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Ageing Research News

PEDF protein, found in young blood, rejuvenates aging cells and tissues in mice

Live Forever Club - 24-May-2024

More research is needed, but this discovery offers hope for anti-aging therapies

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Aging measured by randomness in cells, study finds

CECAD Cluster of Excellence for Aging Research - 09-May-2024

Random cellular chaos offers new hope for anti-ageing interventions

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Google DeepMind's AlphaFold3 predicts how life's building blocks interact

The Guardian - 08-May-2024

The breakthrough could revolutionize drug discovery and disease treatment

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Scientists zero in on molecules that could significantly extend healthy lifespan

Live Forever Club - 07-May-2024

Offering hope for longer, healthier lives for future healthcare

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Newly discovered enzyme plays vital role in stem cell longevity

Baylor College of Medicine - 30-Apr-2024

This discovery could have important implications for understanding healthy ageing processes

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Ageing immune systems linked to malfunctioning molecules within key cells

Medical Xpress - 26-Apr-2024

Research explain why we become more vulnerable to infections as we age

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Some everyday medications could lengthen life, while others like opioids might pose risks

Live Forever Club - 22-Apr-2024

Surprisingly, metformin does not reduce death risk

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Body's repair system falters with age as stem cells lose their regenerative power

Live Forever Club - 12-Apr-2024

Machine learning reveals widespread decline in stem cell potency with age

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Tardigrade protein helps human cells mimic survival superpower

Futurism - 02-Apr-2024

Research reveals a potential way to make human cells more resistant to stress

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Somatic mutations: Do these DNA changes hold the secrets to longevity?

Live Forever Club - 31-Mar-2024

The gradual buildup of DNA mutations may hold clues on how to combat age-related diseases

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Lifespan.io interviews David Sinclair about his Information Theory of Aging and much more

Lifespan.io (LEAF) - 22-Mar-2024

Backup code: ageing cells from epigenetic changes could potentially be reset to a youthful state

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Extending quality life years: insights from the Global Healthspan Summit 2023

Live Forever Club - 16-Mar-2024

Event focused on extending quality life years through scientific innovation

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UK study finds 14 prescription meds possibly linked to longer life

Lifespan.io (LEAF) - 15-Mar-2024

Viagra, cholesterol meds & estrogen replacements linked to longevity, but further research needed

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A protein called APOB, key to blood fat control, could influence your lifespan

Live Forever Club - 25-Feb-2024

Lowering APOB could potentially delay age-related diseases like Alzheimer's

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New research links DNA damage to incomplete gene transcription in aging

Lifespan.io (LEAF) - 15-Feb-2024

DNA damage accumulated with age worsens gene expression, affecting lifespan-determining pathways

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Scientists grew tiny heart-like tissues with CVD in a lab dish, using stem cells

University of East London (UEL) - 13-Feb-2024

Research has the potential to revolutionise heart disease treatment in older adults

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Northwestern University launches the Human Longevity Laboratory to fight ageing

Northwestern University - 12-Feb-2024

Researchers will work finding ways to live healthier and longer

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Mouse models get a major boost as UK funds research on dementia and ageing

UK Research and Innovation (UKRI) - 12-Feb-2024

This collaboration aims to unlock the secrets of ageing and develop new therapies

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AI and quantum computing join forces to crack the code of life

EurekAlert! - 26-Jan-2024

This "physics-guided AI" approach promises deeper insights than current methods

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The Hevolution Foundation's report proposes a radical shift in healthcare

Live Forever Club - 23-Jan-2024

Report suggests that our focus needs to move from lifespan to healthspan

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Once helpful immune alarm bells, inflammasomes now fuel chronic diseases

Live Forever Club - 18-Jan-2024

Researchers are developing new treatments to turn down the inflammatory response

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Cambridge scientists are making significant strides in understanding ageing

Cambridge Independent - 05-Jan-2024

Promising leads for potential anti-ageing interventions in the next decade

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Ageing may be driven by disruptions in electrical signals between cells

Live Forever Club - 05-Jan-2024

Bioelectric signals could even promote tissue regeneration

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A cellular protein called HKDC1 tidies up mitochondria and lysosomes

Interesting Engineering - 01-Jan-2024

This discovery paves the way for potential anti-ageing therapies

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El País interviews Altos Labs’ principal investigator Pura Muñoz Cánoves

El País - 27-Dec-2023

Altos labs with a $3-billion budget pave the way for reversing aging and extending healthy lifespan

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LEV Foundation announces plan for second Robust Mouse Rejuvenation study (RMR2)

Live Forever Club - 22-Dec-2023

Will look at combinations of partial cellular reprogramming, mesenchymal stem cells, serum albumin and deuterated fatty acids

