Manlio Vinciguerra is a Principal Investigator at the International Clinical Research Center (ICRC), Brno, Czech Republic; and European Research Area (ERA) Chair in Translational Stem Cell Biology at the Medical University of Varna (MUV), Varna, Bulgaria. Previously he held a position of Senior Lecturer at the Institute for Liver and Digestive Health at the University College London (UCL), London, United Kingdom.

He received his PhD in Internal Medicine (2004) and research training at the University of Geneva, Switzerland, and at the European Molecular Biology Laboratory (EMBL), in Italy and in Germany (2005-2011). He obtained a degree in Biomolecular Sciences from the University of Catania, Italy, in 1999.

Vinciguerra unraveled important cellular signaling and epigenetics mechanisms involved in metabolic and infectious processes, stress and aging in the heart and in the liver, such as PI3K/AKT/mTOR pathway and sirtuins, using a systems biology approach in cells and rodent models. He is a member of Who's Who in Gerontology.