Van Nedervelde is a futurist and transhumanist writer, activist, and speaker. He advocates for space settlements to avoid human extinction.

Van Nedervelde was an early developer in virtual reality. He is the founder of virtual reality & 3D graphics studio E-spaces, patent-filing inventor of C-Thru, applying VR to security systems, and co-CEO of X3D Technologies, Inc., a virtual worlds production company co-founded and co-owned by Hollywood movie-director Michael Bay. Van Nedervelde directed E-spaces’ production of twelve online 3D training simulators for British Petroleum and the broader oil & gas industry to certify Well Lease Operators in the maintenance & troubleshooting of oil & gas wells surface equipment. He also developed virtual reality projects for the Munich Airport Center, Simsala Grimm, virtual Europe, and the transhumanist themed sculpture in Martine Rothblatt’s Teresem Island

Van Nedervelde was the Executive Director for Europe of the nanotechnology think-tank, the Foresight Institute from 1997 to 2014. Van Nedervelde also holds the position of Global Task Force member for the Center for Responsible Nanotechnology. As Executive Director for Europe, Van Nedervelde interfaced with the media and represents the Institute at European Union events, including EU parliamentary hearings. He has spoken at various conferences including a working group on unconventional security threats, organized in Washington D.C. by the Strategic Assessments Group (SAG) of the US Central Intelligence Agency’s Directorate of Intelligence. Van Nedervelde co-authored the Foresight Guidelines on Molecular Nanotechnology and was cited in Ray Kurzweil’s book The Singularity Is Near.