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CRISPR-Chip uses graphene transistors to detect genetic mutations

25-Mar-2019

Key points from article :

New hand-held device that can detect specific genetic mutations in a matter of minutes.

Engineers combined CRISPR with electronic transistors made from graphene.

CRISPR-Chip has been used to identify genetic mutations in Duchenne muscular dystrophy patients.

Uses a purified DNA sample without needing to amplify the DNA segment of interest with PCR.

Plan is to multiplex the device to simultaneously detect a number of genetic mutations in minutes.

Work by University of California, Berkeley and the Keck Graduate Institute (KGI) of The Claremont Colleges.

The study was published in Nature Biomedical Engineering.

Could reduce time and cost of DNA testing

Mentioned in this article:

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Academic

Professor of Bioengineering at Berkeley University of California.

Academia

Private graduate school in Claremont, California.

Academic

Assistant Professor of Biomedical Sciences at Keck Graduate Institute.

Journal

Scientific journal covering research of human disease, or its prevention, diagnosis and treatment.

Academic

Professor at UC Berkeley.

Academia

Public land-grant research university