Findings indicate that each organ system has its unique ageing trajectory
This could eventually lead to new ways to prevent and treat age-related diseases
Public support can play a crucial role in accelerating progress
Canadian company secures $8M to unlock future regenerative therapies through cryopreservation
The company aims to expand access to this technology for broader healthcare impact
Company aims to improve protein production in genetic medicine
Company is developing therapies for Alzheimer's, Parkinson's, and Rett syndrome
Company's approach involves detecting, correcting, and eliminating damaged cells
This technology could potentially improve the quality of life for many older individuals
Programmable mRNA tech promise precise & safe treatment for disease and age-related conditions
Company is aiming to increase accessibility and affordability
This could potentially revolutionize treatment for severe conditions
Their test, MyPhenome, identifies different types of obesity to tailor treatment plans
Promises faster development and wider access of cell therapies for age-related diseases
Technology aims to make animal studies more efficient, affordable, and humane
AI-powered platform predicts drugs for age-related diseases with 80% accuracy
AI-powered protein design models to transform medicine with next-gen therapeutics
Potentially leading to breakthroughs in managing chronic diseases
Longevity AI app offers personalized guidance based on exercise, diet, and sleep data
Technology promises faster identification of molecules for disease treatment
Longevity.Technology releases its annual longevity investment report 2023
Funding fuels R&D, and collaboration focus on improving diagnosis and treatment options
This investment supports the development of innovative pill-based therapies that use healthy gut bacteria
Funds to advance compounds that target mTORC1 pathway for treating rare and age-related conditions
Company will use machine learning and gut health science to create custom solutions
Company aims to revolutionize preventative healthcare using health tracking system
Company's innovative "liquid cornea" technology shows promise in restoring vision
Developing senotherapeutics to target cellular senescence and treat age-related diseases
iPSC-based therapy set for phase 1 trials to replace lost neurons and modify disease course
Investment fuels its blood-brain barrier-crossing tech for better drug delivery
Its Y100 technology combats hair loss and potentially other age-related issues
Unlocking a new era of comprehensive disease insights and treatment strategies
This powerful AI could transform how we approach disease research
Company aims to transform healthcare by using cutting-edge sugar-based diagnostics
Their main drug, azelaprag, is like a pill that mimics the benefits of exercise
They plan to offer quick full-body scans for $500 in a few years
Their treatment uses implanted cells to calm brain activity and repair damaged networks
Early studies look promising, and the company plans to launch its product soon
They picked RJVA-001, a gene therapy, as their first clinical candidate
Company aims to shift medicine's focus from illness treatment to proactive health optimization
It is already used in 15 countries to detect atrial fibrillation and heart failure
Vesper's main drug, called VES001, is a pill that can reach the brain directly
Company plans to bring their revolutionary Mitopure technology to the world
Shown promising results in preclinical studies and early clinical trials
This, they claim, is safer and more precise than traditional gene editing methods
Fauna's AI platform explores animal data to unlock breakthroughs in weight management
Silicon Valley startup uses personalized data and AI twin to reverse type 2 diabetes and obesity
Company's drug targets the root cause of diseases like Duchenne and COPD
Mitophagy-boosting drug candidate VNA-318 preps for clinical trials
AI-powered data platform empowers early disease detection and proactive care at home
The drugs target obesity, diabetes, and potentially, human longevity
Offers over 20 innovative organ models for realistic testing and collaborating
Company's pipeline targets inflammation, promote healing, and restore quality of life
Using AI to screen natural compounds and create novel longevity products
Company's fasting mimicking technology could revolutionise ageing
Company's "cell-free DNA platform" can detect unexplored cell-free DNA fragments
Ring-type blood pressure monitor to revolutionise hypertension management
Company aims to impact a billion people's lives in five years
Company's quest to decode ageing and develop novel therapies gains momentum
The 8-week trial in the EU focuses on safety and effects on metabolism
Platform decodes brain signals, enabling thousands of applications
Aims to reach an annual production capacity of 500 artificial hearts
Aims for Alzheimer's drugs that target brain's predominant cells, astrocytes
Technology could make mRNA vaccines and therapeutics more effective and safer
Technology could revolutionise the treatment of degenerative diseases
Investing in the next generation of longevity biotech companies
Company's INDUCE-seq platform could revolutionise cell & gene therapy efficiency
How genetic insights could redefine ageing and extend healthy living for all
Technology can successfully measure muscle activity, brain waves, and more
Lead antibody shows promising preclinical data & is set for clinical development
