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Ageing Research News

Generous donations propel next phase of mouse rejuvenation research

LEV Foundation - 01-Oct-2024

Support from Didier Coeurnelle enables groundbreaking longevity studies to advance

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What supercentenarians reveal about living beyond 110 years of age

Live Forever Club - 29-Sep-2024

Their survival might even be connected to the time of year they’re born or die

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Breakthrough anti-ageing drug preserves key cellular processes

Medical Xpress - 25-Sep-2024

Researchers discover a compound that slows ageing by boosting protein maintenance

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Cracking the code of wrinkles: insights from human tissue models

Pohang University of Science and Technology (POSTECH) - 19-Sep-2024

Groundbreaking research reveals how compressive forces and dehydration drive wrinkle formation

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Unlocking longevity: the discovery of OSER1

Neuroscience News - 05-Sep-2024

A breakthrough protein linked to ageing could lead to new treatments for age-related diseases

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Blood biomarkers offer insights into ageing, but their reliability varies

Live Forever Club - 05-Sep-2024

Epigenetic clocks show promise for studying ageing in both mice and humans

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Food dye turns tissues transparent, revolutionizing medical imaging

The Guardian - 05-Sep-2024

Food dye reveals hidden organs and veins by making tissues transparent

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Changes in IgG glycosylation due to ageing influence immune responses

Live Forever Club - 04-Sep-2024

Diseases like Alzheimer's and cardiovascular conditions show distinct IgG glycosylation

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Cortex Discovery unveils first AI-discovered drug to extend lifespan

Cortex Discovery - 01-Sep-2024

CortexW1 boosts lifespan of worms by 33%, highlighting AI's role in longevity research

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Dr. Sajad Zalzala reports on PEARL rapamycin trial results

Live Forever Club - 28-Aug-2024

Safety of rapamycin looks good and lean muscle mass among biomarkers trending towards improvement

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Gut fungi in long-lived people may hold clues to longevity and healthy ageing

Live Forever Club - 20-Aug-2024

The fungi might play a role in longevity by interacting with beneficial bacteria

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Doubts raised about effectiveness of anti-ageing research for humans

The EMBO Journal - 16-Aug-2024

Large investments continue, but human research outcomes remain uncertain

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Ageing isn’t gradual but happens in two major bursts at ages 44 and 60

The Guardian - 14-Aug-2024

The findings may explain why health problems often increase at these ages

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Understanding the immune system's journey from birth to old age

Live Forever Club - 27-Jul-2024

Advanced technologies like flow cytometry provide deeper insights

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Lord Lebedev: Longevity research could benefit the UK's ageing population

Evening Standard - 23-Jul-2024

Research could significantly boost the UK economy and healthcare system

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Newly developed epigenetic clock 'CellPopAge' can accurately measure cellular age

Live Forever Club - 21-Jul-2024

Study also identified that compounds Torin2 and dactolisib extend Drosophila lifespan

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Breakthrough drug extends lifespan of mice by 25% - safety already demonstrated in humans

BBC - 17-Jul-2024

Interleukin-11 antibody shows promise as an anti-ageing treatment that could revolutionise human longevity

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Gut microbes influence our immunity and overall health from birth to old age

Live Forever Club - 06-Jul-2024

Balanced diets improve gut health, while processed foods harm it

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International Longevity Alliance keeps growing with more organisations from around the world

Live Forever Club - 04-Jul-2024

Transhumanists Africa is the latest federated member to join the longevity-promoting alliance

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Burning calories linked to longer life in mice- could exercise be the key for humans too?

Proceedings of the National Academy of Sciences (PNAS) - 21-Jun-2024

Energy expenditure, not just eating less, lead to 20% longer life in mice

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Drugs like metformin and resveratrol might hold the key to extending human lifespan

Live Forever Club - 21-Jun-2024

With the ongoing increase in human life expectancy, the quest for effective anti-aging solutions is accelerating

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Ageing research funding: UK scientists call for urgent action

Longevity Technology - 13-Jun-2024

Public support can play a crucial role in accelerating progress

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Low α-Klotho levels raise the risk of heart problems and death

Live Forever Club - 13-Jun-2024

This finding could lead to new ways to predict and prevent age-related illnesses

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Eye muscles known as 'extraocular muscles' are remarkably resistant to aging

Live Forever Club - 30-May-2024

Findings hint at potential breakthroughs in muscle therapy

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PEDF protein, found in young blood, rejuvenates aging cells and tissues in mice

Live Forever Club - 24-May-2024

More research is needed, but this discovery offers hope for anti-aging therapies

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Aging measured by randomness in cells, study finds

