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Human trial proves niacin to be an effective NAD+ booster

Also a cheaper treatment for mitochondrial myopathy than NR and NMN supplements

08-Jun-2020

Key points from article :

Researchers have concluded a human trial using niacin for boosting NAD+.

Trial participants were given a steadily increasing dose of niacin.

From 250 mg/day to 750-1000 mg/day over a 4-month period, then 10-month follow-up treatment period.

Participants were organized into a study group of individuals with mitochondrial myopathy.

Treatment increased muscle NAD+ levels by 2.3-fold in 10 months.

The level of whole blood NAD+ increased to 8.2-fold at the 10-month mark.

Shows that supplements reach bloodstream in significant amounts to elevate NAD+ levels there.

It also improved body composition with improved muscle strength after 10 months.

Hepatic fat was halved and visceral fat was reduced by a quarter.

It increased fasting glucose levels though, in both groups after 4 months.

Researchers from University of Helsinki and Institute for Molecular Medicine Finland.

Also from Helsinki University Hospital and University of Iowa, published in Cell Metabolism.

Mentioned in this article:

Click on resource name for more details.

Cell Metabolism

Scientific Journal providing information from many different areas of metabolism

Helsinki University Hospital (HUS)

Group of hospitals in Helsinki

Institute for Molecular Medicine Finland (FIMM)

Research institute in Helsinki, Finland

The University of Iowa

Public Research university.

University of Helsinki

Multidisciplinary research university.

Topics mentioned on this page:
NAD+, Supplements