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James Kirkland

Researcher on different aging related diseases.

The major research focus of James L. Kirkland, M.D., Ph.D., is the impact of cellular aging (senescence) on age-related dysfunction and chronic diseases, especially developing methods for removing these cells and alleviating their effects. Senescent cells accumulate with aging and in such diseases as dementias, atherosclerosis, cancers, diabetes and arthritis.

The goal of Dr. Kirkland's current work is to develop methods to remove these cells to delay, prevent, alleviate or partially reverse age-related chronic diseases as a group and extend health span, the period of life free of disability, pain, dependence and chronic disease.

He's founder of Academy for Health & Lifespan Research.

Visit website: https://www.mayo.edu/research/faculty/kirkland-james-l-m-d-ph-d/bio-00096544

See also: Health Organisation Mayo Clinic - Non-profit American academic medical center focused on health care, education, and research

Mentioned in this Resource

Institute

World's aging researchers unite to accelerate breakthroughs in longevity.

James Kirkland is also referenced in the following:

Institute

World's aging researchers unite to accelerate breakthroughs in longevity.

Event

Online event about latest progress in the molecular, cellular and organismal basis of aging organized by University of Copenhagen chaired by Morten Scheibye-Knudsen, Daniela Bakula and Alex Zhavoronkov, and with many speakers.

Event

Online webinar focused on longevity extension without health related issues organized by The New York Academy of Sciences with Nir Barzilai and Pinchas Cohen as keynote speakers.

Event
Longevity Leaders World Congress 2021
04-May-2021 to 07-May-2021

The virtual event for leaders in longevity science, technology, business and finance organized by Longevity Leaders (LSX).

Event
Longevity Leaders World Congress 2022
26-Feb-2022 to 27-Feb-2022

Event for leaders in longevity science, technology, business and finance organized by Longevity Leaders (LSX)

James Kirkland Blog Posts

Highlights of Ending Age-Related Diseases 2020
10-Sep-2020

Highlights of Ending Age-Related Diseases 2020

Key points from 20 presentations from world-leading researchers

James Kirkland News

Oral senolytics boosts geroprotective protein in mice and humans

Mayo Clinic - 15-Mar-2022

Dasatinib+Quercetin restores a-klotho protein, which could combat ageing and disease in older people

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Whole-body senescent cell removal improved brain health in mice

Lifespan.io (LEAF) - 22-Jan-2021

Senolytic drug and cancer drug with quercetin improved age-related cognition

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Nature Biotechnology reviews the state of play of senolytics

Nature Biotechnology - 12-Nov-2020

In August, Unity announced that its lead drug candidate had failed to beat a placebo in reducing ...

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Comprehensive history and explanation of senescent cells

The Scientist - 01-Mar-2020

Including the latest on clinical trials of first-generation senolytics

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Senolytics and their impact on anti-ageing

Technology Networks - 19-Sep-2019

Once more confirmed, senolytics reduce senescent cells by that preventing their effect of ageing

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Small Mayo Clinic trial successfully removes senescent cells from humans

Mayo Clinic - 18-Sep-2019

Occasional senolytic use may be enough to keep senescent cells at bay

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Senescent cells: short safety trial on humans successful

Science Daily - 07-Jan-2019

Next step is to go to an actual large-scale human trial

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Senolytics for IPF human clinical trial results released

Lifespan.io (LEAF) - 07-Jan-2019

Physical improvements recorded, but pulmonary function was unchcanged

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Fisetin destroys senescent cells, but safe dosage not determined yet

Lifespan.io (LEAF) - 26-Dec-2018

Includes table of fisetin content in range of fruits and vegetables

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Oral senolytics have big impact on old mice

Mayo Clinic - 09-Jul-2018

Senolytic cocktail caused improved physical condition of elderly mice

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Why a drug for aging would challenge Washington

Politico - 13-Dec-2017

What if just one medical treatment could stave off heart disease, cancer and Alzheimer’s? First ...

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To stay young, kill zombie cells

Nature - 24-Oct-2017

Proof-of-concept trials starting that pit senolytic drugs against a range of age-related ailments...

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The first senolytic drugs to target senescent cells

Mayo Clinic - 05-Sep-2017

New platform will help to identify additional drugs that target ageing processes more quickly

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Secret to old age health could lie in purging worn-out cells

New Scientist - 16-Sep-2015

Cells eventually stop dividing to replace damaged neighbours and to into senescence. Senescent c...

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Senolytics, A New Class Of Drugs, Slows Aging Process

Medical Daily - 11-Mar-2015

Senolytics, a new class of drugs, might dramatically slow the aging process and so change the fac...

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