More than 100 years ago, the major causes of death were infectious-related. However, over the past 100+ years, deaths related to infectious disease have been dramatically reduced. So can we say that the war against infectious disease is over?

Definitely not! Humans are completely outnumbered by microbes, including bacteria and viruses, by at least 1,000,000,000,000,000,000,000 to 1! Our existence is under constant microbial attack, and eventually, our immune system can't properly handle this challenge. Infectious microbes enter and live inside us, where they cause insulin resistance, inflammation, telomere shortening, and oxidative stress, four major theories about why we age. In addition, microbial burden is involved with the major causes of death in 2016, including cardiovascular disease, cancer, stroke, Alzheimer’s disease, and diabetes. We haven’t eliminated infectious disease, we have merely delayed it!

This book will present evidence that supports the hypothesis that microbial burden is a major cause of ageing and age-related disease. Also, how can we fight back? Microbes can enter us through the gut, skin, and mouth. Evidence about how to optimally fortify these barriers is presented.