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Biomarkers identified to help diagnose atrial fibrillation

Could enable point of care blood testing instead of current ECG screening

07-Jan-2019

Key points from article :

Atrial fibrillation (AF) is a heart rhythm disturbance, affecting 1.6m people in the UK.

At the moment, an electrocardiogram (ECG) is usually used to screen patients.

Blood samples were looked for 40 cardiovascular biomarkers, plus 7 clinical risk factors.

University of Birmingham found two biomarkers had a strong connection with AF.

Those most at risk of the condition were older, male and had a high BMI.

Biomarkers discovered were BNP and FGF-23.

Brain natriuretic peptide (BNP) is a hormone secreted by the heart.

Fibroblast growth factor-23 (FGF-23) is a protein responsible for phosphate regulation.

People could be screened by testing their blood for these two biomarkers.

People with atrial fibrillation are much more likely to develop blood clots and suffer from strokes.

The study was published in the European Heart Journal.

Mentioned in this article:

Click on resource name for more details.

European Heart Journal

Scientific Journal providing information about cardiovascular diesases

Institute of Cancer and Genomic Sciences

Institute for research into cancer and genomic medicine.

Institute of Cardiovascular Sciences

Leading institute in cardiovascular research.

University of Birmingham

Public research university located in Edgbaston, United Kingdom

Winnie Chua

Post-doctoral researcher at University of Birmingham.

Yanish Purmah

Specialist Registrar in Cardiology at Queen Elizabeth Hospital NHS Trust.

Topics mentioned on this page:
Diagnostics, Stroke