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Laura Niedernhofer

Professor of Biochemistry, Molecular Biology and Biophysics at the University of Minnesota.

My research career has been dedicated to investigating the impact of DNA damage on the structure of DNA, cell function and organism health. The DNA in each of our cells is damaged thousands of times per day by exposure to environmental factors, dietary components, chemotherapeutic agents and even endogenous by-products of normal metabolism. Studying patients with rare diseases caused by inherited defects in DNA repair provides important insight into the consequences of DNA damage. These patients have a dramatically increased risk of cancer and age prematurely. We engineered mouse models of these genome instability syndromes as a sensitive tool to test hypotheses about how DNA damage promotes cancer and aging.

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See also: Academia University of Minnesota - Public Research university.

Laura Niedernhofer is also referenced in the following:


Online event about latest progress in the molecular, cellular and organismal basis of aging organized by University of Copenhagen chaired by Morten Scheibye-Knudsen, Daniela Bakula and Alex Zhavoronkov, and with many speakers.


Online webinar focused on longevity extension without health related issues organized by The New York Academy of Sciences with Nir Barzilai and Pinchas Cohen as keynote speakers.

Undoing Aging 2022
26-May-2022 to 28-May-2022

Focused on the cellular and molecular repair of age-related damage (Berlin)

Laura Niedernhofer News

Why a drug for aging would challenge Washington

Politico - 13-Dec-2017

What if just one medical treatment could stave off heart disease, cancer and Alzheimer’s? First ...