Josh Conway
Programmer and long-time supporter of rejuvenation biotechnology. Editor for LEAF.
Visit website: https://www.leafscience.org/author/josh/
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Lifespan.io (LEAF)
- Supporting the development of biotechnologies focused on ending age-related diseases
Details last updated 23-Oct-2019
Articles written by Josh Conway
New research links DNA damage to incomplete gene transcription in aging
Lifespan.io (LEAF) - 15-Feb-2024
DNA damage accumulated with age worsens gene expression, affecting lifespan-determining pathways
Read more...Metrnl, a protein that rises with exercise and shields against heart disease
Lifespan.io (LEAF) - 11-Jan-2024
It unlocks a potent anti-inflammatory defense mechanism within the body
Read more...Metformin may minimize muscle loss in extended periods of bed rest
Lifespan.io (LEAF) - 24-Jul-2023
Improvements seen in muscle size and collagen deposits in older people with atrophy
Read more...Novel method facilitates single-cell expansion of gene edited stem cells
Lifespan.io (LEAF) - 17-Jul-2023
Its polymer-supplemented culture system enables cell expansion without harmful mutations
Read more...Revitalizing ageing stem cells: Unveiling the key to lasting youthfulness
Lifespan.io (LEAF) - 05-Jun-2023
Combination of factors that rejuvenate stem cells holds promise for aging and muscle-wasting diseases
Read more...AI-driven breakthrough in senolytic drug discovery
Lifespan.io (LEAF) - 04-May-2023
Machine learning successfully identifies promising senolytic compounds to target ageing and age-related diseases
Read more...Gut Microbiome: The Secret to Longevity in Centenarians
Lifespan.io (LEAF) - 06-Apr-2023
A youthful gut microbiome may contribute to enhanced longevity and overall health in people living past 100
Read more...Correlation found between biological aging and cognitive decline using epigenetic clocks
Lifespan.io (LEAF) - 21-Nov-2022
The midlife study showed that the cognitive decliners age faster
Read more...Therapeutic plasma exchange (TPE) rejuvenates multiple markers of gene expression
Lifespan.io (LEAF) - 25-Aug-2022
TPE causes systematic rejuvenation in human body by influencing multiple factors
Read more...Senolytics may abate accelerated aging of cancer patients as seen in mice
Lifespan.io (LEAF) - 06-Jun-2022
Radiation-induced damage may lessen by removing senescent cells but senolytics may not reverse the damage
Read more...The anti-malarial drug chloroquine increases lifespan in male mice
Lifespan.io (LEAF) - 30-May-2022
Chloroquine significantly interferes with the fundamental mechanisms behind autophagy
Read more...New algorithm recognises senescent cells using physical morphology
Lifespan.io (LEAF) - 26-May-2022
in vivo analysis in mice confirms the imaging results against p21 biomarker
Read more...Epigenetic age varies when people are exposed to significant stress
Lifespan.io (LEAF) - 23-May-2022
PhenoAge and GrimAge show epigenetic aging has downstream biological consequences
Read more...Viral-vector gene therapies could unlock healthy life extension in humans
Lifespan.io (LEAF) - 12-May-2022
Lifespan of mice greatly extended even when treatment only started at the equivalent of 56 years old
Read more...Alzheimers' treatment with stem cells is proven safer in Phase 1 clinical trial
Lifespan.io (LEAF) - 07-Apr-2022
Lomecel-B targets homing and microglia recruitment rather than differentiation
Read more...Dasatinib plus quercetin combination may help preserve cognitive abilities in elderly people
Lifespan.io (LEAF) - 27-Jan-2022
Senolytics showed positive effects on rats but trials must confirm these findings on human brain
Read more...Serum from older adults increased ageing markers and killed brain stem cells in humans
Lifespan.io (LEAF) - 16-Dec-2021
Brain volume and lifestyle can increase difference between chronological and biological age
Read more...New study leading towards permanent youthful immune function
Lifespan.io (LEAF) - 18-Oct-2021
Significant alteration in lineage potential by NR treatment in mice
Read more...Calorie restriction slows age-related stem cell exhaustion, improving overall health
Lifespan.io (LEAF) - 29-Sep-2021
Many studies underlined beneficial effects of calorie restriction in various tissues of mice
Read more...Role of mature dendritic cells in thymic involution
Lifespan.io (LEAF) - 13-Sep-2021
Reversal of thymic aging possible through signaling based interventions
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