Our cancer research programme is providing a better understanding of the genetic abnormalities that underlie the development of cancer. By using high throughput methods to study the whole genome we are discovering how complex regulatory networks become the targets of cancer genes. Parallel studies of basic molecular mechanisms that control normal cells help us to define the specific pathways that become deregulated in cancer. 

Our research programmes in the discovery science arena are wide-ranging and cover cancer cell and stem cell biology, viral oncology (EBV and HPV) and genome biology. These combined approaches allow us to determine how genetic abnormalities lead to cancer and help us to identify molecular pathways that can be used as new targets for novel therapies. To support our research, we are developing new strengths in genomics and bioinformatics through our strong academic link with the Centre for Computational Biology and Bioinformatics.