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James Kirkland

Researcher on different aging related diseases.

The major research focus of James L. Kirkland, M.D., Ph.D., is the impact of cellular aging (senescence) on age-related dysfunction and chronic diseases, especially developing methods for removing these cells and alleviating their effects. Senescent cells accumulate with aging and in such diseases as dementias, atherosclerosis, cancers, diabetes and arthritis.

The goal of Dr. Kirkland's current work is to develop methods to remove these cells to delay, prevent, alleviate or partially reverse age-related chronic diseases as a group and extend health span, the period of life free of disability, pain, dependence and chronic disease.

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See also: Company Mayo Clinic

James Kirkland Blog Posts

Highlights of Ending Age-Related Diseases 2020
10-Sep-2020 Key points from 20 presentations from world-leading researchers

James Kirkland News

Comprehensive history and explanation of senescent cells

The Scientist - 01-Mar-2020

Including the latest on clinical trials of first-generation senolytics


Senolytics and their impact on anti-ageing

Technology Networks - 19-Sep-2019

Once more confirmed, senolytics reduce senescent cells by that preventing their effect of ageing


Small Mayo Clinic trial successfully removes senescent cells from humans

Mayo Clinic - 18-Sep-2019

Occasional senolytic use may be enough to keep senescent cells at bay


Senescent cells: short safety trial on humans successful

Science Daily - 07-Jan-2019

Next step is to go to an actual large-scale human trial


Senolytics for IPF human clinical trial results released

Life Extension Advocacy Foundation (LEAF) - 07-Jan-2019

Physical improvements recorded, but pulmonary function was unchcanged


Fisetin destroys senescent cells, but safe dosage not determined yet

Life Extension Advocacy Foundation (LEAF) - 26-Dec-2018

Includes table of fisetin content in range of fruits and vegetables