Scientists discover rapamycin's anti-ageing mechanism
Futurity - 24-May-2019Triggers lysosomes to degrade harmful substances that collect in ageing cells
Join the club for FREE to access the whole archive and other member benefits.
Professor of Biology at University of Michigan.
Experienced Professor with a demonstrated history of working in the higher education industry. Strong education professional with a Ph.D. focused in Neuroscience and Cell Biology.
We are interested in understanding the physiological and pathological functions of Transient Receptor Potential (TRP) ion channels, lysosome ion channels, and Ca2+ signaling.
The major interest in our lab is to understand how Ca2+ flux pathways, i.e, Ca2+-pemeant channels, at the cell surface and in intracellular organelles are precisely controlled (gated) by extracellular and intracellular signals, and how this information is transduced into physiological and pathological changes at the cellular and organismal levels. We use an integrative approach with state-of-art techniques including molecular biology, bioinformatics, biochemistry, immunochemistry, electrophysiology, fluorescence imaging, confocal microscopy, and mouse genetics. A current focus is TRP channels, a large superfamily of transmembrane proteins serving as molecular/cellular sensors for a variety of physiological/pathological functions.Visit website: https://lsa.umich.edu/mcdb/people/faculty/haoxingx.html
See also: University of Michigan - Public Research university
Details last updated 19-Dec-2019
Triggers lysosomes to degrade harmful substances that collect in ageing cells