This episode explores the progress in combating ageing, featuring Aubrey de Grey, author of Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime. Aubrey, a pioneer in longevity science, co-founded the Methuselah Foundation, the SENS Research Foundation, and the Longevity Escape Velocity (LEV) Foundation, where he leads as President and Chief Science Officer.

Key Points:

This episode delves into the progress being made in ending ageing with Aubrey de Grey, a leading figure in longevity science. Aubrey discusses groundbreaking initiatives and the potential for transformative advancements in reversing human ageing.

• Foundation of Longevity Science: Aubrey outlines his pioneering "divide-and-conquer" strategy, focusing on repairing cellular and molecular damage, now widely recognized as the SENS approach to combating ageing.
• Robust Mass Rejuvenation (RMR): He describes the RMR project, a cutting-edge experiment combining multiple rejuvenation therapies in mice to delay ageing. This research aims to inspire breakthroughs applicable to human longevity.
• Role of Machine Learning: Aubrey highlights how AI technologies like AlphaFold and data analytics are accelerating progress in drug discovery and ageing-related research.
• Longevity XPRIZE: He introduces the $101 million XPRIZE Healthspan award, incentivizing the development of therapies that can significantly reverse biological ageing in humans by 2030.
• Public Perception Shift: Aubrey emphasizes the importance of changing societal attitudes toward ageing through high-impact scientific results and initiatives like the Dublin Longevity Declaration.
• Global Collaboration: The podcast underscores the importance of events like the Longevity Summit Dublin, where diverse experts and enthusiasts unite to share knowledge and advance the field.