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Aging Cell

Scientific Journal devoted to age related diseases.

Aging Cell is a bi-monthly peer-reviewed, open access journal that aims to publish the highest quality, innovative research addressing fundamental issues in the biology of aging. For publication in Aging Cell, the work must provide a major new contribution to the understanding of aging and be of general interest to the community. Aging Cell seeks to cover all areas of geroscience, highlighting research that uncovers mechanistic aspects of the aging process, as well as the links between aging and age-related disease. Observations of novel aging processes without substantial mechanistic insight will be considered, but should be of especially high impact for the field. Topics including, but not limited to, nutrient-responsive signaling pathways, neuronal and endocrine signaling pathways, tissue interactions, genetic and epigenetic regulation and integrity, proteostasis, circadian rhythms, ROS and mitochondria, cellular senescence, stem cells, progerias and interventions that affect aging are encouraged.

Visit website: https://onlinelibrary.wiley.com/journal/14749726

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See also: Publisher Wiley Online Library - Subscription-based library that is a collection of online resources covering life, health and physical sciences

Aging Cell News

CD38 inhibitor increases lifespan and fitness in male mice

Lifespan.io (LEAF) - 05-Apr-2022

New anti-ageing approach to ramp up NAD levels and life extension

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Senolytics promotes wound healing in the aged but not in young mice

Lifespan.io (LEAF) - 22-Dec-2021

Dasatinib plus quercetin slow down muscle regeneration in young mice

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Hyperactivation of senescent cells can trigger cytokine storm

Lifespan.io (LEAF) - 13-Aug-2021

Stimulated senescent human umbilical vein cells showed high susceptibility to inflammatory diseases

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Extracellular matrix gene expression: a novel approach to find geroprotective drugs

Lifespan.io (LEAF) - 11-Aug-2021

ECM reprogramming to identify drugs which can slow-down or prevent age-related diseases

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Clearing out aged cells with senolytics can relieve jaw pain

University of Connecticut (UConn) - 07-Jul-2021

Senolytics for cartilage and bone regeneration in jaw joints, proven effective in mice

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A 12-week strength-endurance training lowered senescence proteins in older people

Lifespan.io (LEAF) - 14-Jun-2021

New study using biomarkers proved the importance of regular exercise again

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2021 NIA's lifespan extension study results on mice out now

Longevity Technology - 01-Apr-2021

Longer lifespan in old male mice treated with 17‐α‐estradiol, but four other compounds had no effect

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Boosting NAD+ levels with NR reverted symptoms of premature ageing disease

Lifespan.io (LEAF) - 31-Mar-2021

Benefits in older mice, but NR treatment in young mice increased inflammation and DNA damage

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Rapamycin might not be an alternative for calorie restriction

Lifespan.io (LEAF) - 27-Jan-2021

Failed to mimic dietary restriction pathways on extending lifespan in progeroid mice

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Whole-body senescent cell removal improved brain health in mice

Lifespan.io (LEAF) - 22-Jan-2021

Senolytic drug and cancer drug with quercetin improved age-related cognition

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Ageless Rx to investigate role of Rapamycin in human longevity

Longevity Technology - 12-Nov-2020

Set to launch Participatory Evaluation of Aging with Rapamycin for Longevity (PEARL) trial

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OTC drug Ibuprofen could reverse age associated inflammation

Longevity Technology - 06-Nov-2020

A study on mice supported ibuprofen for use in neurodegenerative diseases

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Middle-aged mice live 10% longer with 4 days of CASIN injections

Lifespan.io (LEAF) - 14-Aug-2020

It would be interesting to see how long they lived with regular treatment through old-age

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Low stress hormone levels promotes premature ageing

Longevity Technology - 11-Aug-2020

Balance is key to everything especially with human body

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Regulatory role of GDF 15 related to ageing and metabolism in humans and mice

Longevity Technology - 06-Aug-2020

Discovery of this homeostatic function just may be the first step but it looks promising

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Longitudinal DNA methylation is influenced by genetic, environmental factors

Longevity Technology - 03-Aug-2020

Decade-long studies of identical twins were able to reveal connections

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Low cortisol levels can trigger 'macrophaging'

Medical Xpress - 01-Jul-2020

Learning this age-induced disruption of macrophage functions powers pharmaceutical research

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Navitoclax improved, now a safer senolytic drug choice

Fight Aging! - 09-Apr-2020

They found efficient way to increase its senolytic specificity, reduce platelet toxicity

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Ageing in mice - the systemic burden of senescent cells matters

Fight Aging! - 06-Feb-2020

Senescent cell burden is a marker of disease free years ahead of life

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Treating with rapamycin improves blood flow to the brain in rats

Science Daily - 06-Nov-2019

Blood circulation in the brain didn't deteriorate even a bit for 15 months

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