First-in-human, FDA-approved clinical trial to test a hydrogel on cardiac tissue
Medical Xpress - 12-Sep-2019Positive results seen in patients who had a heart attack more than a year before
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Biomaterial designed for repair of damaged cardiac muscle.
The VentriGel cardiac repair scaffold is a biomaterial designed specifically for repair of damaged myocardium.
Our goal for developing tissue engineering scaffolds is to mimic the in vivo extracellular matrix (ECM) for a particular tissue, providing a scaffold environment for cell-matrix interactions. VentriGel is the first product of its kind that contains myocardial specific extracellular matrix components. It is an injectable hydrogel derived from the native myocardial extracellular matrix, and thus mimics its native properties.
When native ECM is destroyed and replaced by a dense collagen scar, an abnormal microenvironment in the heart is created that prevents normal function. Once injected, the VentriGel cardiac repair scaffold offers a new healthy microenvironment.
Visit website: https://ventrixheart.com/product
See also: Ventrix - Company that produces biomaterial for cardiac repair for patients who had heart attack.
Details last updated 07-Nov-2019
Positive results seen in patients who had a heart attack more than a year before