Scientific Journal devoted to age related diseases.
Aging Cell is a bi-monthly peer-reviewed, open access journal that aims to publish the highest quality, innovative research addressing fundamental issues in the biology of aging. For publication in Aging Cell, the work must provide a major new contribution to the understanding of aging and be of general interest to the community. Aging Cell seeks to cover all areas of geroscience, highlighting research that uncovers mechanistic aspects of the aging process, as well as the links between aging and age-related disease. Observations of novel aging processes without substantial mechanistic insight will be considered, but should be of especially high impact for the field. Topics including, but not limited to, nutrient-responsive signaling pathways, neuronal and endocrine signaling pathways, tissue interactions, genetic and epigenetic regulation and integrity, proteostasis, circadian rhythms, ROS and mitochondria, cellular senescence, stem cells, progerias and interventions that affect aging are encouraged.
Visit website: https://onlinelibrary.wiley.com/journal/14749726
See also: Wiley Online Library - Subscription-based library that is a collection of online resources covering life, health and physical sciences
Aging Cell News
Urolithin A can increase mitochondrial health in living joint tissue and improved mobility
Business Wire - 07-Jul-2022
Mitopure can improve mitochondrial health and counteract age-related muscle function declineRead more...
CD38 inhibitor increases lifespan and fitness in male mice
Lifespan.io (LEAF) - 05-Apr-2022
New anti-ageing approach to ramp up NAD levels and life extensionRead more...
Senolytics promotes wound healing in the aged but not in young mice
Lifespan.io (LEAF) - 22-Dec-2021
Dasatinib plus quercetin slow down muscle regeneration in young miceRead more...
Hyperactivation of senescent cells can trigger cytokine storm
Lifespan.io (LEAF) - 13-Aug-2021
Stimulated senescent human umbilical vein cells showed high susceptibility to inflammatory diseasesRead more...
Extracellular matrix gene expression: a novel approach to find geroprotective drugs
Lifespan.io (LEAF) - 11-Aug-2021
ECM reprogramming to identify drugs which can slow-down or prevent age-related diseasesRead more...
Clearing out aged cells with senolytics can relieve jaw pain
University of Connecticut (UConn) - 07-Jul-2021
Senolytics for cartilage and bone regeneration in jaw joints, proven effective in miceRead more...
A 12-week strength-endurance training lowered senescence proteins in older people
Lifespan.io (LEAF) - 14-Jun-2021
New study using biomarkers proved the importance of regular exercise againRead more...
2021 NIA's lifespan extension study results on mice out now
Longevity Technology - 01-Apr-2021
Longer lifespan in old male mice treated with 17‐α‐estradiol, but four other compounds had no effectRead more...
Boosting NAD+ levels with NR reverted symptoms of premature ageing disease
Lifespan.io (LEAF) - 31-Mar-2021
Benefits in older mice, but NR treatment in young mice increased inflammation and DNA damageRead more...
Rapamycin might not be an alternative for calorie restriction
Lifespan.io (LEAF) - 27-Jan-2021
Failed to mimic dietary restriction pathways on extending lifespan in progeroid miceRead more...
Whole-body senescent cell removal improved brain health in mice
Lifespan.io (LEAF) - 22-Jan-2021
Senolytic drug and cancer drug with quercetin improved age-related cognitionRead more...
Ageless Rx to investigate role of Rapamycin in human longevity
Longevity Technology - 12-Nov-2020
Set to launch Participatory Evaluation of Aging with Rapamycin for Longevity (PEARL) trialRead more...
OTC drug Ibuprofen could reverse age associated inflammation
Longevity Technology - 06-Nov-2020
A study on mice supported ibuprofen for use in neurodegenerative diseasesRead more...
Middle-aged mice live 10% longer with 4 days of CASIN injections
Lifespan.io (LEAF) - 14-Aug-2020
It would be interesting to see how long they lived with regular treatment through old-ageRead more...
Low stress hormone levels promotes premature ageing
Longevity Technology - 11-Aug-2020
Balance is key to everything especially with human bodyRead more...
Regulatory role of GDF 15 related to ageing and metabolism in humans and mice
Longevity Technology - 06-Aug-2020
Discovery of this homeostatic function just may be the first step but it looks promisingRead more...
Longitudinal DNA methylation is influenced by genetic, environmental factors
Longevity Technology - 03-Aug-2020
Decade-long studies of identical twins were able to reveal connectionsRead more...
Low cortisol levels can trigger 'macrophaging'
Medical Xpress - 01-Jul-2020
Learning this age-induced disruption of macrophage functions powers pharmaceutical researchRead more...
Navitoclax improved, now a safer senolytic drug choice
Fight Aging! - 09-Apr-2020
They found efficient way to increase its senolytic specificity, reduce platelet toxicityRead more...
Ageing in mice - the systemic burden of senescent cells matters
Fight Aging! - 06-Feb-2020
Senescent cell burden is a marker of disease free years ahead of lifeRead more...
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