Highlights of Ending Age-Related Diseases 2020
Key points from 20 presentations from world-leading researchers
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CEO of Repair Technologies and founder of Fight Aging
Reason is co-founder and CEO of Repair Biotechnologies. He is the founder and writer of Fight Aging!, a leading blog in the aging biotech community. Reason is also an active angel investor in the space. Previously, Reason was principal software engineer at technology startups. Reason has Masters degrees in Space Physics and Astrophysics.
According to submissions to the US Securities and Exchange Commission, his full legal name is "Reason".
Visit website: https://www.repairbiotechnologies.com/team/reason/
See also: Repair Biotechnologies - Biotechnology company focused on developing drugs for cholesterol and aging-related diseases
Details last updated 30-Sep-2019
31-May-2023 to 02-Jun-2023
Event about aging and aging related diseases organized by Hanson Wade
Reason delivered a keynote on how clearing free cholesterol reverses atherosclerotic plaques
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Hear the latest developments from the leading experts in rejuvenation biotechnology research
05-Nov-2022 to 06-Nov-2022
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13-Jun-2024 to 16-Jun-2024
Event gathering Global Longevity and Rejuvenation community in Dublin by LEV Foundation (Dublin, Ireland)
Live Longer World podcast #1 with Reason as a guest
10-May-2024 to 11-May-2024
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Key points from 20 presentations from world-leading researchers
A great summary of 25 speakers who are in various stages of platform building, drug discovery and clinical trials
Many people believe lots of clinical trials of novel therapeutics targeting mechanisms of aging will start up in the next few years
Some really exciting developments with quite a few in clinical trials
There is a phenomenal amount of work going on across the spectrum of ageing - something is going to work eventually!
CDP technology enters clinical trials soon to tackle the root cause of heart diseases
But Reason is not yet convinced - definitely needs more, and bigger, studies
Disappointing first result - but lessons learnt and plenty of other strategies available
It does seem way to early to be settling for any single type of clock for rejuvenation research
No surprise there is a big overlap in interest in life extension from the cryonics community
Interesting articles and some useful investment opportunities
There have been more negative results in mice than positive - surprising given the press it gets
A great summary of 25 speakers who are in various stages of platform building, drug discovery and clinical trials
While modifying immune cell populations, the drugs also increased ageing biomarkers
Many people believe lots of clinical trials of novel therapeutics targeting mechanisms of aging will start up in the next few years
Some really exciting developments with quite a few in clinical trials
Self-experiment results- detrimental due to frequent doses or simply bad combo
There is a phenomenal amount of work going on across the spectrum of ageing - something is going to work eventually!
One drug doesn't fit all; combination therapies to address multiple ageing processes at once
Neuromuscular junction: A potential therapeutic target in neuromuscular injury
Molecular level benefits observed (inflammation, senescence) as well as physical ones
One treatment does not fit all - diversified gut microbiota needs customizable medicine
Physically active work life and better lifestyle choices linked to long-term survival in men
Restoring gut microbial health can reverse declining age-related immune fitness
Long-term use of this supplement boosts NAD+ levels, lowering the risk of osteoporosis in mice
Disappointingly, no impact was observed on maximum lifespan - still looking for the next bridge
Calorie restriction prevents age-related changes to the gut microbiome in mice
Favorable results in single person experiment calls for a larger and formal research
Disappointing first result - but lessons learnt and plenty of other strategies available
Causation vs correlation to be confirmed - but death affects ALL cells in the body, not just YOUR cells
Given senolytics are unlikely to ever clear every senescent cell, exercise will still minimise bad effects of those remaining
Perhaps all the benefits come their their increased physical activity - worth further investigation