Key points from article :
Researchers have concluded a human trial using niacin for boosting NAD+.
Trial participants were given a steadily increasing dose of niacin.
From 250 mg/day to 750-1000 mg/day over a 4-month period, then 10-month follow-up treatment period.
Participants were organized into a study group of individuals with mitochondrial myopathy.
Treatment increased muscle NAD+ levels by 2.3-fold in 10 months.
The level of whole blood NAD+ increased to 8.2-fold at the 10-month mark.
Shows that supplements reach bloodstream in significant amounts to elevate NAD+ levels there.
It also improved body composition with improved muscle strength after 10 months.
Hepatic fat was halved and visceral fat was reduced by a quarter.
It increased fasting glucose levels though, in both groups after 4 months.
Researchers from University of Helsinki and Institute for Molecular Medicine Finland.
Also from Helsinki University Hospital and University of Iowa, published in Cell Metabolism.