CECAD Cluster of Excellence for Aging Research - 09-May-2024

Random cellular chaos offers new hope for anti-ageing interventions

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Google DeepMind's AlphaFold3 predicts how life's building blocks interact

The Guardian - 08-May-2024

The breakthrough could revolutionize drug discovery and disease treatment

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Scientists zero in on molecules that could significantly extend healthy lifespan

Live Forever Club - 07-May-2024

Offering hope for longer, healthier lives for future healthcare

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Newly discovered enzyme plays vital role in stem cell longevity

Baylor College of Medicine - 30-Apr-2024

This discovery could have important implications for understanding healthy ageing processes

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Ageing immune systems linked to malfunctioning molecules within key cells

Medical Xpress - 26-Apr-2024

Research explain why we become more vulnerable to infections as we age

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Some everyday medications could lengthen life, while others like opioids might pose risks

Live Forever Club - 22-Apr-2024

Surprisingly, metformin does not reduce death risk

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Body's repair system falters with age as stem cells lose their regenerative power

Live Forever Club - 12-Apr-2024

Machine learning reveals widespread decline in stem cell potency with age

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Tardigrade protein helps human cells mimic survival superpower

Futurism - 02-Apr-2024

Research reveals a potential way to make human cells more resistant to stress

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Somatic mutations: Do these DNA changes hold the secrets to longevity?

Live Forever Club - 31-Mar-2024

The gradual buildup of DNA mutations may hold clues on how to combat age-related diseases

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Lifespan.io interviews David Sinclair about his Information Theory of Aging and much more

Lifespan.io (LEAF) - 22-Mar-2024

Backup code: ageing cells from epigenetic changes could potentially be reset to a youthful state

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Extending quality life years: insights from the Global Healthspan Summit 2023

Live Forever Club - 16-Mar-2024

Event focused on extending quality life years through scientific innovation

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UK study finds 14 prescription meds possibly linked to longer life

Lifespan.io (LEAF) - 15-Mar-2024

Viagra, cholesterol meds & estrogen replacements linked to longevity, but further research needed

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A protein called APOB, key to blood fat control, could influence your lifespan

Live Forever Club - 25-Feb-2024

Lowering APOB could potentially delay age-related diseases like Alzheimer's

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Notre Dame tackles neurodegeneration with CZI support

News Medical - 21-Feb-2024

Exploring how ageing genes impact brain health and disease

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New research links DNA damage to incomplete gene transcription in aging

Lifespan.io (LEAF) - 15-Feb-2024

DNA damage accumulated with age worsens gene expression, affecting lifespan-determining pathways

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Scientists grew tiny heart-like tissues with CVD in a lab dish, using stem cells

University of East London (UEL) - 13-Feb-2024

Research has the potential to revolutionise heart disease treatment in older adults

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Northwestern University launches the Human Longevity Laboratory to fight ageing

Northwestern University - 12-Feb-2024

Researchers will work finding ways to live healthier and longer

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Mouse models get a major boost as UK funds research on dementia and ageing

UK Research and Innovation (UKRI) - 12-Feb-2024

This collaboration aims to unlock the secrets of ageing and develop new therapies

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AI and quantum computing join forces to crack the code of life

EurekAlert! - 26-Jan-2024

This "physics-guided AI" approach promises deeper insights than current methods

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The Hevolution Foundation's report proposes a radical shift in healthcare

Live Forever Club - 23-Jan-2024

Report suggests that our focus needs to move from lifespan to healthspan

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Once helpful immune alarm bells, inflammasomes now fuel chronic diseases

Live Forever Club - 18-Jan-2024

Researchers are developing new treatments to turn down the inflammatory response

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Cambridge scientists are making significant strides in understanding ageing

Cambridge Independent - 05-Jan-2024

Promising leads for potential anti-ageing interventions in the next decade

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Ageing may be driven by disruptions in electrical signals between cells

Live Forever Club - 05-Jan-2024

Bioelectric signals could even promote tissue regeneration

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A cellular protein called HKDC1 tidies up mitochondria and lysosomes

Interesting Engineering - 01-Jan-2024

This discovery paves the way for potential anti-ageing therapies

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El País interviews Altos Labs’ principal investigator Pura Muñoz Cánoves

El País - 27-Dec-2023

Altos labs with a $3-billion budget pave the way for reversing aging and extending healthy lifespan

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LEV Foundation announces plan for second Robust Mouse Rejuvenation study (RMR2)

Live Forever Club - 22-Dec-2023

Will look at combinations of partial cellular reprogramming, mesenchymal stem cells, serum albumin and deuterated fatty acids

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Cambridge researchers continuously explore novel approaches to improve healthspan

University of Cambridge - 20-Dec-2023

Quest for people to live healthily for as long as possible will inevitably result in longer lives

