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New Drug Slows Down Heart Disease Progression

PCSK9 inhibitors are an effective therapy for lowering LDL cholesterol

14-Sep-2017

Key points from article :

PCSK9 inhibitors are an effective therapy for lowering LDL cholesterol.

Combination of evolocumab and statins significantly reduced risk of cardiovascular events.

Evolocumab is a human monoclonal antibody that inhibits proprotein convertase subtilisin-kexin 9.

PCSK9 protein reduces the liver’s ability to remove LDL cholesterol from the blood.

Patients with under 10 mg/dL LDL cholesterol had 40 % lower risk of CV events.

The study was published in The Lancet medical journal.

Mentioned in this article:

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Brigham and Women’s Hospital

Teaching hospital of Harvard Medical School

The Lancet

Medical journal covering general medicine

Topics mentioned on this page:
Heart Disease Drugs