Senescent cell clearance could be one of the big treatments to at least slow down one of the underlying causes of aging.
Senescent cells have stopped dividing and, even worse, secrete tens of biologically active proteins, including pro-inflammatory factors, proteases, pro-fibrotic factors and growth factors. This Senescence Associated Secretory Phenotype (SASP) can induce senescence in neighbouring cells and is associated with many age-related diseases.
Draft page - more coming soon.
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Biotechnology company devoted to research of restoring human health
University of Exeter spinout aiming to develop senotherapeutic interventions
Biotech company that specializes in the discovery and validation of microRNA biomarkers.
Fast generation of functional therapeutic antibodies.
Company that target cancer by developing senescence inducing and senolytic (senescent cell killing) compounds.
Company that develops and invests in drugs and technologies which prolong human lifespan.
Anti-aging company developing senoblockers.
Biopharmaceutical company focused on discovering and developing drugs against aging disorders and cancer.
Biotechnology company producing therapy that targets and destroys senescent cells.
Biotechnology company focused on development of treatments for age related diseases..
Longevity Technology interviews Aubrey de Grey about senolytics and other senotherapeutics
Longevity Technology - 05-Aug-2021
Most approaches have their limitations but good progress is being made on several frontsRead more...
Clearing out aged cells with senolytics can relieve jaw pain
University of Connecticut (UConn) - 07-Jul-2021
Senolytics for cartilage and bone regeneration in jaw joints, proven effective in miceRead more...
Pro-repair microenvironment after injury is favored by targeting senescent cells
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Unity's senolytic drug reports positive phase 1 data in eye disease patients
FierceBiotech - 06-Jul-2021
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A 12-week strength-endurance training lowered senescence proteins in older people
Lifespan.io (LEAF) - 14-Jun-2021
New study using biomarkers proved the importance of regular exercise againRead more...