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bioRxiv

The preprint server for biology

bioRxiv (pronounced "bio-archive") is a free online archive and distribution service for unpublished preprints in the life sciences. It is operated by Cold Spring Harbor Laboratory, a not-for-profit research and educational institution. By posting preprints on bioRxiv, authors are able to make their findings immediately available to the scientific community and receive feedback on draft manuscripts before they are submitted to journals.

Visit website: https://www.biorxiv.org/

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Details last updated 02-Nov-2019

bioRxiv Blog Posts

Age Reversal in Mammals – Has This Now Been Achieved?
21-May-2020

Age Reversal in Mammals – Has This Now Been Achieved?

Biological age and biomarkers improved to that of rats half their age

bioRxiv News

Can machine learning discover lifespan-extending drugs for mice?

Can machine learning discover lifespan-extending drugs for mice?

Live Forever Club - 09-Nov-2024

This highlights promising paths for potential anti-ageing therapies

Epigenetic clocks reveal hidden health risks linked to biological ageing

Epigenetic clocks reveal hidden health risks linked to biological ageing

Live Forever Club - 27-Sep-2024

This study may help personalise health strategies for individuals at higher risk

Axolotls, known for their regeneration skills, show early-life epigenetic ageing

Axolotls, known for their regeneration skills, show early-life epigenetic ageing

Live Forever Club - 26-Sep-2024

Their abilities help reset biological age, offering insights for human longevity research

Bats and their remarkable resistance to age-related hearing loss

Bats and their remarkable resistance to age-related hearing loss

Live Forever Club - 20-Aug-2024

This discovery offers potential clues for preserving hearing in humans

Partial reprogramming rejuvenates the ageing mouse brain, improving memory

Partial reprogramming rejuvenates the ageing mouse brain, improving memory

Live Forever Club - 09-Aug-2024

This breakthrough offers hope for combating age-related cognitive decline

PEDF protein, found in young blood, rejuvenates aging cells and tissues in mice

PEDF protein, found in young blood, rejuvenates aging cells and tissues in mice

Live Forever Club - 24-May-2024

More research is needed, but this discovery offers hope for anti-aging therapies

Researchers explore the potential of sound waves for anti-ageing

Researchers explore the potential of sound waves for anti-ageing

Lifespan.io (LEAF) - 09-Feb-2024

Originally used to fight cancer, sound waves surprisingly revive old cells

A new method called FAST studies cellular ageing in cultured cells

A new method called FAST studies cellular ageing in cultured cells

Live Forever Club - 18-Jan-2024

FAST is precise and works with different cell types and microscopes

Blue zones: new data casts doubt on longevity hotspots

Blue zones: new data casts doubt on longevity hotspots

Slate - 29-Nov-2023

A Brit's skeptical take on Blue Zones and the search for eternal life

System Age epigenetic clock captured different patterns of ageing

System Age epigenetic clock captured different patterns of ageing

Lifespan.io (LEAF) - 21-Jul-2023

Novel method for precise estimation of biological age and disease risks with a single blood sample

The bowhead whale's secret to living over 200 years: Remarkable DNA repair mechanisms

The bowhead whale's secret to living over 200 years: Remarkable DNA repair mechanisms

Live Forever Club - 30-May-2023

Exceptional longevity and resistance to cancer holds potential implications for human health and ageing

GPT-3 and similar AI models can generate speech, using brain implants at a record-breaking speed

GPT-3 and similar AI models can generate speech, using brain implants at a record-breaking speed

Singularity Hub - 31-Jan-2023

The ultimate goal is to restore rapid communications to people who can no longer speak

Reversal of cell senescence using low frequency ultrasound

Reversal of cell senescence using low frequency ultrasound

Live Forever Club - 27-Jan-2023

Novel therapy killed some senescent cells, rejuvenated others, without harming healthy cells

Dissociation of longevity targeted cell reprogram and somatic identity loss: An exploration

Dissociation of longevity targeted cell reprogram and somatic identity loss: An exploration

Live Forever Club - 17-Jan-2023

Most genes regulating cellular rejuvenation were not related to the increased occurrence of cancer

Epigenetic age varies when people are exposed to significant stress

Epigenetic age varies when people are exposed to significant stress

Lifespan.io (LEAF) - 23-May-2022

PhenoAge and GrimAge show epigenetic aging has downstream biological consequences

Synergy of stem cell rejuvenation and senolytics promote longevity in fruit flies

Synergy of stem cell rejuvenation and senolytics promote longevity in fruit flies

Live Forever Club - 14-May-2022

Combined approach surprisingly eliminated the negative effects of individual treatments

Feeding dogs once daily might improve health and cognitive function

Feeding dogs once daily might improve health and cognitive function

Newsweek - 16-Nov-2021

This is another indicator that time restricted eating (TRE) has benefits in mammals

Frailty in old mice disappears with small extracellular vesicles from young mice stem cells

Frailty in old mice disappears with small extracellular vesicles from young mice stem cells

Fight Aging! - 09-Aug-2021

Molecular level benefits observed (inflammation, senescence) as well as physical ones

Galapagos giant tortoises kill damaged cells to resist cancer and ageing

Galapagos giant tortoises kill damaged cells to resist cancer and ageing

New Scientist - 20-Jul-2021

Large, long living animals offer insights on natural ways of cancer resistance

Restoration of youthful gene expression can be achieved alternatively

Restoration of youthful gene expression can be achieved alternatively

Lifespan.io (LEAF) - 11-Jun-2021

Possible ways of using reprogramming techniques to develop therapies


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