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Aging Cell

Scientific Journal devoted to age related diseases.

Aging Cell is a bi-monthly peer-reviewed, open access journal that aims to publish the highest quality, innovative research addressing fundamental issues in the biology of aging. For publication in Aging Cell, the work must provide a major new contribution to the understanding of aging and be of general interest to the community. Aging Cell seeks to cover all areas of geroscience, highlighting research that uncovers mechanistic aspects of the aging process, as well as the links between aging and age-related disease. Observations of novel aging processes without substantial mechanistic insight will be considered, but should be of especially high impact for the field. Topics including, but not limited to, nutrient-responsive signaling pathways, neuronal and endocrine signaling pathways, tissue interactions, genetic and epigenetic regulation and integrity, proteostasis, circadian rhythms, ROS and mitochondria, cellular senescence, stem cells, progerias and interventions that affect aging are encouraged.

Visit website: https://onlinelibrary.wiley.com/journal/14749726

 AgingCell

See also: Publisher Wiley Online Library - Subscription-based library that is a collection of online resources covering life, health and physical sciences

Aging Cell News

Eating less, living longer: the positive effects of calorie restriction

International Institute on Ageing (INIA) - 16-Oct-2023

Modest calorie reduction can activate genes for healthy ageing

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Metformin may minimize muscle loss in extended periods of bed rest

Lifespan.io (LEAF) - 24-Jul-2023

Improvements seen in muscle size and collagen deposits in older people with atrophy

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Use of rilmenidine drug showed lifespan and healthspan benefits in both young and old animals

Longevity Technology - 25-Jan-2023

With a global ageing population, the benefits of delaying ageing, even if slightly, are immense

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Reprogramming by cellular rejuvenation in mice increases lifespan and health

Lifespan.io (LEAF) - 01-Nov-2022

Partial reprogramming extends healthspan and lifespan by single or lifelong treatment

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Metformin misinterpreted as antiaging drug via animal studies, TAME heads for future trials

SENS Research Foundation - 04-Oct-2022

More than 90% of drugs safe and effective when tested in experimental animals fail in human testing

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Urolithin A can increase mitochondrial health in living joint tissue and improved mobility

Business Wire - 07-Jul-2022

Mitopure can improve mitochondrial health and counteract age-related muscle function decline

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CD38 inhibitor increases lifespan and fitness in male mice

Lifespan.io (LEAF) - 05-Apr-2022

New anti-ageing approach to ramp up NAD levels and life extension

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Senolytics promotes wound healing in the aged but not in young mice

Lifespan.io (LEAF) - 22-Dec-2021

Dasatinib plus quercetin slow down muscle regeneration in young mice

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Hyperactivation of senescent cells can trigger cytokine storm

Lifespan.io (LEAF) - 13-Aug-2021

Stimulated senescent human umbilical vein cells showed high susceptibility to inflammatory diseases

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Extracellular matrix gene expression: a novel approach to find geroprotective drugs

Lifespan.io (LEAF) - 11-Aug-2021

ECM reprogramming to identify drugs which can slow-down or prevent age-related diseases

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Clearing out aged cells with senolytics can relieve jaw pain

University of Connecticut (UConn) - 07-Jul-2021

Senolytics for cartilage and bone regeneration in jaw joints, proven effective in mice

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A 12-week strength-endurance training lowered senescence proteins in older people

Lifespan.io (LEAF) - 14-Jun-2021

New study using biomarkers proved the importance of regular exercise again

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2021 NIA's lifespan extension study results on mice out now

Longevity Technology - 01-Apr-2021

Longer lifespan in old male mice treated with 17‐α‐estradiol, but four other compounds had no effect

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Boosting NAD+ levels with NR reverted symptoms of premature ageing disease

Lifespan.io (LEAF) - 31-Mar-2021

Benefits in older mice, but NR treatment in young mice increased inflammation and DNA damage

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Rapamycin might not be an alternative for calorie restriction

Lifespan.io (LEAF) - 27-Jan-2021

Failed to mimic dietary restriction pathways on extending lifespan in progeroid mice

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Whole-body senescent cell removal improved brain health in mice

Lifespan.io (LEAF) - 22-Jan-2021

Senolytic drug and cancer drug with quercetin improved age-related cognition

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Ageless Rx to investigate role of Rapamycin in human longevity

Longevity Technology - 12-Nov-2020

Set to launch Participatory Evaluation of Aging with Rapamycin for Longevity (PEARL) trial

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OTC drug Ibuprofen could reverse age associated inflammation

Longevity Technology - 06-Nov-2020

A study on mice supported ibuprofen for use in neurodegenerative diseases

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Middle-aged mice live 10% longer with 4 days of CASIN injections

Lifespan.io (LEAF) - 14-Aug-2020

It would be interesting to see how long they lived with regular treatment through old-age

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Low stress hormone levels promotes premature ageing

Longevity Technology - 11-Aug-2020

Balance is key to everything especially with human body

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