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Musculoskeletal System News

AKL Therapeutics’ investigational senotherapeutics drug APPA beneficial for oral osteoarthritis

Longevity Technology - 20-Mar-2023

Senescent cells have become one of the most promising targets for healthy aging research

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Restoring glutathione -potential therapy could prevent old impaired stem cells from ever developing

UCLA Health - 27-Feb-2023

Higher levels of glutathione better at muscle repair while low levels of the same are bad at it

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Exploring mesenchymal stem cell derived exosomal therapy as intervertebral disc degeneration cure

Live Forever Club - 08-Feb-2023

MSCExos shown to improve osteoporosis by promoting osteoclast cell proliferation and formation of blood vessels

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Phase 2 clinical trial of lead drug candidate MYMD-1- a therapy for delaying aging

Business Wire - 26-Jul-2022

Sarcopenia drug trial shows no evidence of toxicity or safety issues

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Urolithin A can increase mitochondrial health in living joint tissue and improved mobility

Business Wire - 07-Jul-2022

Mitopure can improve mitochondrial health and counteract age-related muscle function decline

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Sarconeos BIO101 in development for the treatment of Sarcopenia by Biophytis

Yahoo! finance - 27-Jun-2022

SARA-INT Phase 2 study and SARA Phase 3 study milestones in developing sarconeos

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Scientists built a functional human tendon using 3D cryobioprinting

3D Printing Industry - 07-Feb-2022

A breakthrough technique to print complex tissues that can be stored for later use

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A natural cholesterol metabolite with senolytic effect in mice and humans

Buck Institute - 02-Feb-2022

New class of senotherapeutic drugs that could possibly target various diseases and ageing

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Senolytics promotes wound healing in the aged but not in young mice

Lifespan.io (LEAF) - 22-Dec-2021

Dasatinib plus quercetin slow down muscle regeneration in young mice

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MyMD Pharmaceuticals begins phase 2 trial of TNF-inhibitor in January 2022

Longevity Technology - 14-Dec-2021

Potential oral treatment to prevent sarcopenia and frailty, and extend healthy lifespan

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Valuable insight into the influence of age-associated humoral factors

Genetic Engineering & Biotechnology News (GEN) - 07-Dec-2021

An injection of extracellular vesicles improve muscle regeneration

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A powerful platform to facilitate rehabilitation and musculoskeletal diseases

Medgadget - 24-Nov-2021

Thin, wireless, battery-free and multimodal musculoskeletal biointerfaces

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Senolytic cocktail reduces age-related spinal disc degeneration in mice

Lifespan.io (LEAF) - 21-Sep-2021

Dasatinib and quercetin combo preserves spinal discs to target age-related back pain

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A single protein reversed senescence in skeletal muscle cells

University at Buffalo - 17-Sep-2021

NANOG targets multiple ageing mechanisms - insights may help develop new therapies for age-related disorders

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Role of Neuromuscular junction in ageing and neuro muscular diseases

Fight Aging! - 17-Aug-2021

Neuromuscular junction: A potential therapeutic target in neuromuscular injury

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Safer and faster treatment of tendon injuries with stem-cell fat grafts

Genetic Engineering & Biotechnology News (GEN) - 17-Aug-2021

Tendons regain their original healthy condition within 2 months of therapy in sheep

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Skeletal stem cells delay bone healing and foster inflammageing in older people

Medical Xpress - 12-Aug-2021

Treating with BMP2 and Csf1 antagonist in mice restored youthfulness to the aged skeletal system

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Clearing out aged cells with senolytics can relieve jaw pain

University of Connecticut (UConn) - 07-Jul-2021

Senolytics for cartilage and bone regeneration in jaw joints, proven effective in mice

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Zoledronate - accidental discovery of drug use for life extension

Lifespan.io (LEAF) - 30-Jun-2021

Too early to tell whether off-patent drug's effects in fruit flies will be seen in humans

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Returning function to paralysed upper limbs is the primary goal of Orthocell trial

The Market Herald - 21-Jun-2021

Peripheral nerve repair could benefit 3 million patients every year

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Natural compound may help treat intervertebral disc degeneration

Lifespan.io (LEAF) - 12-May-2021

DHE slowed senescence in intervertebral discs of mice; but its use in anti-aging is still questionable

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Low magnitude vibration to prevent/delay age-related bone loss in rats

Lifespan.io (LEAF) - 05-May-2021

Vibration treatment eliminates senescence of bone cells - may not be applicable to other tissues

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Klotho protein reversed muscle ageing in old, but not older mice

eLife Sciences - 20-Apr-2021

Potential future treatment strategy to prevent sarcopenia when supplemented at a young age

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Supplementation with nicotinamide riboside slows age-related bone loss

Fight Aging! - 14-Apr-2021

Long-term use of this supplement boosts NAD+ levels, lowering the risk of osteoporosis in mice

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A man-made molecule that helps repair and regenerate muscle tissue

EurekAlert! - 23-Mar-2021

Givinostat induces stem cells to produce muscle making cells - promising therapy for age-related muscle loss

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