$2.5M seed financing round closed by Cleara Biotech-targets cellular senescence
Longevity Technology - 03-Oct-2022Cleara’s novel FOXO4-based treatment approach-ability to eliminate biomarker-positive scarred cells
Peter de Keizer
Associate Professor at UMC Utrecht, Founder and Managing Director at Cleara Biotech
Peter de Keizer is the founder and managing director of Cleara Biotech B.V. He has 10+ years experience in valorization, intellectual property and preclinical research and development. He is and associate professor “Senescence in Cancer and Aging” at the University Medical Center Utrecht, the Netherlands. Peter was trained as a molecular biologist at Utrecht University and Harvard Medical School / Mass General Hospital, Boston, MA, USA (2004). He performed is PhD in 2009 in the field of FOXO signaling, knowledge he employed during his postdoctoral work at the Buck Institute for Research on Aging in Novato, CA, USA (2012) to develop the first compounds to eliminate senescent cells: FOXO4-based peptides. In 2017, he showed the translational power eliminating at least some types of senescent cells in mice, which resulted in a restoration of tissue homeostasis in models for aging and chemotoxicity (Cell, 2017; cited >700 times). In 2018, he joined the UMC Utrecht, the Netherlands, to investigate subtypes of senescence, where he became associate professor in 2020.
Visit website: https://www.clearabiotech.com/team/
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Details last updated 03-Jun-2019
Peter de Keizer News
Nature Biotechnology reviews the state of play of senolytics
Nature Biotechnology - 12-Nov-2020In August, Unity announced that its lead drug candidate had failed to beat a placebo in reducing ...
Labiotech gathers feedback from European biotechs on Unity failure
Labiotech - 28-Aug-2020General feeling that failures are bound to happen - but that their approaches can succeed
LEAF report from the Longevity Leaders Conference
Lifespan.io (LEAF) - 06-Feb-2019Encouraging signs from big companies - more interviews to follow
Cleara Biotech Joins the Race to Develop Senolytic Therapies
Lifespan.io (LEAF) - 09-Jul-2018This therapy uses a modified FOXO4 to promote apoptosis in senescent cells
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Peter de Keizer is also referenced in the following:
ARDD 2021 - 8th Aging Research and Drug Discovery Meeting
31-Aug-2021 to 03-Sep-2021
Online event about latest progress in the molecular, cellular and organismal basis of aging organized by University of Copenhagen chaired by Morten Scheibye-Knudsen, Daniela Bakula and Alex Zhavoronkov, and with many speakers.
Healthy Ageing (Virtual Conference)
25-May-2022 to 27-May-2022
Virtual conference by Wellcome Connecting Science with Judith Campisi as a keynote speaker
Articles written by Peter de Keizer
Anti-aging therapies targeting senescent cells: Facts and fiction
Cell - 29-Dec-2016Peter de Keizer of the Erasmus University Medical Center discusses strategy of removing senescent...
