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Trestle Biotherapeutics gathers experts to advance practical use of bioengineered kidneys


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Trestle Biotherapeutics to commercialise a suite of stem cell- and 3D bioprinting-based kidney regenerative technologies.

Innovations developed at Harvard’s Wyss Institute, SEAS, and Brigham.

“We’re thrilled with the opportunity to carry their work forward for patients’ benefit,” - Shepherd, the CEO of Trestle.

“We developed a new biomanufacturing method, SWIFT, that enables the fabrication of vascularized kidney tissues. ” - Jennifer Lewis, Wyss professir at Harvard university.

Created 3D kidney-on-chip models for drug screening and disease modelling.

Joint team of Lewis Lab and Brigham generated vascularised kidney organoids with enhanced nephron maturation in vitro.

Combining these approaches, Trestle will work towards...bioengineered kidney tissue with vital kidney functions.

“It will contribute to kidney repair and replacement therapies that patients. We look forward to seeing this technology rapidly advance to the clinic,” - Donald Ingber, Wyss Founding Director.

Combining 3D printing and stem cell technologies to develop kidney repair and replacement therapies

Mentioned in this article:

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Ben Shepherd

Co-founder and CEO at Trestle Biotherapeutics

Brigham and Women's Hospital

Teaching hospital of Harvard Medical School.

Donald E. Ingber

Founding Director of the Wyss Institute for Biologically Inspired Engineering at Harvard University

Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS)

Engineering school within Harvard University's Faculty of Arts and Sciences.

Harvard University

Private Ivy League research university in Massachusetts

Jennifer Lewis

Wyss Professor of Biologically Inspired Engineering at Harvard University

Trestle Biotherapeutics

Biotechnology company developing bioengineered kidneys for patients with renal diseases