Musculoskeletal System News

AKL Therapeutics’ investigational senotherapeutics drug APPA beneficial for oral osteoarthritis

Longevity Technology - 20-Mar-2023

Senescent cells have become one of the most promising targets for healthy aging research

Restoring glutathione -potential therapy could prevent old impaired stem cells from ever developing

UCLA Health - 27-Feb-2023

Higher levels of glutathione better at muscle repair while low levels of the same are bad at it

Exploring mesenchymal stem cell derived exosomal therapy as intervertebral disc degeneration cure

Live Forever Club - 08-Feb-2023

MSCExos shown to improve osteoporosis by promoting osteoclast cell proliferation and formation of blood vessels

Phase 2 clinical trial of lead drug candidate MYMD-1- a therapy for delaying aging

Business Wire - 26-Jul-2022

Sarcopenia drug trial shows no evidence of toxicity or safety issues

Urolithin A can increase mitochondrial health in living joint tissue and improved mobility

Business Wire - 07-Jul-2022

Mitopure can improve mitochondrial health and counteract age-related muscle function decline

Sarconeos BIO101 in development for the treatment of Sarcopenia by Biophytis

Yahoo! finance - 27-Jun-2022

SARA-INT Phase 2 study and SARA Phase 3 study milestones in developing sarconeos

Scientists built a functional human tendon using 3D cryobioprinting

3D Printing Industry - 07-Feb-2022

A breakthrough technique to print complex tissues that can be stored for later use

A natural cholesterol metabolite with senolytic effect in mice and humans

Buck Institute - 02-Feb-2022

New class of senotherapeutic drugs that could possibly target various diseases and ageing

Senolytics promotes wound healing in the aged but not in young mice

Lifespan.io (LEAF) - 22-Dec-2021

Dasatinib plus quercetin slow down muscle regeneration in young mice

MyMD Pharmaceuticals begins phase 2 trial of TNF-inhibitor in January 2022

Longevity Technology - 14-Dec-2021

Potential oral treatment to prevent sarcopenia and frailty, and extend healthy lifespan

Valuable insight into the influence of age-associated humoral factors

Genetic Engineering & Biotechnology News (GEN) - 07-Dec-2021

An injection of extracellular vesicles improve muscle regeneration

A powerful platform to facilitate rehabilitation and musculoskeletal diseases

Medgadget - 24-Nov-2021

Thin, wireless, battery-free and multimodal musculoskeletal biointerfaces

Senolytic cocktail reduces age-related spinal disc degeneration in mice

Lifespan.io (LEAF) - 21-Sep-2021

Dasatinib and quercetin combo preserves spinal discs to target age-related back pain

A single protein reversed senescence in skeletal muscle cells

University at Buffalo - 17-Sep-2021

NANOG targets multiple ageing mechanisms - insights may help develop new therapies for age-related disorders

Role of Neuromuscular junction in ageing and neuro muscular diseases

Fight Aging! - 17-Aug-2021

Neuromuscular junction: A potential therapeutic target in neuromuscular injury

Safer and faster treatment of tendon injuries with stem-cell fat grafts

Genetic Engineering & Biotechnology News (GEN) - 17-Aug-2021

Tendons regain their original healthy condition within 2 months of therapy in sheep

Skeletal stem cells delay bone healing and foster inflammageing in older people

Medical Xpress - 12-Aug-2021

Treating with BMP2 and Csf1 antagonist in mice restored youthfulness to the aged skeletal system

Clearing out aged cells with senolytics can relieve jaw pain

University of Connecticut (UConn) - 07-Jul-2021

Senolytics for cartilage and bone regeneration in jaw joints, proven effective in mice

Zoledronate - accidental discovery of drug use for life extension

Lifespan.io (LEAF) - 30-Jun-2021

Too early to tell whether off-patent drug's effects in fruit flies will be seen in humans

Returning function to paralysed upper limbs is the primary goal of Orthocell trial

The Market Herald - 21-Jun-2021

Peripheral nerve repair could benefit 3 million patients every year

Natural compound may help treat intervertebral disc degeneration

Lifespan.io (LEAF) - 12-May-2021

DHE slowed senescence in intervertebral discs of mice; but its use in anti-aging is still questionable

Low magnitude vibration to prevent/delay age-related bone loss in rats

Lifespan.io (LEAF) - 05-May-2021

Vibration treatment eliminates senescence of bone cells - may not be applicable to other tissues

Klotho protein reversed muscle ageing in old, but not older mice

eLife Sciences - 20-Apr-2021

Potential future treatment strategy to prevent sarcopenia when supplemented at a young age

Supplementation with nicotinamide riboside slows age-related bone loss

Fight Aging! - 14-Apr-2021

Long-term use of this supplement boosts NAD+ levels, lowering the risk of osteoporosis in mice

A man-made molecule that helps repair and regenerate muscle tissue

EurekAlert! - 23-Mar-2021

Givinostat induces stem cells to produce muscle making cells - promising therapy for age-related muscle loss