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Cambridge researchers continuously explore novel approaches to improve healthspan

University of Cambridge - 20-Dec-2023

Quest for people to live healthily for as long as possible will inevitably result in longer lives

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Antioxidants and seasickness meds show promise in extending life in male mice

Live Forever Club - 11-Dec-2023

The gender-specific effects observed underscore the complexity of ageing

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Our genes push for early babies, but at the cost of living shorter lives

University of Michigan - 08-Dec-2023

But don't stress, modern factors like healthcare and lifestyle have a bigger impact than genes

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The reign of dinosaurs may have shaped how humans and other mammals age

Live Forever Club - 05-Dec-2023

Dinosaur-era pressures may have led to the loss of longevity genes

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SIRT2 overexpression does not significantly impact lifespan in mice

Live Forever Club - 05-Dec-2023

Study suggests a more nuanced role of this protein in the ageing

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XPRIZE Launches a $101 Million Healthspan Competition

Live Forever Club - 29-Nov-2023

10 years of functional age-reversal in 65-80 year olds within the next 7 years... bring it on!!!

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C. elegans: A tiny worm that can help scientists understand how ageing works

Live Forever Club - 20-Nov-2023

The research could lead to new ways to slow down ageing in humans

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New mice with human-like telomeres could help us fight ageing and cancer

The Jerusalem Post - 30-Oct-2023

Model could be used to study the role of telomere length in several diseases

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Frontier Bio's lab-grown blood vessel tech revolutionizes medical device testing

3DPrint.com - 24-Oct-2023

Promises a future without animal testing and the need for organ donors

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Unravelling the complexities of aging: A comprehensive database of aging factors

Live Forever Club - 23-Oct-2023

A deep dive into the AgingReG curated database of aging regulatory relationships in humans

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New brain atlas reveals thousands of previously unknown cell types

New Scientist - 12-Oct-2023

Could lead to new insights into neurological and mental health conditions

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Largest centenarian blood study identifies key factors for long life

Independent - 10-Oct-2023

Lower levels of glucose, creatinine, and uric acid linked to increased longevity

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Buck Institute and Phenome Health team up to advance scientific wellness

Buck Institute - 27-Sep-2023

Collaboration of data and discovery to extend healthspan for everyone

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Lifespan.io reports back from Aging Research and Drug Discovery Meeting (ARDD 2023)

Lifespan.io (LEAF) - 26-Sep-2023

Key points from Arkadi Mazin's summary of 5 days of talks by geroscientists and biotech leaders

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The Chan Zuckerberg Initiative to launch AI supercomputer for decoding biology

GEN News - 22-Sep-2023

New AI technologies promise to accelerate scientific discoveries and cure diseases by the end of the century

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Naked mole rats' secret to long life could be unlocked for humans

University of Rochester - 23-Aug-2023

Scientists transfer the longevity gene to mice, extending their lifespan by 4.4%

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Human cell's memory erased to resemble embryonic stem cells

EurekAlert! - 16-Aug-2023

New reprogramming method addresses epigenetic challenges & sets a standard for cell therapy research

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Human heart on a microchip: A revolutionary new tool for medical research

Methuselah Foundation - 14-Aug-2023

Organ on a chip may be more successful than mice models in translating science to the clinic

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New, publicly available "unknome" database for poorly studied proteins

New Scientist - 08-Aug-2023

Many neglected proteins/genes have essential function, finding out may accelerate future research

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Signalling pathways in aged cells found to impair the ability to repair and regenerate muscle cells

Independent - 07-Aug-2023

Study results offer insights on future drug discovery for disease related to muscle ageing

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Epiterna receives 10m euros to extend lifespans of pets and people

Sifted - 01-Aug-2023

Planning to test its therapies in dogs next year, with human treatments expected in the near future

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Automating genetics research: A robotic system for handling C. elegans (with video)

Phys.org - 06-Jul-2023

WormPicker takes on time-consuming tasks including inspection, movement between petri dishes and genetic crossing

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Reason reports back from Age-Related Disease Therapeutics Summit 2023

Fight Aging! - 16-Jun-2023

Many people believe lots of clinical trials of novel therapeutics targeting mechanisms of aging will start up in the next few years

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Hevolution Foundation allocates over $20 Million to promote aging research through HF-AGE grant program

Live Forever Club - 23-May-2023

Nine innovative projects, spread over seven US institutions, set to receive funding

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Longevity Med Summit - Best of the Rest

Live Forever Club - 19-May-2023

Key points from more of the excellent speakers at the summit

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Summary of Aubrey de Grey presentation at Longevity Med Summit

Live Forever Club - 16-May-2023

A quick introduction to the preventative maintenance approach, LEV Foundation and Robust Mouse Rejuvenation

