Dotiwala studies the mechanisms by which cell-based innate and adaptive immunity destroy diverse non-viral pathogens, with the aim of applying these mechanistic insights to aid in designing better antimicrobial and anti-cancer therapies.

Dotiwala received an M.B.B.S. in Medicine from Grant Medical College, Mumbai, India, and a Ph.D. in Molecular and Cell Biology from Brandeis University. He was a postdoctoral research fellow at Harvard University and an Instructor in Pediatrics at Boston Children’s Hospital and Harvard Medical School, before joining Wistar as an assistant professor in 2017.