Ageing damages mitochondria in muscle stem cells, leading to poor repair
Live Forever Club - 17-Aug-2025Therapies like exercise, drugs, and mitochondrial transfer offer hope
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Therapies like exercise, drugs, and mitochondrial transfer offer hope
Cartilage regeneration and reduced aging effects were observed in lab and animal studies
Study finds eggs maintain mitochondrial DNA integrity, unlike other body cells that age
The treatment may help people with diseases like Parkinson’s and heart problems
New investment fuels development of therapies targeting mtDNA-related energy disorders
Amino acids, like glutamine, keep mitochondria strong and slow ageing
Challenges like immune reactions, safety, and cost must be solved before
Scientists restore mitochondrial function using precise, CRISPR-free gene editing tools
This offers a new way to detect ageing-related changes in the body
Cholesterol impairs heart cell energy; new antibody therapy restores mitochondrial function
Their compound PZL-A shows promise and a related drug has entered trials
New research reveals how Parkin, PINK1, and OMA1 act as guardians of cellular energy centres
This breakthrough could lead to faster, more effective treatments for osteoarthritis
However, calcium handling worsens with age, affecting performance
Blocking stress response restored cell identity in mice, suggesting new treatment possibilities
Rats with fresh mitochondria survived more and recovered faster than those without
Mitochondrial NAD reservoirs may hold the key to ageing and therapy
Drugs like FGF21 analogs and metformin may extend lifespan
Early tests have shown VNA-318 could improve brain function and reduce brain cell damage
Long-term follow-up data and post-hoc analyses fuel optimism for treating mitochondrial diseases
Phase 2 trial on sonlicromanol to test its ability in improving patient's symptoms & quality of life
Chronic inflammation and fibrosis further damage the heart health
New research from Texas A&M develops nanoflowers to restore cellular energy
Boosting fat loss and preserving muscle with cutting-edge mitochondrial therapy
New funding propels innovative mitophagy-inducing lead compound into clinical trials targeting Alzheimer’s and Parkinson’s