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Summary of Max Unfried presentation at Longevity Med Summit

Live Forever Club - 12-May-2023

VitaDAO has already funded 17 projects - including research areas not supported by traditional government agencies

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Pioneering longevity researcher joins SIRTLab to accelerate aging interventions

Longevity Technology - 09-May-2023

Nir Barzilai brings his expertise to boost the company's mission to extend healthspan by targeting age-related diseases

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Unraveling the mysteries of aging: Epigenetic damage and the limits of cellular repair

Live Forever Club - 09-May-2023

Novel theory of biological systemic ageing suggests epigenetic ageing is inevitable

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Live Forever Club becomes latest member of International Longevity Alliance (ILA)

Live Forever Club - 03-May-2023

Organisations share a common mission of healthy longevity for all through scientific research

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Nuffield Council on Bioethics publishes its "The future of ageing" report

Nuffield Council on Bioethics - 25-Apr-2023

The report sets out an ethical framework and recommendations for research and innovation related to ageing

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Maximon Longevity Prize 2023: Awarding Innovative Research Projects that Extend Human Lifespan

Maximon - 20-Apr-2023

Apply now to showcase your translational longevity research and win CHF 50,000

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Ageing speeds up gene reading, reducing its accuracy

University of Cologne - 12-Apr-2023

Calorie restriction may extend lifespan by improving the quality of gene transcription

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Meta-analysis studies relate autophagy mechanism with exercise in humans

Lifespan.io (LEAF) - 22-Mar-2023

The type of exercise can effect autophagy in humans, that in return can be an anti-aging strategy

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Study shows it is critical for stem cells to prevent stress to preserve their health and longevity

News Medical - 21-Mar-2023

Therapeutics to boost regulation of protein homeostasis may be beneficial across multiple organs and pathologies

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Cellular ageing signs emerge earlier in women than men

New Scientist - 19-Mar-2023

Machine learning analysis of millions of biopsy reports has potential implications for disease risk and treatment

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Hypothalamic protein called menin found to regulate ageing and cognitive deficits

Interesting Engineering - 16-Mar-2023

Supplementing with the amino acid D-serine may reverse some anti-ageing effects

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Lifespan.io interviews George Church about recent research and future anti-ageing treatments

Lifespan.io (LEAF) - 14-Mar-2023

Is involved in many longevity companies ranging from improving gene therapy delivery to supplements

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Five Alarm Bio raises seed investment to discover small molecule anti-aging drugs

Cambridge Network - 27-Feb-2023

No drug candidates yet, but great to see investors willing to support a broad attack on ageing

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Analysis of gut microbiome relationship with longevity

Live Forever Club - 12-Feb-2023

A strong genetic correlation between healthy diverse gut microbiome and healthy ageing was found

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Effects of intermittent fasting: An exploration

Live Forever Club - 31-Jan-2023

12 months of IF results in a range of biomarker improvements, but no significant reduction in inflammatory markers

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Open genes-comprehensive database of genes associated with aging and longevity

Lifespan.io (LEAF) - 24-Jan-2023

Open gene database simplifies the search for potential aging therapy targets

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Lifespan.io summarises the proceedings of the Buck Institute's Longevity Summit

Lifespan.io (LEAF) - 20-Jan-2023

Another reminder of the amount of research, with multiple approaches, about to go into clinical trials

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Dissociation of longevity targeted cell reprogram and somatic identity loss: An exploration

Live Forever Club - 17-Jan-2023

Most genes regulating cellular rejuvenation were not related to the increased occurrence of cancer

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Longevity Technology speaks to BioAge's CEO about clinical trial progress

Longevity Technology - 06-Jan-2023

Had success in reducing muscle atrophy and discovered novel class of molecules to target cognitive decline

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Genome length and the relationship with ageing: An analysis

Live Forever Club - 06-Jan-2023

Identifies a new target for ageing therapeutics - maintaining the abundance of long RNA transcripts

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Nuclear homeostasis contributes to promote longevity and fertility, IMBB scientists

Institute of Molecular Biology and Biotechnology (IMBB-FORTH) - 27-Dec-2022

Cells fundamental quality control mechanism to safeguard the nucleus-promote longevity and fertility

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Cellular Senescence Network (SenNet) to identify and characterize senescent cells

Nature Aging - 20-Dec-2022

Grand plan includes creation of imaging datasets, new tools, techniques, and biomarker panels

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SIRT6: Ageing, Metabolism, and Cardiovascular Diseases - A Review

Live Forever Club - 20-Dec-2022

SIRT6 has a vital role in cell metabolism which could lead to therapeutics for controlling senescence

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Exploring cellular enlargement as a new hallmark of aging