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Antioxidants and seasickness meds show promise in extending life in male mice

Live Forever Club - 11-Dec-2023

The gender-specific effects observed underscore the complexity of ageing

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Our genes push for early babies, but at the cost of living shorter lives

University of Michigan - 08-Dec-2023

But don't stress, modern factors like healthcare and lifestyle have a bigger impact than genes

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The reign of dinosaurs may have shaped how humans and other mammals age

Live Forever Club - 05-Dec-2023

Dinosaur-era pressures may have led to the loss of longevity genes

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SIRT2 overexpression does not significantly impact lifespan in mice

Live Forever Club - 05-Dec-2023

Study suggests a more nuanced role of this protein in the ageing

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XPRIZE Launches a $101 Million Healthspan Competition

Live Forever Club - 29-Nov-2023

10 years of functional age-reversal in 65-80 year olds within the next 7 years... bring it on!!!

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C. elegans: A tiny worm that can help scientists understand how ageing works

Live Forever Club - 20-Nov-2023

The research could lead to new ways to slow down ageing in humans

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New mice with human-like telomeres could help us fight ageing and cancer

The Jerusalem Post - 30-Oct-2023

Model could be used to study the role of telomere length in several diseases

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Frontier Bio's lab-grown blood vessel tech revolutionizes medical device testing

3DPrint.com - 24-Oct-2023

Promises a future without animal testing and the need for organ donors

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Unravelling the complexities of aging: A comprehensive database of aging factors

Live Forever Club - 23-Oct-2023

A deep dive into the AgingReG curated database of aging regulatory relationships in humans

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New brain atlas reveals thousands of previously unknown cell types

New Scientist - 12-Oct-2023

Could lead to new insights into neurological and mental health conditions

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Largest centenarian blood study identifies key factors for long life

Independent - 10-Oct-2023

Lower levels of glucose, creatinine, and uric acid linked to increased longevity

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Buck Institute and Phenome Health team up to advance scientific wellness

Buck Institute - 27-Sep-2023

Collaboration of data and discovery to extend healthspan for everyone

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Lifespan.io reports back from Aging Research and Drug Discovery Meeting (ARDD 2023)

Lifespan.io (LEAF) - 26-Sep-2023

Key points from Arkadi Mazin's summary of 5 days of talks by geroscientists and biotech leaders

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The Chan Zuckerberg Initiative to launch AI supercomputer for decoding biology

GEN News - 22-Sep-2023

New AI technologies promise to accelerate scientific discoveries and cure diseases by the end of the century

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2024 Breakthrough Prize honors medical innovations transforming lives

Breakthrough Prize Foundation - 14-Sep-2023

Game-changing treatments for cancer, cystic fibrosis, and parkinson’s

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Naked mole rats' secret to long life could be unlocked for humans

University of Rochester - 23-Aug-2023

Scientists transfer the longevity gene to mice, extending their lifespan by 4.4%

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Human cell's memory erased to resemble embryonic stem cells

EurekAlert! - 16-Aug-2023

New reprogramming method addresses epigenetic challenges & sets a standard for cell therapy research

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Human heart on a microchip: A revolutionary new tool for medical research

Methuselah Foundation - 14-Aug-2023

Organ on a chip may be more successful than mice models in translating science to the clinic

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New, publicly available "unknome" database for poorly studied proteins

New Scientist - 08-Aug-2023

Many neglected proteins/genes have essential function, finding out may accelerate future research

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Signalling pathways in aged cells found to impair the ability to repair and regenerate muscle cells

Independent - 07-Aug-2023

Study results offer insights on future drug discovery for disease related to muscle ageing

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Epiterna receives 10m euros to extend lifespans of pets and people

Sifted - 01-Aug-2023

Planning to test its therapies in dogs next year, with human treatments expected in the near future

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Automating genetics research: A robotic system for handling C. elegans (with video)

Phys.org - 06-Jul-2023

WormPicker takes on time-consuming tasks including inspection, movement between petri dishes and genetic crossing

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Reason reports back from Age-Related Disease Therapeutics Summit 2023

Fight Aging! - 16-Jun-2023

Many people believe lots of clinical trials of novel therapeutics targeting mechanisms of aging will start up in the next few years

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Hevolution Foundation allocates over $20 Million to promote aging research through HF-AGE grant program

Live Forever Club - 23-May-2023

Nine innovative projects, spread over seven US institutions, set to receive funding

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Longevity Med Summit - Best of the Rest

Live Forever Club - 19-May-2023

Key points from more of the excellent speakers at the summit

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Summary of Aubrey de Grey presentation at Longevity Med Summit

