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Antioxidant beta-carotene synthetic supplements -higher risk of cardiovascular disease and mortality


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Researchers took a look at data from 884 previous studies that involved 883,627 participants.

They analyzed the effects of various supplements—including omega fatty acids, magnesium, zinc, and others.

They found that synthetic supplements formulated with the antioxidant beta-carotene were connected to a higher risk of both cardiovascular disease (CVD) and all-cause mortality.

"The findings demonstrate the importance of optimal nutrition intake, particularly of specific nutrients such as omega-3 fatty acid and folate," Johna Burdeos, registered dietician.

"Nevertheless, the natural beta-carotene from foods, ... gets converted to vitamin A in the body," says Burdeos. "Vitamin A is essential for healthy eyes and skin."

The study was published in the Journal of the American College of Cardiology.

Taking too high of a supplement dose of any nutrient could potentially lead to adverse effects

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American College of Cardiology

Non-profit medical association advocating for quality cardiovascular care through education, research promotion and development

Johna Burdeos

Registered Dietitian