Live Forever Club - 12-Dec-2022

Size of various cells (including red blood, adipocytes, brain, heart) is seen to increase with age-related diseases

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Five Alarm Bio to develop drug treatment not to cure ageing but improve healthy lifespan

Cambridge Independent - 04-Nov-2022

The company aims at treatments for a range of diseases associated with ageing and disabilities

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Reprogramming by cellular rejuvenation in mice increases lifespan and health

Lifespan.io (LEAF) - 01-Nov-2022

Partial reprogramming extends healthspan and lifespan by single or lifelong treatment

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Senolytics-a risky proposition in aging and repair mechanisms

Lifespan.io (LEAF) - 19-Oct-2022

The study is a caution for scientists engaging in self-experimentation with senolytics

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Reason reports back from October's Rejuvenation Startup Summit

Fight Aging! - 19-Oct-2022

Some really exciting developments with quite a few in clinical trials

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Calico-Terray Therapeutics collaborate to discover and advance therapeutics for diseases of aging

Calico - 12-Oct-2022

Terray’s novel microarray technology, combines wet lab and computer-driven drug development

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Same chronological age women are biologically younger than the men

News Medical - 10-Oct-2022

Differences in biological aging between men and women - frequent smoking and larger body size of men

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Ageing-related drug screening made easy and reproducible with automated tech

Longevity Technology - 18-Aug-2022

Camera on each petri dish captures healthspan of many worms simultaneously

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Mitophagy activators shown to increase lifespan and healthspan in C.elegans

Longevity Technology - 10-Aug-2022

Vitalunga to usher the novel drug for hepatocellular carcinoma clinical trials

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SIRT6, the longevity sirtuin proven to enhance healthy longevity

Longevity Technology - 03-Aug-2022

SIRT6 Activator is a safe way to repair the genetic damages that may occur due to aging

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Age-related changes in retina linked to decline in 'youth' protein

National Eye Institute (NEI) - 18-Jul-2022

Aging associated retinal disorders linked to loss of protective protein

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Ageing versus longevity: epigenetic age correlated with only a few ageing hallmarks

Live Forever Club - 08-Jun-2022

Mitochondrial dysfunction & stem cell exhaustion accelerated the epigenetic clock, but senescent cells & telomere length did not

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Not just vision - diet and eye health is linked to aging in fruitflies

Buck Institute - 07-Jun-2022

Staring at gadget screens at night affects circadian clock and in turn lifespan

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Hevolution Foundation to spend $1 billion annually on the biology of aging

MIT Technology Review - 07-Jun-2022

Considering funding a $100 million age reversal X Prize and the TAME(metformin) trial

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New algorithm recognises senescent cells using physical morphology

Lifespan.io (LEAF) - 26-May-2022

in vivo analysis in mice confirms the imaging results against p21 biomarker

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Buck researchers discover mitochondrial protein that can increase lifespan

Buck Institute - 18-May-2022

In yeast, increasing Tom70 delays ageing related mitochondrial dysfunction

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Lifespan.io interviews João Pedro de Magalhães about theories of, and curing, ageing

Lifespan.io (LEAF) - 13-May-2022

The one thing I hope he's wrong about is that it won't happen in his lifetime - we just need some exponential oomph!

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Anti-ageing substance in sea squirts improved brain health in older mice

Neuroscience News - 11-May-2022

Plasmalogen supplement reversed ageing signs in mice; might as well keeps you young

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The Observer interviews Morgan Levine about ageing and her move to Altos Labs

The Guardian - 07-May-2022

When it comes to lifespan, you cannot blame 100% on genetics, just 10-30%

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First ever organ-on-a-chip functions like the human's body

Columbia Engineering - 27-Apr-2022

Opens way for personalized therapy, drug testing, and clinical extrapolation

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Mammals have similar number of DNA mutations whatever their lifespan

BBC - 14-Apr-2022

Shorter lived animals have higher rate of mutations - could explain lower rates of cancer in larger mammals

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SENISCA to reverse senescence by targeting RNA splicing patterns

Longevity Technology - 08-Apr-2022

Lorna Harries details significant breakthroughs at fourth annual Longevity Leaders World Congress

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Brain charts: showing the incredible growing and shrinking brain ability

University of Cambridge - 06-Apr-2022

Mapping the brain and creating charts could be used as a helpful clinical tool for other clinicians, psychiatrists and researchers

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Genflow's sirtuin gene therapy can make old liver young again

Longevity Technology - 29-Mar-2022

Currently exploring the SIRT6 potential with University of Rochester’s Aging Research Center

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Senior UCLA scientists public states aim to fight aging to impact numerous diseases

University of California, Los Angeles (UCLA) - 24-Mar-2022

Great to see the concept of reversing aging becoming a mainstream ambition - it hasn't always been that way!

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