Senescence fuels heart disease: new ways to tackle ageing cells
Live Forever Club - 09-Nov-2024Targeting senescent cells may prevent disease progression and show promise
Aging
Bio-medical journal covering research on all aspects of gerontology
Aging publishes research papers in all fields of aging research including but not limited, aging from yeast to mammals, cellular senescence, age-related diseases such as cancer and Alzheimer’s diseases and their prevention and treatment, anti-aging strategies and drug development and especially the role of signal transduction pathways such as mTOR in aging and potential approaches to modulate these signaling pathways to extend lifespan.
The journal aims to promote treatment of age-related diseases by slowing down aging, validation of anti-aging drugs by treating age-related diseases, prevention of cancer by inhibiting aging. Cancer and COVID-19 are age-related diseases.
Visit website: https://www.aging-us.com/
Details last updated 30-Aug-2019
Aging News
Fibroblasts lose ability to support skin structure as we age
Live Forever Club - 10-Sep-2024Aged fibroblasts accumulate proteins internally instead of secreting them
Body's repair system falters with age as stem cells lose their regenerative power
Live Forever Club - 12-Apr-2024Machine learning reveals widespread decline in stem cell potency with age
Gut bacteria and blood molecules offer clues to why grip strength weakens with age
Live Forever Club - 21-Feb-2024Research opens doors for future interventions to prevent muscle loss
Metrnl, a protein that rises with exercise and shields against heart disease
Lifespan.io (LEAF) - 11-Jan-2024It unlocks a potent anti-inflammatory defense mechanism within the body
Activating SIRT6, a DNA repair protein, reduces damage in ageing cells
Live Forever Club - 01-Jan-2024SIRT6 activation may be a potential therapeutic target for osteoarthritis
Alcohol linked to changes in DNA that could lead to earlier ageing
Live Forever Club - 02-Nov-2023Effects of alcohol on DNA ageing are not limited to specific demographics
Insilico Medicine identifies potential targets for ageing and disease using AI
EurekAlert! - 27-Sep-2023Highlights the potential of AI to accelerate drug discovery for several diseases
Chemical cocktail able to reprogram cells to reverse ageing, without the need for gene therapy
Live Forever Club - 13-Jul-2023David Sinclair and team discovers potential new approach to treat age-related diseases and promote healthy aging
Correlation found between biological aging and cognitive decline using epigenetic clocks
Lifespan.io (LEAF) - 21-Nov-2022The midlife study showed that the cognitive decliners age faster
People with vulnerable mental state age faster than smokers
Interesting Engineering - 27-Sep-2022Psychological component should not be ignored in aging studies as they impact on biological age
The anti-malarial drug chloroquine increases lifespan in male mice
Lifespan.io (LEAF) - 30-May-2022Chloroquine significantly interferes with the fundamental mechanisms behind autophagy
New algorithm recognises senescent cells using physical morphology
Lifespan.io (LEAF) - 26-May-2022in vivo analysis in mice confirms the imaging results against p21 biomarker
Epigenetic age identifies risk of dementia later in life
Feinberg School of Medicine - 20-Apr-2022Epigenitic and brain aging markers provide insights on accelerated cognitive decline
Dasatinib plus quercetin combination may help preserve cognitive abilities in elderly people
Lifespan.io (LEAF) - 27-Jan-2022Senolytics showed positive effects on rats but trials must confirm these findings on human brain
In-silico drug modelling for treatment of stroke
Lifespan.io (LEAF) - 10-Aug-2021Rapamycin analogs may help prevent cerebral ischemia/reperfusion injury (CIRI)
DNA-damage or telomere shortening may not cause normal ageing
EurekAlert! - 08-Jun-2021Rapamycin fails to extend lifespan in telomerase-deficient mice, while improving lifespan by 39% in normal mice
SIRT6 overexpression delays ageing of heart cells in mice
Lifespan.io (LEAF) - 17-May-2021Anti-ageing therapies targeting sirtuins may slow down multiple effects of human ageing
Low magnitude vibration to prevent/delay age-related bone loss in rats
Lifespan.io (LEAF) - 05-May-2021Vibration treatment eliminates senescence of bone cells - may not be applicable to other tissues
Diet and lifestyle changes reversed epigenetic ageing in males
Lifespan.io (LEAF) - 19-Apr-2021Dietary, exercise, sleep, supplements, and breathing regimen for 8 weeks reduced epigenetic age by 2 years.
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