Highlights of Ending Age-Related Diseases 2020
Key points from 20 presentations from world-leading researchers
James Kirkland
Researcher on different aging related diseases
Dr. James L. Kirkland is a renowned medical researcher focused on cellular aging and its impact on age-related dysfunction and chronic diseases. His primary goal is to develop methods to remove senescent cells, which accumulate with aging and in diseases such as dementias, atherosclerosis, cancers, diabetes, and arthritis, to extend health span and improve quality of life.
Dr. Kirkland's research spans cellular senescence, senolytic drugs, and the relationship between diabetes, chronic diseases, and cellular senescence. He pioneered the concept of removing senescent cells to enhance health span and devised the first senolytic drugs, which selectively eliminate senescent cells.
His work has significant implications for patient care, as it aims to enhance health span and delay the onset of chronic age-related diseases collectively, rather than individually. This has the potential to reduce morbidity, mortality, and healthcare costs worldwide.
He's founder of Academy for Health & Lifespan Research.
Visit website: https://www.mayo.edu/research/faculty/kirkland-james-l-m-d-ph-d/bio-00096544
See also: 
Mayo Clinic
- Non-profit American academic medical center focused on health care, education, and research
Details last updated 01-Nov-2019
Mentioned in this Resource
Academy for Health and Lifespan Research (AHLR)
World's aging researchers unite to accelerate breakthroughs in longevity
James Kirkland is also referenced in the following:
Academy for Health and Lifespan Research (AHLR)
World's aging researchers unite to accelerate breakthroughs in longevity
ARDD 2021 - 8th Aging Research and Drug Discovery Meeting
31-Aug-2021 to 03-Sep-2021
Online event about latest progress in the molecular, cellular and organismal basis of aging organized by University of Copenhagen chaired by Morten Scheibye-Knudsen, Daniela Bakula and Alex Zhavoronkov, and with many speakers.
ARDD 2023 - 10th Aging Research & Drug Discovery Meeting
28-Aug-2023 to 01-Sep-2023
Event about latest progress in the molecular, cellular and organismal basis of aging organized by University of Copenhagen
BSRA Annual Scientific Meeting 2023
06-Sep-2023 to 08-Sep-2023
A compelling lineup of speakers from all areas of the biology of ageing
Extending Human Healthspan and Longevity
19-May-2021
Online webinar focused on longevity extension without health related issues organized by The New York Academy of Sciences with Nir Barzilai and Pinchas Cohen as keynote speakers.
Global Healthspan Summit 2023
29-Nov-2023 to 30-Nov-2023
Longevity summit organised by Hevolution Foundation (Riyadh,Saudi Arabia)
Healthy Longevity Medicine Society (HLMS)
Medical society with focus on promoting longevity as a specialty area of modern healthcare
Longevity Leaders World Congress 2021
04-May-2021 to 07-May-2021
The virtual event for leaders in longevity science, technology, business and finance organized by Longevity Leaders (LSX).
Longevity Leaders World Congress 2022
26-Feb-2022 to 27-Feb-2022
Event for leaders in longevity science, technology, business and finance organized by Longevity Leaders (LSX)
Targeting Metabesity 2022
10-Oct-2022 to 13-Oct-2022
The Kitalys Institute virtual conference about going beyond treating individual diseases to extending healthy lifespan
James Kirkland Blog Posts
10-Sep-2020
James Kirkland Creations
James Kirkland News
Lifespan.io reports back from Aging Research and Drug Discovery Meeting (ARDD 2023)
Lifespan.io (LEAF) - 26-Sep-2023Key points from Arkadi Mazin's summary of 5 days of talks by geroscientists and biotech leaders
Healthy Longevity Medicine Society launches to promote longevity medicine
Longevity Technology - 27-Sep-2022Looks like it will act as an interface between longevity researchers and clinicians
Oral senolytics boosts geroprotective protein in mice and humans
Mayo Clinic - 15-Mar-2022Dasatinib+Quercetin restores a-klotho protein, which could combat ageing and disease in older people
Whole-body senescent cell removal improved brain health in mice
Lifespan.io (LEAF) - 22-Jan-2021Senolytic drug and cancer drug with quercetin improved age-related cognition
Nature Biotechnology reviews the state of play of senolytics
Nature Biotechnology - 12-Nov-2020In August, Unity announced that its lead drug candidate had failed to beat a placebo in reducing ...
Comprehensive history and explanation of senescent cells
The Scientist - 01-Mar-2020Including the latest on clinical trials of first-generation senolytics
Senolytics and their impact on anti-ageing
Technology Networks - 19-Sep-2019Once more confirmed, senolytics reduce senescent cells by that preventing their effect of ageing
Small Mayo Clinic trial successfully removes senescent cells from humans
Mayo Clinic - 18-Sep-2019Occasional senolytic use may be enough to keep senescent cells at bay
Senolytics for IPF human clinical trial results released
Lifespan.io (LEAF) - 07-Jan-2019Physical improvements recorded, but pulmonary function was unchcanged
Senescent cells: short safety trial on humans successful
Science Daily - 07-Jan-2019Next step is to go to an actual large-scale human trial
Fisetin destroys senescent cells, but safe dosage not determined yet
Lifespan.io (LEAF) - 26-Dec-2018Includes table of fisetin content in range of fruits and vegetables
Oral senolytics have big impact on old mice
Mayo Clinic - 09-Jul-2018Senolytic cocktail caused improved physical condition of elderly mice
Why a drug for aging would challenge Washington
Politico - 13-Dec-2017What if just one medical treatment could stave off heart disease, cancer and Alzheimer’s? First ...
To stay young, kill zombie cells
Nature - 24-Oct-2017Proof-of-concept trials starting that pit senolytic drugs against a range of age-related ailments...
The first senolytic drugs to target senescent cells
Mayo Clinic - 05-Sep-2017New platform will help to identify additional drugs that target ageing processes more quickly
Secret to old age health could lie in purging worn-out cells
New Scientist - 16-Sep-2015Cells eventually stop dividing to replace damaged neighbours and to into senescence. Senescent c...
Senolytics, A New Class Of Drugs, Slows Aging Process
Medical Daily - 11-Mar-2015Senolytics, a new class of drugs, might dramatically slow the aging process and so change the fac...
