Dr. Kinoshita is performing many malignant brain tumor surgeries including awake surgeries for gliomas on a daily basis. He deeply believes that non-invasive imaging techniques are valuable information to enhance surgical precision and provide tailor made treatment for glioma patients. His research interest includes but not restricted to advanced MR imaging of the brain such as diffusion, perfusion and quantitative MR acquisition, PET imaging and molecular imaging using radiomics. He has also been participating in MR guided focused ultrasound surgery and demonstrated for the first time that macromolecules such as antibodies could be delivered beyond the blood-brain barrier in a site-specific fashion by MR guided microbubble enhanced focused ultrasound.