Professor at the École Polytechnique Fédérale in Lausanne.
Johan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he directs the Laboratory for Integrated and Systems Physiology (LISP). Dr. Auwerx uses molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focuses on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors – a particular class of transcription factors – into drugs, which are now used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Founder of Academy for Health & Lifespan Research.
Visit website: https://www.epfl.ch/labs/auwerx-lab/
See also: Swiss Federal Institute of Technology Lausanne (EPFL) - University that specializes in natural sciences and engineering.
Mentioned in this Resource
Johan Auwerx is also referenced in the following:
Event about latest progress in the molecular, cellular and organismal basis of aging organized by University of Copenhagen
Johan Auwerx News
Restructured mitochondrial metabolism linked to survival of human eggs
STAT - 20-Jul-2022
Complex I production temporarily halted in quiescent oocytes, promoting fertilityRead more...
Boosting NAD+ reverses muscle ageing and associated diseases
Medical Xpress - 19-Jan-2021
Drugs boosting NAD+ target toxic proteins by turning on the mitochondrial functionRead more...