Live Forever Club - 16-May-2023

A quick introduction to the preventative maintenance approach, LEV Foundation and Robust Mouse Rejuvenation

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Summary of Max Unfried presentation at Longevity Med Summit

Live Forever Club - 12-May-2023

VitaDAO has already funded 17 projects - including research areas not supported by traditional government agencies

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Pioneering longevity researcher joins SIRTLab to accelerate aging interventions

Longevity Technology - 09-May-2023

Nir Barzilai brings his expertise to boost the company's mission to extend healthspan by targeting age-related diseases

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Unraveling the mysteries of aging: Epigenetic damage and the limits of cellular repair

Live Forever Club - 09-May-2023

Novel theory of biological systemic ageing suggests epigenetic ageing is inevitable

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Live Forever Club becomes latest member of International Longevity Alliance (ILA)

Live Forever Club - 03-May-2023

Organisations share a common mission of healthy longevity for all through scientific research

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Nuffield Council on Bioethics publishes its "The future of ageing" report

Nuffield Council on Bioethics - 25-Apr-2023

The report sets out an ethical framework and recommendations for research and innovation related to ageing

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Maximon Longevity Prize 2023: Awarding Innovative Research Projects that Extend Human Lifespan

Maximon - 20-Apr-2023

Apply now to showcase your translational longevity research and win CHF 50,000

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Ageing speeds up gene reading, reducing its accuracy

University of Cologne - 12-Apr-2023

Calorie restriction may extend lifespan by improving the quality of gene transcription

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Meta-analysis studies relate autophagy mechanism with exercise in humans

Lifespan.io (LEAF) - 22-Mar-2023

The type of exercise can effect autophagy in humans, that in return can be an anti-aging strategy

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Study shows it is critical for stem cells to prevent stress to preserve their health and longevity

News Medical - 21-Mar-2023

Therapeutics to boost regulation of protein homeostasis may be beneficial across multiple organs and pathologies

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Cellular ageing signs emerge earlier in women than men

New Scientist - 19-Mar-2023

Machine learning analysis of millions of biopsy reports has potential implications for disease risk and treatment

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Hypothalamic protein called menin found to regulate ageing and cognitive deficits

Interesting Engineering - 16-Mar-2023

Supplementing with the amino acid D-serine may reverse some anti-ageing effects

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Lifespan.io interviews George Church about recent research and future anti-ageing treatments

Lifespan.io (LEAF) - 14-Mar-2023

Is involved in many longevity companies ranging from improving gene therapy delivery to supplements

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Five Alarm Bio raises seed investment to discover small molecule anti-aging drugs

Cambridge Network - 27-Feb-2023

No drug candidates yet, but great to see investors willing to support a broad attack on ageing

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Analysis of gut microbiome relationship with longevity

Live Forever Club - 12-Feb-2023

A strong genetic correlation between healthy diverse gut microbiome and healthy ageing was found

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Effects of intermittent fasting: An exploration

Live Forever Club - 31-Jan-2023

12 months of IF results in a range of biomarker improvements, but no significant reduction in inflammatory markers

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Open genes-comprehensive database of genes associated with aging and longevity

Lifespan.io (LEAF) - 24-Jan-2023

Open gene database simplifies the search for potential aging therapy targets

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Lifespan.io summarises the proceedings of the Buck Institute's Longevity Summit

Lifespan.io (LEAF) - 20-Jan-2023

Another reminder of the amount of research, with multiple approaches, about to go into clinical trials

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Dissociation of longevity targeted cell reprogram and somatic identity loss: An exploration

Live Forever Club - 17-Jan-2023

Most genes regulating cellular rejuvenation were not related to the increased occurrence of cancer

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Longevity Technology speaks to BioAge's CEO about clinical trial progress

Longevity Technology - 06-Jan-2023

Had success in reducing muscle atrophy and discovered novel class of molecules to target cognitive decline

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Genome length and the relationship with ageing: An analysis

Live Forever Club - 06-Jan-2023

Identifies a new target for ageing therapeutics - maintaining the abundance of long RNA transcripts

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Nuclear homeostasis contributes to promote longevity and fertility, IMBB scientists

Institute of Molecular Biology and Biotechnology (IMBB-FORTH) - 27-Dec-2022

Cells fundamental quality control mechanism to safeguard the nucleus-promote longevity and fertility

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SIRT6: Ageing, Metabolism, and Cardiovascular Diseases - A Review

Live Forever Club - 20-Dec-2022

SIRT6 has a vital role in cell metabolism which could lead to therapeutics for controlling senescence

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Cellular Senescence Network (SenNet) to identify and characterize senescent cells

Nature Aging - 20-Dec-2022

Grand plan includes creation of imaging datasets, new tools, techniques, and biomarker panels

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