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Josh Conway

Programmer and long-time supporter of rejuvenation biotechnology. Editor for LEAF.

Visit website: https://www.leafscience.org/author/josh/

See also: Institute Lifespan.io (LEAF) - Supporting the development of biotechnologies focused on ending age-related diseases

Articles written by Josh Conway

New research links DNA damage to incomplete gene transcription in aging

Lifespan.io (LEAF) - 15-Feb-2024

DNA damage accumulated with age worsens gene expression, affecting lifespan-determining pathways

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Metrnl, a protein that rises with exercise and shields against heart disease

Lifespan.io (LEAF) - 11-Jan-2024

It unlocks a potent anti-inflammatory defense mechanism within the body

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Metformin may minimize muscle loss in extended periods of bed rest

Lifespan.io (LEAF) - 24-Jul-2023

Improvements seen in muscle size and collagen deposits in older people with atrophy

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Novel method facilitates single-cell expansion of gene edited stem cells

Lifespan.io (LEAF) - 17-Jul-2023

Its polymer-supplemented culture system enables cell expansion without harmful mutations

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Revitalizing ageing stem cells: Unveiling the key to lasting youthfulness

Lifespan.io (LEAF) - 05-Jun-2023

Combination of factors that rejuvenate stem cells holds promise for aging and muscle-wasting diseases

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AI-driven breakthrough in senolytic drug discovery

Lifespan.io (LEAF) - 04-May-2023

Machine learning successfully identifies promising senolytic compounds to target ageing and age-related diseases

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Gut Microbiome: The Secret to Longevity in Centenarians

Lifespan.io (LEAF) - 06-Apr-2023

A youthful gut microbiome may contribute to enhanced longevity and overall health in people living past 100

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Correlation found between biological aging and cognitive decline using epigenetic clocks

Lifespan.io (LEAF) - 21-Nov-2022

The midlife study showed that the cognitive decliners age faster

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Therapeutic plasma exchange (TPE) rejuvenates multiple markers of gene expression

Lifespan.io (LEAF) - 25-Aug-2022

TPE causes systematic rejuvenation in human body by influencing multiple factors

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Senolytics may abate accelerated aging of cancer patients as seen in mice

Lifespan.io (LEAF) - 06-Jun-2022

Radiation-induced damage may lessen by removing senescent cells but senolytics may not reverse the damage

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The anti-malarial drug chloroquine increases lifespan in male mice

Lifespan.io (LEAF) - 30-May-2022

Chloroquine significantly interferes with the fundamental mechanisms behind autophagy

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New algorithm recognises senescent cells using physical morphology

Lifespan.io (LEAF) - 26-May-2022

in vivo analysis in mice confirms the imaging results against p21 biomarker

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Epigenetic age varies when people are exposed to significant stress

Lifespan.io (LEAF) - 23-May-2022

PhenoAge and GrimAge show epigenetic aging has downstream biological consequences

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Viral-vector gene therapies could unlock healthy life extension in humans

Lifespan.io (LEAF) - 12-May-2022

Lifespan of mice greatly extended even when treatment only started at the equivalent of 56 years old

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Alzheimers' treatment with stem cells is proven safer in Phase 1 clinical trial

Lifespan.io (LEAF) - 07-Apr-2022

Lomecel-B targets homing and microglia recruitment rather than differentiation

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Dasatinib plus quercetin combination may help preserve cognitive abilities in elderly people

Lifespan.io (LEAF) - 27-Jan-2022

Senolytics showed positive effects on rats but trials must confirm these findings on human brain

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Serum from older adults increased ageing markers and killed brain stem cells in humans

Lifespan.io (LEAF) - 16-Dec-2021

Brain volume and lifestyle can increase difference between chronological and biological age

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New study leading towards permanent youthful immune function

Lifespan.io (LEAF) - 18-Oct-2021

Significant alteration in lineage potential by NR treatment in mice

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Calorie restriction slows age-related stem cell exhaustion, improving overall health

Lifespan.io (LEAF) - 29-Sep-2021

Many studies underlined beneficial effects of calorie restriction in various tissues of mice

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Role of mature dendritic cells in thymic involution

Lifespan.io (LEAF) - 13-Sep-2021

Reversal of thymic aging possible through signaling based interventions

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