Researcher on different aging related diseases.
The major research focus of James L. Kirkland, M.D., Ph.D., is the impact of cellular aging (senescence) on age-related dysfunction and chronic diseases, especially developing methods for removing these cells and alleviating their effects. Senescent cells accumulate with aging and in such diseases as dementias, atherosclerosis, cancers, diabetes and arthritis.
The goal of Dr. Kirkland's current work is to develop methods to remove these cells to delay, prevent, alleviate or partially reverse age-related chronic diseases as a group and extend health span, the period of life free of disability, pain, dependence and chronic disease.
He's founder of Academy for Health & Lifespan Research.
See also: Mayo Clinic - Non-profit American academic medical center focused on health care, education, and research
Mentioned in this Resource
James Kirkland is also referenced in the following:
Online event about latest progress in the molecular, cellular and organismal basis of aging organized by University of Copenhagen chaired by Morten Scheibye-Knudsen, Daniela Bakula and Alex Zhavoronkov, and with many speakers.
Online webinar focused on longevity extension without health related issues organized by The New York Academy of Sciences with Nir Barzilai and Pinchas Cohen as keynote speakers.
The virtual event for leaders in longevity science, technology, business and finance organized by Longevity Leaders (LSX).
James Kirkland Blog Posts
Highlights of Ending Age-Related Diseases 2020
10-Sep-2020 Key points from 20 presentations from world-leading researchers
James Kirkland News
Whole-body senescent cell removal improved brain health in mice
Lifespan.io (LEAF) - 22-Jan-2021
Senolytic drug and cancer drug with quercetin improved age-related cognitionRead more...
Nature Biotechnology reviews the state of play of senolytics
Nature Biotechnology - 12-Nov-2020
In August, Unity announced that its lead drug candidate had failed to beat a placebo in reducing ...Read more...
Comprehensive history and explanation of senescent cells
The Scientist - 01-Mar-2020
Including the latest on clinical trials of first-generation senolyticsRead more...
Senolytics and their impact on anti-ageing
Technology Networks - 19-Sep-2019
Once more confirmed, senolytics reduce senescent cells by that preventing their effect of ageingRead more...
Small Mayo Clinic trial successfully removes senescent cells from humans
Mayo Clinic - 18-Sep-2019
Occasional senolytic use may be enough to keep senescent cells at bayRead more...
Senescent cells: short safety trial on humans successful
Science Daily - 07-Jan-2019
Next step is to go to an actual large-scale human trialRead more...
Senolytics for IPF human clinical trial results released
Lifespan.io (LEAF) - 07-Jan-2019
Physical improvements recorded, but pulmonary function was unchcangedRead more...
Fisetin destroys senescent cells, but safe dosage not determined yet
Lifespan.io (LEAF) - 26-Dec-2018
Includes table of fisetin content in range of fruits and vegetablesRead more...
Oral senolytics have big impact on old mice
Mayo Clinic - 09-Jul-2018
Senolytic cocktail caused improved physical condition of elderly miceRead more...
Why a drug for aging would challenge Washington
Politico - 13-Dec-2017
What if just one medical treatment could stave off heart disease, cancer and Alzheimer’s? First ...Read more...
To stay young, kill zombie cells
Nature - 24-Oct-2017
Proof-of-concept trials starting that pit senolytic drugs against a range of age-related ailments...Read more...
The first senolytic drugs to target senescent cells
Mayo Clinic - 05-Sep-2017
New platform will help to identify additional drugs that target ageing processes more quicklyRead more...
Secret to old age health could lie in purging worn-out cells
New Scientist - 16-Sep-2015
Cells eventually stop dividing to replace damaged neighbours and to into senescence. Senescent c...Read more...
Senolytics, A New Class Of Drugs, Slows Aging Process
Medical Daily - 11-Mar-2015
Senolytics, a new class of drugs, might dramatically slow the aging process and so change the fac...Read more...