Developing "biological software" for effective and affordable mRNA drug design
A single dose of mRNA therapy could rewind ageing and extend lifespan
Pig plasma therapy could reverse aging in humans
Novel approach to identify ageing targets and fight age-related diseases
Funds to help AI-discovered drugs enter clinical trials and expand its pipeline
By editing RNA instead of DNA, the company aims to treat multiple undruggable genetic diseases safely
Details magic of converting stem cells to any cell type and transplanting them to treat age-related conditions
VitalOne reports 50 lab tests in just 20 minutes and improves accessibility for clinicians & patients
AI-powered research platform to accelerate the processes in drug discovery and development
Highly accurate enzyme-based approach to advance the ability to read, write and manipulate DNA
Ground-breaking technology to advance the development of a bio-engineered thymus & lung disease treatments
Recombinant human collagen based fillers help advance the field regenerative aesthetics
Novel recombinant protein to manufacture biologically fit cells by safely lengthening telomeres
Plans to leverage exclusive Attobody nanobody platform to develop innovative treatments in immunology and oncology
Biotech leverages insights from immunology and cardiology, aiming to dissolve arterial plaques with their flagship asset, BRB-002
Innovative technology combines synthetic biology, genomics, and machine learning to transform the way diseases are diagnosed and treated
Strategic investment aimed at harnessing the power of collaborative innovation and AI in the pursuit of groundbreaking therapeutics
Will use its drug discovery platform to further development of lead compound, IA101
Nir Barzilai brings his expertise to boost the company's mission to extend healthspan by targeting age-related diseases
Aims to extend human healthspan and promote impactful lifestyle changes
AI-powered insights to help doctors prevent disease and boost healthspan
Looking to invest in the longevity industry? Stakes from $100 available on Wefunder platform
Senescent cells have become one of the most promising targets for healthy aging research
Early trials show the drug is safe, and a new study will begin soon
Tissue-specific gene therapies & rejuvenating factors to extend lifespan and combat age-related diseases
Lower the metabolic rate and body heat, longer the lifespan, but has double-edged sword nature to it
Longevity Technology interviews CEO Melanie Goldey
A revolutionary approach in regenerative medicine that could improve quality of life in patients
Those running geroprotective trials, academic researchers, clinical trial could use Cell tree rings
The researchers will not only focus on CVD or cellular aging but the optimal point of intervention
With a global ageing population, the benefits of delaying ageing, even if slightly, are immense
Had success in reducing muscle atrophy and discovered novel class of molecules to target cognitive decline
Report provides analysis on different parts of the brain, including lesions associated with Alzheimer’s disease
Next-generation proteomics technology to accelerate drug discovery and development
Likely to be discussions before stock is removed from sale - and should still be available in the UK
Detecting disease at the earliest stages and reversing it, instead of treating a chronic disease
A quick, bias-free tool empowering early detection and intervention for ageing populations
Cells are already in the right place, just need the right kick to help repair the body when needed
If successful in humans it would improve the outcome of many age-related diseases
Cleara’s novel FOXO4-based treatment approach-ability to eliminate biomarker-positive scarred cells
Looks like it will act as an interface between longevity researchers and clinicians
Initially targeting ischemia-reperfusion injury, TMT has potential to treat multiple age-related diseases
Camera on each petri dish captures healthspan of many worms simultaneously
A single-injection therapy could reverse cartilage loss and transform osteoarthritis treatment
Eliminating senescent cells rejuvenates the heart's capacity for regeneration in mice
Vitalunga to usher the novel drug for hepatocellular carcinoma clinical trials
SIRT6 Activator is a safe way to repair the genetic damages that may occur due to aging
Also announces move to Buck Institute for Research on Aging
Metabolites induce autophagy, stimulate cellular regeneration for healthy ageing
No mention of the Conboys, but it looks like it's based on their plasma dilution research
Big data combined with laboratory automation - the pace of drug discovery is about to take off!
Treatment options for diseases of aging - from the makers of metabolic switch
Targeting age-related diseases, the company's pre-clinical compounds to progress to the clinic
Aeson could prolong lives of patients awaiting a human heart transplant
Lorna Harries details significant breakthroughs at fourth annual Longevity Leaders World Congress
Currently exploring the SIRT6 potential with University of Rochester’s Aging Research Center
Juvenescence and MDI unite to tackle ageing-related fibrosis
Treatment was successful in mice, and now gears up to treat paralyzed humans
Different flavours of rapalogs targeting different age-related conditions
Approaches include senotherapeutics, stem cells and mitochondria. Eye disease is a common first target.
