Jacob C. Kimmel earned a Ph.D. at the University of California San Francisco as part of the NSF Center for Cellular Construction, advised by Wallace Marshall and Andrew Brack. He leads a research program as a Computational Fellow at Calico combining computational and experimental biology to address aging. His recent work has focused on repurposing developmental programs to restore youthful gene expression in old cells. The group is looking at how aging manifests differently among diverse mammalian cell types, how stem cells age, and on developing methods for timelapse imaging and single cell RNA sequencing.