Dr Schott's research interests are centred on translational research in the dementias, including: the development and application of imaging and cerebrospinal fluid biomarkers in the degenerative dementias for early, specific diagnosis and disease tracking; atypical and young onset dementia; genotype/phenotype correlations in neurodegeneration; clinical trials; autoimmune dementia syndromes; and normal and abnormal ageing. He is involved in several national and international collaborations, including heading an international consortium to determine the genetics of posterior cortical atrophy. Dr Schott co-edited (with Prof Masud Husain) the Oxford Textbook of Cognition and Dementia, and authored the chapter on Alzheimer's disease and other dementias for the Oxford Textbook of Medicine.