Combining 3D printing and stem cell technologies to develop kidney repair and replacement therapies
Maybe a longevity drug within 5 years, but still lots more research needed into process of ageing
Gold-standard trial included 35 participants taking 1000mg of NR (or placebo) for a week
Could lead to alternative to whole-organ liver transplantation
How emerging science and lifestyle choices could extend life and transform society
Funding will ensure the development of a new immunotherapy for age-related diseases
Seeking funds to develop gene therapies that target ageing in humans and dogs
Invests $82 million in research platforms, aiming to prevent or reverse age-related diseases
Potential oral treatment to prevent sarcopenia and frailty, and extend healthy lifespan
Mentorship and funding support for biotech innovators tackling ageing
Raised $2.5 million to discover and sell life extension products directly to consumers
Eric Merle details Genoskin's technology and its applications in anti-ageing trials
Novel business approach helps people to live longer with good health
Experimental therapy to transfuse healthy mitochondria from multiple donors
From drug discovery to longevity insights, a startup reshapes age-related medicine
A unique treatment approach for ageing; will soon begin trials in animals and human cadaver tissue
Plans to invest in 10 start-ups - any of which could make a step towards longevity escape velocity
The foundation's mission is to make longevity medicine accessible to everyone - fantastic news!
A rapamycin trial testing healthspan improvements in dogs; results may extrapolate to humans as well
Avoiding the spread of fake/misleading health information with ethical marketing
Funds to bring affordable and effective age-related therapies to the public
Safe and potential compound shows disease-modifying effect by removing toxic cholesterol from blood
By investigating self-healing mechanisms in animals, Fauna bio aims to cure human diseases.
Novel gene therapies to prevent the accelerated aging process
Most approaches have their limitations but good progress is being made on several fronts
With an accuracy of 4.7 years it is much more convenient for home testing
Latvian based startup aims for cost-effective research studies, prioritizing study participants
Connecting aspiring longevity founders with mentors to drive innovation in anti-ageing biotech
New collab with Teva Pharmaceuticals to identify drug targets for various diseases
DoNotAge's potent SIRT6 activator improves DNA repair and overall healthspan
Printing brains and transplantable organs to save and improve lives
With the neural signal processing software by Wyss Center, home use of BCI is now closer to reality
Investigational therapy on old mice cleared senescent cells up to 70%, extending life by 20%
Breakthrough in longevity research - cellular energetics may stop or even reverse the ageing process
Kizoo Technology Ventures helps to bring rejuvenation therapies from lab to clinic
Modernizing life insurance to keep its customers healthy and alive
Senolytic Therapy Network aims to take the senotherapeutics from lab to clinic
"Very promising" results from pilot study, with phase 3 clinical trial planned
Edifice Health raises $12M to drive breakthroughs in ageing and inflammation
Jinfiniti's intracellular test measures NAD levels at home with a simple filter-paper kit
Personalized healthy diet plan balancing blood sugar levels is the key to weight loss & overall healthspan
Targets mitochondrial dysfunction - cosmeceuticals on its way to reverse ageing signs in humans
Longer lifespan in old male mice treated with 17‐α‐estradiol, but four other compounds had no effect
Funds to advance gene therapy for age-related macular degeneration & innovative delivery system
Huge database of wildlife gut microbiota could screen potential therapies within days
Advances in longevity pharmacology to revolutionize healthcare with personalized therapies
Reverses immune ageing and can prevent death from coronavirus infection in the elderly
Mitochondrial-based therapy enters IND to tackle IPF and other fibrotic diseases
Working on its first two companies at the moment, aiming at global expansion in the coming years
Advancing technologies for tissue and organ rejuvenation with seed funding from Kizoo
Insilico's novel drug target is prepping for IND studies, expecting to start clinical studies by early 2022
New York-based biotech company with unique approaches to treat age-related diseases
CDP technology enters clinical trials soon to tackle the root cause of heart diseases
Promotes healthy ageing with NR, and is safe and compatible with other supplements
Biotech startup to make stem-cell based therapies to extend and save lives
Trials on mitochondrial transfusion might help tackle many ageing diseases
Supplement with science-based evidence on humans pioneering longevity industry
Results in mice suggest that it can increase median lifespan in humans by 15 years
