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Experts made synthetic cells that multiply like natural bacteria

29-Mar-2021

Key points from article :

Synthetic cells made by combining components of Mycoplasma bacteria with a chemically synthesised genome.

Can grow and divide into cells of uniform shape and size, just like most natural bacterial cells.

In 2016, researchers at the J. Craig Venter Institute in San Diego created synthetic minimal cells (JCVI-syn3.0).

They weren’t splitting uniformly to produce identical daughter cells.

“Creators had thrown out all the parts of the genome that they thought were not essential,” - Elizabeth Strychalski, lead researcher.

Added seven genes to JCVI-syn3.0 to produce a new synthetic cell, to restore normal, uniform cell division and growth.

Two of the seven genes were known to be involved in cell division.

"Synthetic cells are a tool for both basic research and biotechnology," - Kate Adamala at the University of Minnesota.

“Potential applications are vast, in agriculture, nutrition, biomedicine and environmental remediation,” - Jef Boeke at NYU.

Research published in the journal Cell.

7 additional genes created normally dividing artificial cells - interesting tool for future research works

Mentioned in this article:

Academic

Research group leader of Cellular Engineering at National Institute

Institute

Non-profit genomics research institute.

Academic

Director of the Institute for Systems Genetics at NYU Langone Medical Center

Academic

Synthetic biologist and a professor of genetics at the University of Minnesota.