Key points and slides from the leading longevity conference hosted by Aubrey de Grey
Associate Professor at University of Rochester
Dr. Andrei Seluanov is a Professor of Biology at the University of Rochester. Dr. Seluanov’s research is focused on understanding the mechanisms of longevity and genome stability and on the studies of exceptionally long-lived and cancer-resistant mammals. He earned his BSc degree at Saint Petersburg State University, Russia and his Ph.D. at the Weizmann Institute of Science, Israel. Dr. Seluanov applies comparative biology approach to study aging and identified rules that control the evolution of tumor suppressor mechanisms depending on the species lifespan and body mass. More recently the focus of his research has been on the longest-lived rodent species in the naked mole rats and the blind mole rat. Seluanov’s group identified high molecular weight hyaluronan as the key mediator of cancer-resistance in the naked mole rat. Dr. Seluanov also demonstrated that DNA double-strand break repair becomes less efficient with aging and cellular senescence which leads to genomic instability and cancer, and this decline is rescued by Sirtuin 6. Seluanov’s work has been published in high profile journals including Nature and Science.
See also: University of Rochester - Private research university that grants undergraduate and graduate degrees, including doctoral and professional degrees
Andrei Seluanov is also referenced in the following:
Andrei Seluanov Blog Posts
Andrei Seluanov News
Naked mole rats' secret to long life could be unlocked for humans
University of Rochester - 23-Aug-2023
Scientists transfer the longevity gene to mice, extending their lifespan by 4.4%Read more...
SIRT6 gene improves DNA repair and increases lifespans
University of Rochester - 19-Apr-2019
Could it be tweaked to be even more efficient?Read more...
Novel approach using high molecular weight hyaluronan (HMW-HA) that has been determined to help the naked mole rat live cancer free
Kurzweil Network - 21-Jun-2013
Naked mole rats are subterranean rodents that have never been known to get cancer. Researchers h...Read more...