Science Translational Medicine is a weekly journal devoted to research and issues of strong interest to the translational medicine community. Translational medicine topics suitable for submission include any original research findings, discussions or analyses that move the field closer to the goal of improving human health, or the diagnosis and treatment of disease. Interdisciplinary approaches are particularly encouraged, for example, studies at the interface of engineering and diagnostics, chemistry and drug development, or cell biology and clinical medicine. We accept original research, as well as Reviews, Perspectives and Commentaries.