Genes & Development publishes high-quality research papers of broad general interest and biological significance in the areas of molecular biology, molecular genetics, and related fields. In addition to Review Articles and Perspectives, Genes & Development publishes three research formats—Research papers, short Research Communications, and Resource/Methodology papers.

Genes & Development has been named one of the Top Five Research Journals in the field of Molecular Biology and Genetics. Genes & Development has an Impact Factor of 8.99 and is ranked #1 among Developmental Biology research journals, #4 in Genetics and Heredity, and #6 in Cell Biology (ISI Journal Citation Reports®, 2018).