Instead of targeting specific hallmarks/pillars - they want to target ageing as a whole
Their work will be critical amidst the COVID-19 pandemic - to move into clinical trials soon
Patented compound on clinical trials to prove the benefits on human cognition
12 science-based ingredients act on 9 important processes to slow down ageing
A revolutionary technology research to provide the cure for age-related diseases
Telomere length may not be an accurate indicator of lifespan & health in the elderly
Funding targets early-stage companies and postdoc researchers with unique ideas
Novel approach with gold nanocatalyst technology to reverse neurodegenerative disease
Raised $11M funding which goes into trials and developing functional organs
NOVOS' nutraceutical with free longevity tests plans to launch in January 2021
Deep longevity's psychological clock might help you feel younger and live longer
Tracks your blood glucose in real time - helps optimise diet and exercise
Non invasive sense glucose earring transforms the way patients manage type 1 diabetes
DeepMAge is an accurate ageing clock so far and could be a key in medicine
Avenna's glyhealth alerts practitioners about subclinical chronic inflammation
Lead therapies of BioAge to treat age related diseases enter phase 2 trials
AKG with antiaging benefits is now proved to counter osteoporosis in rodents
Keystone Bio's first ever biologic on the planet to eliminate oral pathogen
Senolytics to treat cancers - study finds correlation between senescence & survival
Set to launch Participatory Evaluation of Aging with Rapamycin for Longevity (PEARL) trial
A study on mice supported ibuprofen for use in neurodegenerative diseases
Restoring NAD homeostasis could help in ageing diseases with telomere dysfunction
Quicksilver uses liposomal nanoparticles to deliver supplements-increases bioavailability
Interoperability has always been problematic in healthcare - we really need to crack it for ageing research
Topical supplement which extends skin span-the period of time your skin is healthy and youthful
Key investors raise funding to support longevity sector
Taisho and Insilico collabs to identify novel targets for senolytic drugs
Discovered in, but not produced from, you-know-what - reduces risk of CVD and cancer
Unfolds inside the body to print cells and tissues - might help bio print organs soon
Circulating CRP and albumin (among other molecules) found to be related to frailty
Peptides reduce inflammaging and improve standardised physical tests
Will be presenting a viable therapeutic strategy using IGF signaling at ARDD 2020
Takes us a step ahead towards regenerating organs for human diseases
Senolytic research is in its nascent stage but no reason why one shouldn't be hopeful
Demonstrates safety as a NAD+ precursor dietary supplement, and also within a drug clinical trial
Nuchido's supplement boosts NAD+ four times higher than other products
Insights can tell what you should and shouldn't do to improve your longevity status
In 60 seconds, can identify ones rate of ageing, BMI, among others
Balance is key to everything especially with human body
Discovery of this homeostatic function just may be the first step but it looks promising
Commercialization of tissue and organ regeneration process for clinical use
Decade-long studies of identical twins were able to reveal connections
Old cells will be more young and beautiful
Gains in fruit flies and roundworms give insights to extend human health and lifespan
Profit from OS-1 could fund development of more products and clinical trials
Maybe we need to develop senoplasts like resveratrol as well as senolytics
Most people (including me!) won't have enough money to attend, but it's good to see more interest in longevity investments
With phase 2 study announced, hopes are up for end-stage renal disease sufferers
Whoever controls the shape of a molecule controls what it can do
Using AI to automatically read data from research paper databases and assess users for 20 diseases
Analysing IgG glycosylation: is it the most accurate measure of biological age?
After a successful phase 1 trial of the CVN424 done one mice, the company started phase 2 studies
Evidence of cellular age reversal demonstrated in this gateway research
Foundation of the new therapies mechanism is to access and control the compounds of CSF
Gray states biohacking is much beyond techniques and tests, rather more simple
UK residents can buy an AgeCurve sample kit and send a saliva sample
New reprogramming technology could provide an alternate source of material needed for therapies
It’s the first human trial focused on reversing ageing with gene therapy
Includes updates on NAPA Therapeutics and BHB Therapeutics
Edwards believes 20–30 years will be added to the average lifespan with none of the ageing diseases
Great intro to life extension's leading advocate - Aubrey predicts radical change within 5 years
TAME trial lead by clinician Dr Nir Barzilai will begin in November