Key points from article :
Chronic consumption of a western diet leads to overeating and obesity due to elevations in peripheral endocannabinoid signaling.
Endocannabinoid system is located throughout the mammalian body, including the brain and all peripheral organs.
Participates in the control of many physiological functions in the body, including food intake, energy balance, and reward.
Targeting cannabinoid receptors with pharmacological inhibitors that do not reach the brain could be a safe therapeutic approach for the treatment of overeating and diet-induced obesity.
The study was published in the Physiology & Behavior journal.
