Dr. Frank M. Sacks is Professor of Cardiovascular Disease Prevention, Department of Nutrition, Harvard School of Public Health. He is also Professor of Medicine at Harvard Medical School, and a senior attending physician at Brigham and Women's Hospital where he has a specialty clinic in hyperlipidemia in the cardiovascular division. He is involved in research and public policy in lipid disorders, hypertension, nutrition, and cardiovascular disease.

His research program is a combination of laboratory research on human lipoprotein metabolism, and clinical trials that focus on nutrition and cardiovascular disease. The laboratory research concerns the acute and long-term effects of dietary and drug treatments on the function of lipoproteins in humans; the function in humans of specific apolipoproteins in VLDL, LDL, and HDL including apoC-III and apoE; metabolic pathways for HDL subtypes involved in reverse cholesterol transport in humans; and epidemiology of the relation between lipoprotein particle types based on apolipoprotein composition and CVD.