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Anti-aging secrets of some animals, revealed

High cell damage tolerance, unfaltering telomeres, stem cells, to mention a few

08-Aug-2018

Key points from article :

Mole rats found alternative ways to cope with and tolerate high level of cell damage.

Oldest sea urchins rival oldest humans, quahog clams survive 500 years or more.

Steady lifelong supply of antioxidants in these species explains it.

Sea urchins leak out fewer ROS molecules, have sluggish metabolism.

Also, their telomeres don’t shorten, cells never cease dividing.

Bats can also preserve telomeres, Myotis genus live well more than 40 years.

Planaria with 1/3 pluripotent stem cells, ready to replenish damaged ones.

Hydra’s never-ending supply of stem cells traced to a gene called FOXO.

It also keeps their microbiomes,known to help fight aging, in check.

Immortal jellyfish known to age in reverse, due to transdifferentiation.

Rougheye rockfish, olm, Blanding's turtles, Eastern box turtles, also ageless marvels.

Mentioned in this article:

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Andrea Bodnar

Science Director, Gloucester Marine Genomics Institute

Calico

Combating aging and associated diseases. An Alphabet (Google) subsidiary.

Gloucester Marine Genomics Institute

World's First Marine Genomics Research Institute

James Coffman

Associate Professor, MDI Biological Laboratory

João Pedro de Magalhães

Professor of Molecular Biogerontology at University of Birmingham Institute of Inflammation and Ageing, consultant, futurist, speaker

MDI Biological Laboratory

Non-profit biomedical research institution improving human health

Rochelle Buffenstein

Staff Scientist/ Senior Principal Investigator, Calico

Thomas Bosch

Microbiologist, Professor, General BiologyKiel University

University of Liverpool

Public research university for UK and international students

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Mental Wellbeing